schizophrenia Flashcards

(50 cards)

1
Q

what is schizophrenia?

A

Means a split mind
A mental disorder associated with disconnected thought processes and a loss of contact with reality
Characterised by a profound disruption of cognition and emotion
More commonly diagnosed in men and working class

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

classification of schizophrenia

A

Internal classification of disease (ICD-10)
Diagnostic and statistical manual (DSM-5)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

positive symptoms

A

Additional experiences beyond those of ordinary existence
Hallucinations
delusions
speech disorganisation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hallucinations

A

unusual sensory experiences
Can be any sense

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

delusions

A

Irrational beliefs that seem real
Delusions of Grandeur - important historical figures
Delusions of paranoia - victim of conspiracy(gov)
Delusions of control - under external control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Speech disorganisation

A

DSM5
Incoherent speech/topic change changes mid sentence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

negative symptoms

A

Reduction/loss of usual abilities and experiences
avolition
Speech poverty

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

avolition

A

inability to persist in goal director behaviour
Severe loss in motivation for every day tasks
Poor hygiene
Extreme = catatonic state

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

speech poverty

A

Mountain quality of speech is reduced
Delay in responses
ICD10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

differences between DSM 5 and ICD 10

A

DSM5 - one or more positive symptoms to diagnose
Remove subtypes in 2013
Speech disorganisation

ICD10 - 2 or more negative symptoms to diagnose
Still has subtypes
Speech poverty

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

inter-rated reliability

A

The extent to which two psychiatrists arrive at the same diagnosis for the same patient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

evaluation of diagnosing

A

Supporting evidence , high reliability and diagnosis of schizophrenia, strong positive correlation for schizophrenia diagnosis using DSM 5
Schizophrenia is comorbid with depression and 50% of cases which is confusing for psychiatrist
Overlapping symptoms of schizophrenia and bipolar so hard to distinguish diagnosed and treat
Contradictory evidence, low reliability and diagnosis. Two psychiatrist asked to diagnose 100 patients 44 diagnosed schizophrenia with the ICD 26 with DSM no consistency
Low validity of schizophrenia diagnosis another experiment and much more likely to be diagnosed using ICD which questions appropriateness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

comorbidity

A

When two or more conditions occur together at the same time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

symptom overlap

A

Similarity between symptoms and other conditions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

biological explanations - genetic factors

A

MZ - 100% shared genes
DZ - 50% shared.
aetiologically heterogeneous - different genes causing same disorder
Polygenic 108 genes
Family studies - gottesman - aunts 2% siblings 9%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

candidate genes - ripke et al

A

Metanalysis and found 108 different genetic variations associated with schizophrenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

evaluation of genetic factors

A

Only 48% in MZ twins, therefore Jean alone isn’t an explanation
Nature versus nurture shared some same genes but due to environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

dopamine

A

A neurotransmitter that has an excitatory effect and involved in sense of pleasure/reward

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Neural correlates

A

Patterns of activity in the brain that occur at the same time as an experience

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

hyperdopaminergia in the sub cortex

A

High levels of dopamine in the centre of brain original theory

22
Q

hypodopaminergia in the prefrontal cortex

A

more recent. Focused on abnormal dopamine systems in the brain.
goldman found role for low levels in PFC thinking and decision-making

23
Q

neural correlates of negative symptoms

A

Motivation involves anticipation of reward. Brain area for this is the ventral striatum.
Abnormality in VS = avolition
jackal found lower levels of activity in VS of SZ patients and a negative correlation

24
Q

Neural correlates of positive symptoms

A

allen scanned brains of people having hallucinations
lower activity levels in superior temporal gyrus and anterior cingulate gyrus
Reduced activity in these two brain areas is a neural correlate for auditory hallucinations

