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PHA 037 - PHARMACOLOGY > SAS 7 > Flashcards

SAS 7 Flashcards

1
Q

Bethanechol

A

motility

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2
Q

Neostigmine

A

motility

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3
Q

Metoclopramide and Domperidone

A

motility; D2 antagonist

AE: causes EPE

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4
Q

Macrolide: Erythromycin

A

motility

MOA: directly activates motilin receptor

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5
Q

Cholinergic drugs in GI are?

A

agonist of M3

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6
Q

Anti-cholinergic drugs in GI are?

A

antagonist of M3

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7
Q

Dicyclomine and hyoscyamine

A

IBS; Anticholinergic

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8
Q

Alosetron

A

IBS; 5-HT3 antagonist

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9
Q

Lubiprostone

A

IBS; chloride channel activators

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10
Q

Linaclotide

A

IBS; chloride channel activators

activates CFTR

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11
Q

Aminosalicylate

A

IBD, anticholinergic

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12
Q

Mesalamine compounds
Pentasa
Asacol
Liada

A

IBD, anticholinergic

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13
Q

Glucocorticoids
Prednisone, Prednisolone
Hydrocortisone
BUDENOSIDE

A

IBD, anticholinergic

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14
Q

Infliximab, adalimumab, golimumab, certolzumab

A

anti-TNF, IBD

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15
Q

Pancreatin (low concentration of lipase and proteolytic enzymes)

A

IBD

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16
Q

Pancrelipase

A

IBD

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17
Q

Ursodiol *inherent

A

Gallstones (bile)

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18
Q

5-HT3 antagonist:
ondaseTRON
graniseTRON
dolaseTRON
palonaseTRON

A

Anti-emetic

(M1, H1, NK1, 5-HT3)

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19
Q

Neurokinin antagonist:
AprepiTANT
FosaprepiTANT

A

Anti-emetic

(M1, H1. NK1, 5-HT3)

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20
Q

H1 antagonist:
Scopolamine

A

Anti-emetic

(M1, H1, NK1, 5-HT3)

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21
Q

LORAZEPAM AND DIAZEPAM

A

BZD, ANTI-EMETIC

22
Q

DRONABINOL

A

ANTI-EMETIC

23
Q

Phenothiazines and Butryrophenones

A

Anti-psychotic drugs with anti-emetic property

24
Q

Sucralfate

A

Protection

25
Q

Methyl analog of PGE1

A

Misoprostol, Protective agents

26
Q

Bismuth subsalicylate

A

Protective agents

*Traveler’s diarrheal

27
Q

Bismuth citrate

A

Protective agents

28
Q

Loperamide (Non-P,D)

A

Opioid agonist, Anti-diarrheal

29
Q

Diphenoxylate (P, ID)

A

Opioid agonist, Anti-diarrheal

30
Q

Traveler’s diarrhea

A

Bismuth subsalicylate

31
Q

Somatostatin

A

14-amino-acid peptide, ANTI-DIARRHEAL

32
Q

Cholestyramine
Colestipol
Colesevelam

A

Bile salt, anti-diarrheal

33
Q

Baking soda, Alka Seltzer

A

Sodium bicarbonate, antacids

34
Q

Tums, Os-cal

A

Calcium carbonate, antacids

35
Q

What are the examples of Sodium carbonate?

A

Baking Soda, LAlka seltzer

36
Q

What are the examples of calcium carbonate?

A

Tums, Os-cal

37
Q

Cimetidine, Ranitidine, Famotidine

A

H2 antagonist, Antacids

38
Q

omeprazole, Iansoprazole, Dexiansoprazole, rabeprazole, pantoprazole

A

PPI, antacids

39
Q

Commonly prepared from plant products and synthetic fibers

A

Bulk, laxatives

40
Q

Common agents are docusate and glycerin suppository

A

Softeners

41
Q

Common component in osmotic laxative?

A

Magnesium hydroxide

42
Q

Sorbitol, lactulose

A

Nonabsorbable sugar/salt (osmotic)

43
Q

Anthraquinone derivative (PEG)

A

Senna, Aloe, Cascara

44
Q

a 5-HT3 antagonist that treats severe IBS with diarrhea

A

Alosetron

45
Q

treats women with IBS with predominant constipation

A

Lubiprostone

46
Q

Scopolamine is a?

A

H1 antagonist in antiemetic section

47
Q

Malabsorption of bile salts leads to diarrhea

A

Cholestyramine, Colesevalam, Colestipol

48
Q

an H2 antagnost in antacid

A

Cimetidine

49
Q

Prepared from plant products and synthetic fibers; leads to flatus

A

Bulk-forming laxative

50
Q

Methylnaltrexone and alvimopan is a?

A

inhibits peripheral m-opioid receptors

PHA 037 - PHARMACOLOGY (19 decks)

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