Rheum

Question 1

Pathognomonic sign of myotonic dystrophy

Answer 1

Percussion myotonia and grip myotonia

Question 2

Sx of Giant Cell/Temporal Arteritis

Answer 2

Headache
Vision loss
Low grade fever
Lethargy
LOA
LOW

Question 3

Types of seronegative spondyloarthropathy

Answer 3

1. Ankylosing spondylosis
2. Psioriatic arthritis
3. Reactive arthritis
4. IBD associated arthritis

Question 4

Definition of seronegative spondyloarthritis

Answer 4

Sponyloarthropathy negative for rheumatoid factor

Question 5

SLE vs Dermatomyositis malar rash

Answer 5

SLE spares nasolabial fold

Question 6

Vasculitis that is often associated with polyarthralgia rheumatica

Answer 6

Temporal Arteritis

Question 7

Mucocutaneous features of SLE via SLICC criteria

Answer 7

1. Malar rash
2. Discoid rash
3. Mucositis
4. Alopecia

Question 8

NEJM dx criteria for dermatomyositis and polymyositis

Answer 8

1) Symmetrical proximal myopathy/muscle weakness
2) Raised enzymes on biochemistry
3) EMG findings
4) Positive muscle biopsy
5) Cutaneous findings for DM

PM:4/5
DM 3/5 + cutaneous

Question 9

Ddx for proximal myopathy

Answer 9

Paraneoplastic:Dermatomyositis/Polymyositis
Endocrinopathies(Thyroid,Cushing,Acro)
Drug induced
Infective:polio
Congenital: DMD BMD Myotonic dystrophy

Question 10

Definition of oligoarthritis

Answer 10

2-4 joints involved

Question 11

SOAP MD BRAIN mnemonic for SLE diagnostic criteria

Answer 11

Serositis
Oral Ulcers
Arthritis
Photosensitivity

Malar rash
Discoid rash

Blood counts low
Renal nephritic
ANA
Immunologic tests
Neurological

Question 12

Serology for systemic sclerosis

Answer 12

1) anti-centromere (a/w limited SSc)
2) anti-Scl 70( a/w rapidly progressive diffuse SSc and limited SSc)

3) anti- RNA polymerase III (a/w diffuse SSc)

Question 13

Signs to look for in suspected Marfans syndrome

Answer 13

1. High arch palate
2. Arm span
3. Wrist sign
4. Thumb sign

Question 14

Serology for anti phospholipid syndrome

Answer 14

1) Lupus anticoagulant
2) anti cardiolipin
3) anti beta 2 glycoprotein

Question 15

Serology for SLE

Answer 15

1) anti dsDNA
2) anti nuclear antigen(ANA)
3) anti smith
4) anti Ro

Question 16

Serology for inflammatory myositis

Answer 16

anti- Mi2

Question 17

Serology for Sjogren’s syndrome

Answer 17

1) Anti Ro/SSA
2) Anti La/SSB

Question 18

Gene test for spondyloarthropathies

Answer 18

HLAB 27

Question 19

Triad of felty syndrome

Answer 19

1. Seropositive Rheumatoid arthritis with destructive arthropathy
2. Splenomegaly
3. Neutropenia

Question 20

DR POOH mnemonic for psoriatic nail changes

Answer 20

Dactylitis/ Discoloration
Ridging

Pitting
Oil Drop Sign
Onycholysis
Subungual Hyperkeratosis

Question 21

Most life threatening complication of reactive arthritis(Reiter’s)

Answer 21

Aortic regurgitation

Question 22

Triad of Reactive arthritis(Reiter’s)

Answer 22

Arthritis, conjunctivitis and urethritis

“Can’t pee, see or climb a tree”