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Flashcards in Scientist Names Deck (25)
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1

Christiane Nüsslein-Volhard

Identify all genes in zebrafish development. Early 1990's.

2

Edward Lewis

First systematic attempt to identify all genes involved in Drosophila development

3

Christiane Nüsslein-Volhard and Eric Wieschaus

Developed Lewis's studies for full understanding of genetic control in Drosophila, genetic control of early embryonic develpment

4

Sydney Brenner, Sir John Sulston and Robert Horvitz

Used nematode for genetic regulation of organ development and programmed cell death

5

Aristotle

First person to describe embryonic development

6

William Harvey

Epigenesis - physician to King James I and King Charles I

7

Antonie van Leeuwenhoek

Discovered spermatazoa in 1677

8

Nicolaas Hartsoeker

Sperm artist

9

Nicolas Malebranche

Suggested sperm contained all genetic info of future generations

10

Marcello Malpighi

First person to observe chick development under microscope -> chicks preformed in fertilised egg

11

Hans Driesch

Sea urchin embryos are capable of replacing parts that had been deleted -> embryonic regulation

12

August Weismann

Zygote nucleus contained a number of special factors called determinants

13

Wilhelm Roux

Frog egg was a mosaic of different cell determinants

14

Edwin Conklin

Development of the differently coloured cytoplasm in larvae

15

Laurent Chabry

Each blastomere was responsible for producing a particular set of larval tissues (even in isolation)

16

Hiroki Nishida and Kaichiro Sawada

RNA hybridisatioin to identify maternal mRNAs that are localised to the vegetal hemisphere of ascidian eggs

17

Hans Spemann

Regulative development in 2 cell newt embryo

18

Pieter Nieuwkoop

Mesoderm induction occurs during blastula stages induced in animal fragment by vegetal fragment in axoloti and xenopus laevis embryos

19

Ernst Hadorn

Imaginal discs in drosophila differentiate as expected

20

Hans Spemann

First SCNT theory

21

Robert Briggs and Thomas King

First successful cloning of an animal by SCNT, Leopard frog (Rana pipiens)

22

Steen Willadsen

First successful attempt to clone a mammal by SCNT- sheep embryo

23

Keith Campbell and Ian Wilmut

Dolly

24

Harold Weintraub

Transdifferentiation

25

Kazutoshi Takahashi and Shinya Yamanaka

Oct4, Sox2, Myc and Klf4 sufficient to induce pluripotency