Rosh Material #2 Flashcards

(100 cards)

1
Q

substanc mc abused by schizophrenic pt’s

A

tobacco

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

primary feature of illness anxiety d.o

A

fear of a serious underlying medical condition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

drug that reduces frequency of inappropriate fantasies and sex drive (ex for pedophilic d.)

A

leuprolide acetate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

indications for hospitalization in depressed pt who expresses suicidal ideation (8)

A

recent suicide attempt
detailed suicide plan
inability to discuss safety planning
comorbid psychiatric d.o
agitation
impulsivity
severe hopelessness
poor social support

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

3 comorbid psychiatric conditions that indicate hospitalization for depressed suicidal pt

A

borderline pd
schizophrenia
bipolar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

rf for suicide

A

> 70 yo
male
poor health
hx mental illness
feeling hopeless/helpless
isolation
unemployment/stressful work situation
poor finances
previous suicide attempt
fam hx suicide/attempt
LBGTQ+

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what do you think when you see: acute brain syndrome

A

mc major symptom of PCP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is acute brain syndrome

A

disorientation combined w. confusion, lack of judgment, inappropriate affect, or memory loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

common PE finding of acute brain syndrome

A

nystagmus: horizontal, vertical, or rotary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

standard drug urine test can detect (7)

A

cocaine
amphetamines
benzos
barbs
natural opioids
cannabis
PCP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what are the synthetic opioids (can not be detected on urine drug screen)

A

fentanyl
methadone
+/- oxycodone (semisynthetic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

3 causes of false positives for opioids on urine drug test

A

poppy seeds
rifampin
fluoroquinolones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

which medications increase lithium levels (5)

A

ACEI
NSAIDs
thiazides
TCAs
metronidazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

weekly weight gain goal for inpatient anorexia pt

A

2-3 lb/week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

weekly wt gain goal for anorexia pt with partial hospital tx

A

1-2 lb/week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

weekly outpatient weight gain goal for anorexia pt

A

0.5-1 lb/week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

indications for hospitalization for anorexia pt (8)

A

HR < 40 bpm
bp < 80/60
orthostatic increase in pulse
decrease in SBP
cardiac dysrhythmia
BMI < 15
< 75% IBW
medical complications 2/2 malnutrition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

pharm for refractory anorexia that does not respond to 1st line tx

A

SGA - ex olanzapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what dietary deficiencies have been linked to ADHD

A

iron
zinc
omega 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

erections require increased vascular flow into the _ (2)
and reduced _

A

corpora cavernosa
corpus spongiousum

reduced venous outflow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what intrapenile substance increases during an erection

what substance is produced as a result

A

nitric oxide promotes generation of cyclic guianosine monophosphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

nitric oxide and cyclic guanosine monophosphate lead to _
which leads to erection

A

vasodilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

6 classes of medications associated w. decreased libido and sexual dysfxn

A

SSRIs
antiandrogens
5ARI’s
thiazides
spironolactone
opioids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what personality d.o is mc associated w. anorexia