25
evaluation of the dopamine hypothesis and neural correlates
Supporting research for the role of dopamine - dopamine agonist like amphetamines make SZ worse. Antipsychotic drugs reduce symptoms which reduced dopamine suggesting dopamine is involved in increasing validity. Dopamine alone is questioned as brain scanning studies found increased levels of glutamate Research into neural correlate is issue of causing effect - juckel found negative correlation Contradictory evidence on the role of drug treatments antipsychotics that affect dopamine levels don’t benefit all SZ sufferers,
26
Psychological explanations
Family dysfunction
27
The schizophrenic mother
Psychodynamic explanation based on SZ patient childhood experience experiences SZ mother is SZ causing Cold rejecting lead to distrust and paranoid delusions
28
Double bind theory
Family climate important Role of communication style Child fears doing wrong thing and feels unable to comment on unfairness Child punished by withdrawal of love
29
expressed emotion
Negative emotion towards S said person Increase verbal criticism, violence, anger, and emotion over involvement High levels of EE leads to stress and an explanation for relapse or onset of SZ
30
cognitive explanations
Focuses on the role of mental processes in SZ Dysfunctional thoughts and information processing Characterised by disruption to normal thought processing
31
frith et al
identified two types of dysfunctional thought processing that could underline SZ symptoms meta representation and central control
32
meta representation
The cognitive ability to reflect on thoughts and behaviours Allows us insight into our own intentions and interpret others actions Dysfunction in meta representation would disrupt our ability to recognise own thoughts This explains hallucinations of voices
33
Central control
Suppress automatic response while performing actions instead disorganise speech could be from this inability Each word triggers associations and cannot stop automatic responses to these
34
evaluation of family dysfunction theories
Like a validity in research if supports informal research assessment with no systematic evidence unsure of true relationship Social socially sensitive research leads apparently blaming
35
evaluation of cognitive explanations
Limited at origin ignored proximal currently unclear how it leads to it only partial explanation Issue of causing effect research says dysfunctional thought process and occurs before the onset not a cause fact but maybe an effective abnormal brain functioning
36
typical antipsychotics
Used since the 1950s Main drug - chloroprozamine. Tablets/syrup daily max 1000mg. Gradual increase of dosage injections Works by blocking dopamine receptors
37
atypical antipsychotic
clozapine: used since 1980s as a last resort. 300-450mg a day. Vines to do for me and receptors and also acts on serotonin and glutamate receptors to decrease their action. risperidone: 1990s. Without clozapine’s side-effects 4 to 8 mg binds to dopamine and serotonin more effective.
38
evaluation of drug therapy
Practical applications less time off work benefits the economy Lack of vivid in research as most studies are short-term effects only Likelihood of side-effects, dizziness, delirium blood disorder Based on original dopamine hypothesis which is problematic as ineffective for low dopamine patients Appropriate nurse is questioned as doesn’t treat the cause risk of relapse after course stopped
39
psychological therapy-cognitive behavioural therapy
five and 20 sessions helps and identify rational thoughts and try to change them discussion of how likely believes are to be true and other less threaten possibilities helped to cope with symptoms make sense of how their delusions can affect their emotions and actions decreases anxiety normalisation also used explaining that it’s normal delusional challenge to learn not based on reality and provided with strategies to counter irrational thoughts self-distraction technique
40
evaluation of CBT
CBT now recommended by NICE validity for use Questionable quality of supporting evidence as small scale studies and lack of control group so difficult to know how effective with each person unique Not a cure a management technique improves their quality of life Worth doing for patient and economy
41
Family therapy
Aim is to increase quality of communication and interaction between family members
42
pharoah
range of strategies to improve family functioning: For a therapeutic alliance with all family members Decrease the stress of caring for a SZ relative Improving ability of the family to anticipate and solve problems Decrease of anger and guilt and family members Help family achieve balance between caring and maintaining own lives
43
burbach: model of practice
phases 1&2 - share information and identify resources families can offer phases 3&4 - learn mutual understanding look at unhelpful patterns of interaction phases 5,6&7- skills, training stress managing techniques
44
evaluation of family therapy
Benefits the whole family Quality of support and evidence questioned as small scale and lack of control Not a cure only manageable Benefits economy
45
Differences
amount of sessions recommended Who is involved? How it works
46
similarities
Both help to manage symptoms, not cure Both benefit economy Both teach techniques
47
token economy
Reward systems to manage behaviour mason - three categories of behaviour personal care condition related to behaviour and social behaviour Tokens given after desirable behaviour swap for actual rewards based on operant conditioning
48
evaluation of using token economy to manage schizophrenia
glowacki - identified seven studies on effectiveness and all showed a decrease in negative symptoms and decline in frequency of undesirable behaviour Evidence is limited as only found seven studies so a small evidence base Doesn’t cure only managers Benefit economy Concerns as more available for those symptoms
49
treatment according to the interactionist model
Combining antipsychotic medication and psychological therapy turkington -
50
evaluation of the interactionist model
Oversimplistic Effectiveness of combining treatment Incomplete understanding as don’t know why and how symptoms appear and how vulnerability and stress produce them