rhabdomyolysis Flashcards
(9 cards)
1
Q
what is rhabdomyolysis ?
A
syndrome cause by muscle necrosis
2
Q
what are the causes of rhabdo ?
A
intense physical exersice
crush injuries
drugs
3
Q
what drugs are associated with rhabdo ?
A
statins and fibrates
4
Q
what are the muscle contents released in rhabdo ?
A
creatinine kinase
aldose
lactate dehydrogenase
potassium and phosphate
purines
5
Q
what causes the renal toxicity in rhabdo ?
A
myoglobin is toxic to the proximal tubule
6
Q
what is the feared complication associated with rhabdo ?
A
renal failure
7
Q
what are the symptoms of rhabdo ?
A
muscle pain
weakness
dark urine from the myoglobin
8
Q
what is the treatment for rhabdo ?
A
volume resuscitation
treat electrolyte abnormalities
dialysis
9
Q
what is the initial phase of rhabdo ?
A
hypocalcemia is common