A

ocd personality d.o

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
what lab test is most definitive in determining chronic AUD
carbohydrate deficient transferrin
26
first line tx for conduct d.o
multisystemic: family therapy, parent training, CBT, community consultation
27
besides multisystemic tx, what other non pharm tx are used for conduct d.o (4)
positive parenting program fast track therapeutic foster homes multidimensional foster care
28
malingering is associated w. _ incentinves factitious d.o is associated with _ incentives
malingering: external inventives factitious: non external incentives
29
what is required for dx of complicated grief rxn
extreme yearning for deceased at 12 mo after their death
30
what instrument is used to measure severity of GAD
hospital anxiety and dpn scale
31
t/f: most children w. conduct d.o will later develop antisocial pd
f!
32
what 3 antiepileptic drugs are associated w. sexual dysfxn
lamotrigine gabapentin topiramate
33
antipsychotic highly associated w. TD
quetiapine
34
mc manifestations of TD
oral facial lingual
35
2 drugs associated w. TD
antipsychotics metoclopramide
36
tx for mild TD
benzo
37
tx for localized and severe TD
botox
38
pathology of TD
hyperkinetic movements due to prolonged use of dopamine receptor blocking agents
39
t/f: TD is irreversible
f! *remission may occur months-years later*
40
first line tx for ADHD in peds: first line tx for ADHD in adults:
peds: behavior mods adults: stimulants
41
life threatening adverse effect of methadone
qt prolongation
42
3 features associated w. paranoid pd
feeling of exploitation/deception holding grudges interpret benign remarks as threatening
43
risk of lamotrigine if it is titrated up rapidly
SJS
44
moa for first gen antipsychotics
**D2 antagonists** *also antagonists of M1, H1, and alpha 1 receptors*
45
moa for second gen antipsychotics
**5HT2a an D2 antagonists rapid D2 dissociation 5H1a agonists** *also antagonists of M1, H1, and alpha 1 receptors*
46
mc type of hallucination in schizophrenia pt
auditory
47
3 red flags for factitious d.o
hx of multiple hospital admits willingness to undergo procedures deceptive behavior: ex forging/falsifying /exaggerating
48
spectrum of postpartum dpn
blues: 2-3 days postpartum dpn: first few months psychosis: days to 4-6 weeks
49
tx for postpartum blues
reassurance watchful waiting for dpn
50
pharm for postpartum dpn
sertraline paroxetine
51
tx for postpartum psychosis
antipsychotics inpatient
52
brief psychotic episode involves one or more psychotic symptoms that have a sudden onset and last at least _ and resolve within _
1 day 1 month
53
first line tx for brief psychotic episode
SGAs
54
gs assessment tool used for panic d.o
panic disorder severity scale
55
what classes of meds are associated w. neuroleptic malignant syndrome
**FGA:** haldol, fluphenazine - mc **SGA:** clozapine, risperidone, olanzapine **antiemetics:**metocopramide, promethazine withdrawal of **dopamine agonists**
56
quadrad of neuroleptic malignant syndrome
AMS hyperthermia lead pipe rigidity autonomic instability
57
lab finding of neuroleptic malignant syndrome
elevated CK
58
pharm for neuroleptic malignant syndrome
benzos
59
neuroleptic malignant syndrome rarely presents with _ which is one way it can be distinguished from serotonin syndrome
hyperreflexia
60
EKG finding of neuroleptic malignant syndrome
generalized slow wave activity
61
disorders of arousal from NREM sleep in peds
confusional arousals sleep walking sleep terrors
62
parasomnias associated w. REM sleep in peds
nightmares sleep paralysis REM sleep behavior d.o parasomnia overlap d.o
63
what insomnia drug is best for sleep maintenance what is its MOA
doxepin H1 receptor antagonist
64
what insomnia drug is best for sleep onset what is its MOA
ramelteon melatonin agonist
65
what insomnia drugs are used for sleep onset AND sleep maintenance what are their MOAs
lemborexant - orexin antagonist suvorexant - orexin antagonist trazadone - 5HT, alpha-1, H1 antagonist
66
what OTC supplement is used to induce vomiting what complication is associated w. it
syrup of ipecac ipecac induced myopathy/cardiomyopathy
67
long tangent of unrelated conversation before arriving at an answer
circumstantial speech
68
long tangent of unrelated conversation without arriving at an answer
tangential speech
69
disorganized speech with repetitive words
verbigeration
70
words strung together without making sense
word salad
71
rapidly shifting between topics that have no connection
loose association
72
gad typically begins in what age group
early adulthood
73
pharm for binge eating d.o (3)
lisdexamfetamine topiramate SSRIs
74
what phobia is mc associated w. binge eating d.o
specific phobia
75
major differentiation btw somatic sx d.o and illness anxiety d.o
somatic sx d.o: genuine sx w.o an identifiable cause illness anxiety d.o: obsession w. illness +/- somatic sx
76
what 2 antipsychotics are mc associated w. weight gain
SGAs: clozapine olanzapine
77
SGA's have fewer EPS s.e, but higher incidence of (4)
wt gain -> metabolic syndrome qt prolongation hyperprolactinemia drowsy
78
3 subgroups of sx associated w. schizotypal pd
cognitive-perceptual odd/disorganized interpersonal
79
cognitive perceptual sx associated w. schizotypal pd
odd beliefs unusual perceptual experiences ideas of reference paranoia
80
what odd beliefs are associated w. schizotypal pd
magical thinking mind reading thought transfer
81
how long shold women w. postpartum dpn continue medication after sx resolution
6-9 months
82
_ are associated w. poor prognosis in schizophrenia
negative sx < 20 yo at onset coexisting OCD unstable employment insidious onset slow rate of dz progression male SUD low socioeconomic status fam hx schizophrenia
83
factors associated w. better prognosis in schizophrenia
dx > 20 yo catatonic paranoid stable employment acute onset rapid progression female no SUD middle/high socioeconomic status early intervention
84
order of tx for serotonin syndrome
1. benzos 2. cryptoheptadine
85
what do you think when you see a pt who smoked something bad at a party and presents w.: paranoia, avoidance of eye contact, sedation, diahoresis, vomiting, bradycardia, hypotn, and extreme muscle pain UA is negative
synthetic cannabinoids
86
street names for synthetic cannabinoids
K2/K3 spice crazy clown krypton aztec fire happy tiger incense
87
first and 2nd line tx for bipolar 1 mania
1. lithium PLUS antipsychotic 2. valproate PLUS antipsychotic - if contraindication for lithium
88
black box warning for valproate
hepatotoxicity
89
rf for PTSD
young age at time of trauma adverse childhood events female widowed/separated/divorced lower socioeconomic status/education fam hx poor social support severe stress rxn to event
90
rf for schizophrenia
brith during late winter/spring living further from the equator living in an urban area/industrialized country immigration advanced paternal age perinatal obstetric complications childhood trauma CNS infxns cannabis use
91
female athlete triad
low energy availability low bone mineral density amenorrhea
92
pathophys behind dystonias related to first gen antipsychotics
dopamine receptor blockade
93
tx for acute dystonic rxn related to first gen antipsychotics
anticholinergics: diphenhydramine benztropine
94
what pharm is first line tx for adult pt w. ADHD who has a hx of substance use disorder
atomoxetine
95
piloerection, diaphoresis, yawning restlessness, dysphoria, myalgia, arthralgia, rhinorrhea, lacrimation, n/v, diarrhea, palpitations
acute opioid withdrawal
96
acute opioid withdrawal is associated w. _
abrupt cessation of short acting opioids *heroin*
97
tx for acute opioid withdrawal
opioid agonists: methadone buprenorphine
98
6 specifiers for delusional d.o
ertomanic grandiose jealous persecutory somatic bizarre content
99
tx for schizotypal pd
quetapine +/- stimulants
100
belief that irrelevant and innocuous things in teh world have great personal significance
ideas of reference