RISK FACTORS, CAUSALITY, BRADFORD HILL CRITERIA Flashcards

1
Q

when was bradford hill criteria made

A

1965

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2
Q

what is bradford hill

A

Widely recognised as a basis for causality assessment in epidemiology
In order to say that an association is causal, it should meet as many from this criteria as possible:

1) Strength of the association
2) consistentecy
3)Specificity of the association
4) temporlaity
5) Biological gradient
6) plausible
7) coherance
8) experiment
9) analogy

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3
Q

most common risk measures

A

1) RR
2) attributable risk
3) ODDS

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4
Q

WHAT would make something a protective factor

A

if the RR <1

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5
Q

define Relative risk

help you remember you are dividing

A

A ratio of the incidence in the exposed group (IE) compared to the incidence in the unexposed group (INE) ∴ IE/INE

e.g smoking in causing cancer for example

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6
Q

attributable risk

help you remember you are taking away

A

the difference between the incidence in the exposed group and the incidence in unexposed group ∴IE – INE

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7
Q

odds ratio

A

the relationship pf the probability of occurrence of an event to that of non- occurrence.

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8
Q

what gives you A snapshot of disease distribution in a population at a given moment.

A

incidence

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9
Q

difference bbetwen incidence and prevelence

A

time interval in incidence you need to have a time interval

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10
Q

Methods for studying incidence
Sources:

A

Data from the patient and his/her family
Data from medical establishments
Data from death registries

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11
Q

morbity

A

any departure, subjective or objective from a state of physiological wellbeing. Usually accept as a statistical concept including all cases of diseases that the health system is informed about.

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12
Q

“Epidemic situation
Low level of health prevention and treatment”

what does this mean

A

high incidence and high prevelence

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13
Q

which group does an aged popuplaution fall under

A

low incidence + high prevelence

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14
Q

confounding variable

A

A confounding variable is a third variable that influences both the independent and dependent variables.

it has to affect both

e.g alchol and heart disease

but smking is a confounding variable as it affects both

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15
Q

definition of risk

A

Generally, risk refers to the probability that an event will
occur. In epidemiology, risk refers to the probability that
person, exposed to certain factors (risk factors) will
subsequently develop a particular disease.

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16
Q

whats odds ratio usually measured with

A

case control

17
Q

definition of proportion

A

Proportion is a ratio, measuring the number of specific events
out of total events. For example, the proportion of male patients
in a hospital is the number of males / all patients.

18
Q

definiton of ratio

A

Ratio is a quantitative measure of the relationship of two
(independent) rates or events which may not be a part of the
same denominator. For example, sex ratio is the number of men
/ number of women.

19
Q

definiton of ratio

A

Ratio is a quantitative measure of the relationship of two
(independent) rates or events which may not be a part of the
same denominator. For example, sex ratio is the number of men
/ number of women.

20
Q

definition of rate

A

measures the occurrence of an event in a population
over time. The persons in the denominator must reflect the
population from which the cases in the numerator arose. The
counts in the numerator and denominator should cover the same
time period. The persons in the denominator must be “at risk”
for the event, that is, it should have been possible for them to
experience the event.

21
Q

low incidence and low prevelence

A

Good level of health care
services with successful prevention and treatment of diseases

22
Q

ICD

A

is a system developed collaboratively between the World Health Organization and 10 international centres so that the medical terms reported by physicians, medical examiners, and coroners
on death certificates can be grouped together for statistical
purposes.
- The purpose of the ICD and of WHO sponsorship is to
promote international comparability in the collection,
classification, processing, and presentation of mortality
statistics.

23
Q

MOST CURRENT ICD

A

11 is officially in use
35 countries are using 11

24
Q

youtube video on odds

A

> 2 - considered meangingful
4- very strong