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(MS 2) Musculoskeletal > Rheumatoid Arthritis: Medical Management > Flashcards

Rheumatoid Arthritis: Medical Management Flashcards

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1
Q

Rheumatoid Arthritis: Medical Management

Goal

A
  1. To decrease joint pain and swelling
  2. Achieve clinical remission
  3. Decrease the likelihood of joint deformity

4.Minimize disability

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2
Q

Rheumatoid Arthritis: Medical Management

Early RA

A
  1. Biologic and Non Biologic Disease Modifying Antirheumatic Drugs (DMARDs)
  2. Biologic Disease Modifying Antirheumatic Drugs (DMARDs)
  3. NSAID and specifically Cyclo-oxygenase 2 (COX-2) enzyme blockers
    - Celecoxib (Celebrex)
  4. Opioids and analgesics
  5. Corticosteroids or low dose prednisone
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3
Q

Rheumatoid Arthritis: Medical Management

Examples of Non Biologic Disease Modifying Antirheumatic Drugs (DMARDs)

A
  1. Methotrexate
  2. Leflunomide
  3. Sulfasalazine
  4. Hydroxychloroquine
  5. Minocycline
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4
Q

Rheumatoid Arthritis: Medical Management

Examples of Biologic Disease Modifying Antirheumatic Drugs (DMARDs)

A
  1. Abatacept
  2. Rituximab
  3. Tocilizumab
  4. Anakinra
  5. Adalimumab
  6. Infliximab
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5
Q

Rheumatoid Arthritis: Medical Management

Moderate, erosive RA

A
  1. Cyclosporine - an immunosuppressant maybe added to enhance the disease modifying effect of methotrexate
  2. A combination of one Nonbiologic DMARDs and one Biologic DMARDs
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6
Q

Rheumatoid Arthritis: Medical Management

Persistent, erosive RA

A
  1. Reconstructive surgery and Corticosteroids
  2. Synovectomy (excision of synovial membrane)
  3. Tenorrhaphy (suturing of tendon)
  4. Arthrodesis (surgical fusion of the joint)
  5. Corticosteroids
  6. Nonbiologic DMARDs
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7
Q

Rheumatoid Arthritis: Medical Management

Advanced, unremitting RA

A
  1. High dose Methotrexate, Cyclophosphamide, and Azathioprine (low dose antidepressant)
  2. Nutrition therapy
  3. Food selection should include 5 major groups
    - Grains
    - Vegetables
    - Fruits
    - Dairy
    - Protein
  4. Small frequent feedings
  5. Supplemental vitamins and minerals
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8
Q

New medication for RA

A
  1. Olumiant (Baricitinib)

S/E
1. URTI
2. Nausea
3. Herpes simplex and Herpes zoster

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9
Q

Rheumatoid Arthritis: Medical Management

Early RA

Used to prevent inflammation and joint damage

A

Biologic and Nonbiologic DMARDs

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10
Q

Rheumatoid Arthritis: Medical Management

Early RA

Specifically engineered to target the most prominent pro inflammatory mediators of RA

A

Biologic DMARDs

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11
Q

Rheumatoid Arthritis: Medical Management

Early RA

Used for pain and inflammation relief

A

NSAIDs and specifically Cyclo-oxygenase 2 (COX-2)

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12
Q

Rheumatoid Arthritis: Medical Management

Early RA

Periods of extreme pain

A

Opioids and Analgesics

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(MS 2) Musculoskeletal (91 decks)

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