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BB Quiz1 Semi > Rh group (History to terminology) > Flashcards

Rh group (History to terminology) Flashcards

1
Q

ISBT number 004

A

Rh blood group

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2
Q

Convert the following genotypes from Wiener nomenclature to Fisher-Race and Rosenfield nomenclatures, and list the antigens present in each haplotype.

a. R1r
b. R2R0
c. RzR1
d. rr

A

R1r
DCe/dce
Rh:1, 2, -3, 4, 5

R2R0
DcE/Dce
Rh:1, -2, 3, 4, 5

RzR1
DCE/DCe
Rh:1,2,3, -4,5

ryr
dCE/dce
RH: -1,2,3,4,5

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3
Q

What theory in 1940s, said that each person inherits a set of Rh genes from each parent (one D or d, one C or c, one E or e), because Rh genes are thought to be CODOMINANT

A

Fisher-Race

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4
Q

Rh-hr terminology: presence of CE (with D)

A

Z

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5
Q

When was Rh phenotype was reported in order of DCE

A

1946

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6
Q

How are Rh antigens inherited?

A

Codominant alleles

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7
Q

Introduced a new terminologies for Rh group in 1962

A

Richard Rosenfield and Co workers

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8
Q

“C” gene frequency for RH antigens in Caucasians

A

70%

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9
Q

Rh was named from

A

Rhesus Monkey

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10
Q

antigen is most potent, found in 85% of the white population and is always significant for transfusion purposes

A

D antigen

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11
Q

This case is where Dr. Levine found that over 90% is rh neg mother and rh positive father.

A

Erythroblastosis fetalis

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12
Q

“e” gene frequency for RH antigens in Caucasians

A

98%

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13
Q

Interpret this using “Alphanumeric Terminology

1,2,-3,5

A

Presence of D, C, e but absence of c

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14
Q

Created to more accurately represent the serological daya and to be more compatible with computer use

A

Alphanumeric Terminology

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15
Q

This terminology may be considered the phenotypic expression of the haplotype

A

Rh-hr terminology

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16
Q

It represents the presence of a single haplotype expressing three different factors

A

agglutinogen

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17
Q

Termsed for Anti-rhesus produced by animals

A

Anti-LW

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18
Q

Most commonly use terminology for Rh grouping

A

Fisher-Race or DCE term

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19
Q

Reported an antibody made by guinea pigs and rabbits when transfused with Rhesus monkey

A

Dr. Landsteiner and Dr. Alexander S. Wiener

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20
Q

The complement of genes inherited from either parent

A

Haplotype

21
Q

Indicates that an individual’s rbc possess one particular Rh antigen (D antigen)

A

Rh positive

22
Q

Rh-hr terminology: indicates absence of antigen

A

r

23
Q

Under ISBT: what number was assigned to Rh blood group

A

004

24
Q

represents the absence of D antigen in fisher race theory

A

d (small d)

25
Q

Weiner symbol

A

Rh-hr

26
Q

who described an HTR on an obstetrical patient after delivering a stillborn infant in 1939

A

Dr. Philip Levine and Rufus Stetson

27
Q

There are reports about Hemolytic transfusion reactions & HDN in this year

A

1930s

28
Q

When was HDN first described?

A

1609

29
Q

presence of Ce without D

A

’

30
Q

Termed the fisher-race

A

Ronald Aylmer Fisher and Dr. Robert Russel Race

31
Q

No genetic basis, no involve theory of Rh inheritance

A

“Alphanumeric Terminology

32
Q

D gene frequency for RH antigens in Caucasians

A

85%

33
Q

This system has no genetic basis, nor was it proposed based on a theory of Rh inheritance, but it simply demonstrates the presence or absence of the antigen on the RBC.

A

Rosenfield (alphanumeric)

34
Q

Indicates presence of D for Rh-hr terminology

A

“R”

35
Q

Who termed the Rh-hr terminology

A

Dr. Alexander Weiner

36
Q

Number of digits per antigen under ISBT

A

6

37
Q

For ISBT: First 3 digits represents the ____ and the remaining 3 represent the ___

A
  1. system
  2. antigenic specificity
38
Q

C and c antigens for Fisher race recognizes what antigen

A

Anthetical

39
Q

establishes a uniform nomenclature that is both eye and machine readable and is in keeping with the genetic basis of blood groups

A

International Society of Blood Transfusion Committee

40
Q

What causes the erythroblastosis fetalis in the findinga of Dr. levine in 1941

A

Maternal antibody

41
Q

Who believed that there was one gene responsible for defining Rh that produced an agglutinogen

A

Weiner

42
Q

Rh antibodies reacts best at

A

37C

43
Q

Proposed a system that assigns a number to each antigen of the Rh system in order of its discovery or recognized relationship to the Rh system

A

Richard Rosenfield and Coworkers

44
Q

Second most important blood system in terms of transfusion

A

Rh group

45
Q

This terminology was followed for written communication

A

Fisher-Race

46
Q

Presence of cE without D

A

”

47
Q

Hemolytic disease of the fetus and newborn also called as

A

Erythroblastosis fetalis

48
Q

Rh-hr terminology: for presence of ce

A

0

49
Q

Presence of CE without D

A

y

BB Quiz1 Semi (5 decks)

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