Salivary Glands

Question 1

Salivary glands are___ glands & ___ cells

Answer 1

exocrine
secretory

Question 2

what’s the order of development for the 3 major salivary glands?

Answer 2

Parotid anlagen are first to develop, then submandibular gland, & then sublingual gland

Question 3

Parenchymal tissue (secretory) of the glands arises from the ___ in adults & ___ in developing fetus

Answer 3

proliferation of oral epithelium & ectoderm in the developing fetus

Question 4

Stroma (capsule & septae) of the glands originates from

Answer 4

mesenchyme that may be mesodermal or neural crest in origin

Question 5

Functions of the salivary glands

Answer 5

Protection
Buffering
Digestion
Antimicrobial
Antiviral
Antifungal
Maintenance of tooth integrity
Taste
Caries prevention
Temperature regulation

Question 6

w/o saliva, you’re prone to

Answer 6

infections

Question 7

What are the minor salivary glands? are they mucous, serous, or mixed?

Answer 7

Lingual
Anterior - mixed - mostly mucous
Posterior - mucous

Labial - mixed - mostly mucous

Buccal - mixed - mostly mucous

Palatine (hard & soft palate) - Mucous

Glossopalatine - mucous

Question 8

What is the new salivary gland called? Where’s it located & is it a minor or major salivary gland?

Answer 8

Tubarial gland
Location is above the torus tubarius, the section of the nasopharynx just behind the pharynx
A minor salivary gland

Question 9

Describe serous cells

Answer 9

• produce a thin watery secretion
• Also secrete polysaccharides
• Stain purple
• Has a rounded euchromatic nucleus surrounded by rough ER in the basal third of the cell

Question 10

There’s an abundance of ___ in apical cytoplasm (NOT ribosomes or mitochondria)

Answer 10

zymogen granules

Question 11

Where are serous cells found in the body?

Answer 11

Found in acinar cells of pancreas, parotid, gastric chief cells, & intestinal paneth cells

Question 12

Describe mucous cells

Answer 12

• produce a more viscous secretion
• Production, storage, & secretion of proteinaceous material; smaller zygomatic component
• More carbohydrates (attached to mucins)
• More prominent golgi that adds carbohydrates to proteins
• Less prominent rough ER & mitochondria

Question 13

What are the major salivary glands?

Answer 13

Parotid, submandibular & sublingual

Question 14

All salivary glands are ___ glands

Answer 14

compound tubuloalveolar

Question 15

The salivary gland has intercalated, striated & ___ ducts & is composed of ___ acini & ___ cells

Answer 15

Secretory
Terminal
Myoepithelial

Question 16

Parotid anlagen are first to develop, & become encapsulated before or after the submandibular

Answer 16

AFTER

Question 17

What happens before encapsulation of the parotid gland?

Answer 17

the lymphatic system develops - there are intraglandular lymph nodes & lymphatic channels that become entrapped within the parotid gland

Question 18

Describe the parotid gland. Provides ___ of total salivary volume. What’s its main duct in?

Answer 18

• Largest encapsulated salivary gland
• Pure serous
• No serous demilunes (b/c only 1 cell type)
• Provides 25% of total salivary volume
• Main duct in Stenson’s duct

Question 19

What gland is this?

Answer 19

Parotid

Question 20

What gland is this?

Answer 20

Parotid

Question 21

Describe submandibular glans. It provides ___ of total salivary volume. What’s its main duct?

Answer 21

• 2nd largest encapsulated salivary gland
• Mixed - predominantly serous
• Provides 60-65% of total salivary volume
• Main duct is Wharton’s duct

Question 22

What salivary gland is this?

Answer 22

Submandibular

Question 23

What salivary gland is this?

Answer 23

Submandibular

Question 24

Describe the sublingual gland. It provides ___ of total salivary volume. What’s its main duct?

Answer 24

• Smallest salivary gland
• Unencapsulated gland
• Mixed - predominantly mucous
• Provides 10% of total salivary volume
• Main duct is Bartholin’s duct

Question 25

What salivary gland is this?

Answer 25

Sublingual

Question 26

What salivary gland is this? What else can you see in this image?

Answer 26

Sublingual Blood capillaries (RBC)

Question 27

Intercalated ducts are lined by ___. Where do they develop?

Answer 27

simple squamous to low cuboidal epithelial cells rich in carbonic anhydrase mucous glands

Question 28

Striated glands are ___ in mucous glands

Answer 28

nonexistent

Question 29

In striated glands, cells absorb ___ from the lumen & secrete ___ into the luen

Answer 29

Na+ & K+

Question 30

Striated ducts are ___ cells

Answer 30

simple cuboidal epithelial cells

Question 31

Excretory ducts are lined by

Answer 31

simple columnar epithelium proximally & stratified cuboidal (2 layers) or pseudostratified columnar epithelium distally

Question 32

Location & function of myoepithelial cells

Answer 32

- Found between the acinar cells & basal lamina - Function: contraction when gland is secreting & aid in the expulsion of saliva

Question 33

Effects of aging in relation to the salivary gland

Answer 33

- Acinar cells degenerate w/ age - Submandibular gland more sensitive to metabolic/physiologic change

Question 34

Salivary hypofunction examples

Answer 34

Candidiasis Lichen planus Burning mouth Aphthous ulcers Dental caries Xerostomia

Question 35

Less saliva production is connected to

Answer 35

dry eyes

Question 36

What is xerostomia?

Answer 36

Dry mouth - often due to medications or radiation

Question 37

Label

Answer 37

1. Basal lamina 2. Myoepithelial cells 3. Acinar cells 4. Acinus 5. Intercalated duct 6. Striated duct