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Flashcards in RLS Deck (28)
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1

RLS OF Glycolysis converts glucose C6H12O6, into pyruvate

Phosphofructokinase - 1 (PFK-1) In Cytosol

2

RLS OF Gluconeogenesis

Fructose-1,6 bisphosphatase In Cytosol

3

RLS OF TCA cycle

Isocitrate Dehydrogenase

4

RLS OF Glycogen Synthesis

Glycogen Synthase

5

RLS OF Glycogenolysis

Glyogen Phosphorylase

*Deficient in McArle's Disease

6

RLS OF HMP Shunt

Glucose-6-phosphate dehydrogenase (G6PD)

7

RLS OF De Novo Pyrimidine Synthesis

Carbamoyl Phosphate Synthase II (CPS II)

*done in cytosol

8

RLS OF De Novo Purine Synthesis

Glutamine- PRPP Amidotransferase

9

RLS OF Urea Cycle

Carbamoyl Phosphate Synthase I (CPS I)

*done in mitochondria

10

RLS OF Fatty Acid Synthesis

Acetyl-CoA Carboxylase (ACC)

11

RLS OF Fatty Acid Oxidation

Carnitine Acetyltransferase I

12

RLS OF Ketogenesis

HMG-CoA Synthase

13

RLS OF Cholesterol Synthesis

HMG-CoA Reductase

14

Pyruvate converted to Oxaloacetate by?

Pyruvate carboxylase Need Biotin,ATP, and CO2;

Activated by acetyl-CoA

*mitochondria

15

Oxaloacetate converted to Phosphoenolpyruvate (PEP) by?

Phosphoenolpyruvate (PEP) Carboxykinase (in Cytosol);

Requires GTP

16

Ethanol to Acetaldehyde

Alcohol dehydrogenase *inhibited by Fomepizole;

Ethanol to Acetaldehyde = NAD to NADH In the Cytosol

17

Acetaldehyde to Acetate

Acetaldehyde Dehydrogenase
*inhibited by Disulfram/Antibuse;

(mitochondria) NADH increased

18

Fructose to Fructose 1P

Fructokinase Using ATP to ADP

*Deficiency is Essential Frucotosuria

19

Fructose 1p converted to Dihydroxyacetone and Glyceraldehyde by________ which converted to Glyceraldehyde 3-P

Aldolase B

*Deficiency is Fructose intolerance

20

Galactose goes to Galactitol

Aldose reductase

21

Galactose goes to Galactose 1P

Galactokinase Using ATP to ADP

*Deficiency is Galactokinase deficiency

22

Galactose 1-P goes to Glucose 1-p

Galactose 1 Phosphate Uridyl Transferase Using UDP-Glu to UDP-Gal (Severe galactosemia)

23

RLS of Heme Synthesis

Aminolevulinic Acid Synthase

24

RLS of Bile Acid Synthesis

7-Alpha hydroxylase

25

Glucose 6-phosphate to Glucose

Glucose 6 Phosphatase

26

Glucose to Glucose 6 Phosphate

Hexokinase / Glucokinase

27

Pyruvate goes to Acetyl-Coa

Pyruvate dehydrogenase

28

Phosphoenolypyruvate goes to Pyruvate in Glycolysis

Pyruvate Kinase