Semester 2 Exam II Drugs Flashcards

(110 cards)

1
Q

Levodopa

A

Dopaminergic agent; precursor in dopamine synthesis, crossed BBB

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2
Q

Carbidopa

A

Decarboxylation inhibitor (never monotherapy)

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3
Q

Carbidopa/levodopa (Sinemet)

A

Preferred Parkinson’s treatment

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4
Q

Bromocriptine

A

Ergot dopamine agonist

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5
Q

Ropinirole

A

Non-ergot dopamine agonist (Parkinson’s or restless leg)

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6
Q

Pramipexole

A

Non-ergot dopamine agonist (Parkinson’s or restless leg)

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7
Q

Selegiline

A

Monoamine oxidase type B inhibitor (always use with sinemet)

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8
Q

Rasagiline

A

Monoamine oxidase type B inhibitor (always use with sinemet)

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9
Q

Amantadine

A

Alternative to MAO-B inhibitor

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10
Q

Entacapone

A

COMT inhibitor (always with sinemet)

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11
Q

Tolcapone

A

COMT inhibitor (always with sinemet)

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12
Q

Pimavanserin

A

Atypical antipsychotic (only for Parkinson’s associated psychosis)

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13
Q

Tetrabenazine

A

VMAT-2 inhibitor (for chorea management)

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14
Q

Propranolol

A

Beta blocker (for essential tremor)

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15
Q

Atenolol

A

Beta blocker (for essential tremor)

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16
Q

Nadolol

A

Beta blocker (for essential tremor)

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17
Q

Metoprolol

A

Beta blocker (for essential tremor)

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18
Q

Primidone

A

Anticonvulsant (best choice for essential tremor)

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19
Q

Gabapentin

A

Anticonvulsant (essential tremor)

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20
Q

Topiramate

A

Anticonvulsant (essential tremor)

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21
Q

Interferon beta-1a

A

Interferon (MS) (SC)

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22
Q

Interferon beta-1b

A

Interferon (MS) (SC)

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23
Q

Glatiramer acetate

A

Immunomodulator for MS (daily SC)

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24
Q

Fingolimod

A

Immunomodulator for MS (PO)

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25
Teriflunomide
Immunomodulator for MS (PO)
26
Dimethyl fumarate
Immunomodulator for MS (PO)
27
Ocrelizumab
Monoclonal antibody for MS (IV)
28
Natalizumab
Monoclonal antibody for MS (IV)
29
Penicillin VK
Naturally occurring penicillin (beta lactam)
30
Penicillin G
Naturally occurring penicillin (beta lactam)
31
Amoxicillin
Aminopenicillin (beta lactam)
32
Amplicillin
Aminopenicillin (beta lactam)
33
Dicloxacillin
Penicillinase-resistant penicillin (beta lactam)
34
Nafcillin
Penicillinase-resistant penicillin (beta lactam)
35
Oxacillin
Penicillinase-resistant penicillin (beta lactam)
36
Piperacillin
Antipseudomonal penicillin (beta lactam)
37
Ampicillin/subactam
Beta-lactamase/penicillin combo
38
Amoxicillin/clavulanic acid
Beta-lactamase/penicillin combo
39
Piperacillin/tazobactam
Beta-lactamase/penicillin combo (antipseudomonal) - Zosyn
40
Ticarcillin/clavulante
Beta-lactamase/penicillin combo (antipseudomonal)
41
Cefazolin, Cephalexin, Cefadroxil
1st generation cephalosporins (beta lactam)
42
Cefaclor, Cefprozil, Cefuroxime, Lorbacef, Cefotetan, Cefoxitin
2nd generation cephalosporins (beta lactam)
43
Cefdinir, Cefixime, Cefpodoxime, Ceftibuten, Cefoperazone, Cefotaxime, Ceftriaxone, Ceftizoxime
3rd generation cephalosporins (beta lactam)
44
Ceftazidime
3rd generation cephalosporin (beta lactam) - with pseudomonas coverage
45
Cefepime
4th generation cephalosporin (beta lactam)
46
Ceftaroline
5th generation cephalosporin (beta lactam)
47
Ceftazidime/avibactam
Cephalosporin/beta-lactamase combo
48
Ceftolozane/tazobactam
Cephalosporin/beta-lactamase combo
49
Ertapenem
Carbapenem (beta lactam)
50
Imipenem/cilastatin
Carbapenem (beta lactam)
51
Meropenem
Carbapenem (beta lactam)
52
Doripenem
Carbapenem (beta lactam)
53
Meropenem/vaborbactam
Carbapenem/beta-lactamase inhibitor
54
Aztreonam
Monobactam (beta lactam)
55
Vancomycin
Glycopeptide
56
Dalbavancin
Glycopeptide
57
Telavancin
Glycopeptide
58
Oritavancin
Glycopeptide
59
Doxycycline
Tetracycline
60
Minocycline
Tetracycline
61
Tetracycline
Tetracycline
62
Tigecycline
Tetracycline
63
Omadacycline
Tetracycline
64
Eravacycline
Tetracycline
65
Ciprofloxacin
Fluoroquinolone
66
Levofloxacin
Fluoroquinolone
67
Moxifloxacin
Fluoroquinolone
68
Ofloxacin
Fluoroquinolone
69
Delafloxacin
Fluoroquinolone
70
Azithromycin
Macrolide
71
Clarithromycin
Macrolide
72
Erythromycin
Macrolide
73
Clindamycin
Clindamycin (prevent tRNA binding to 50s subunit)
74
Metronidazole
Metronidazole (inhibits DNA synthesis by causing strand breakage) - C. diff tx. (Flagyl)
75
Sulfamethoxazole/trimethoprim
Bactrim; sulfamethoxazole --> dihydropteroate synthase, trimethoprim --> dihydrofolate reductase
76
Amikacin
Aminoglycoside
77
Gentamicin
Aminoglycoside
78
Tobramycin
Aminoglycoside
79
Plazomicin
Aminoglycoside
80
Nitrofurantoin
Nitrofurantoin (destroy bacterial DNA and ribosomal proteins)
81
Linezolid
Oxazolidinone
82
Tedizolid
Oxazolidinone
83
Daptomycin
Daptomycin ("punches holes in membrane" binds with calcium and inserts in membrane --> K efflux)
84
Rifampin
Rifampin (inhibits RNA polymerase)
85
Fosfomycin
Fosfomycin (inhibits MurA enzyme) - one time dose, only for UTI
86
Fidaxomicin
Fidaxomicin (binds RNA polymerase, prevents transcription) - C diff tx
87
Terbinafine
Allylamine
88
Butenafine
Allylamine
89
Naftifine
Allylamine
90
Amorolfine
Allylamine
91
Ketoconazole
Imidazole azole
92
Clotrimazole
Imidazole azole
93
Miconazole
Imidazole azole
94
Econazole
Imidazole azole
95
Mebendazole
Imidazole azole
96
Oxiconazole
Imidazole azole
97
Sertaconazole
Imidazole azole
98
Sulconazole
Imidazole azole
99
Thiabendazole
Imidazole azole
100
Fluconazole
Triazole azole
101
Itraconazole
Triazole azole
102
Voriconazole
Triazole azole
103
Posaconazole
Triazole azole
104
Isavuconazole
Triazole azole
105
Nystatin
Polyene
106
Amphotericin B
Polyene
107
Caspofungin
Echinocandin
108
Micafungin
Echinocandin
109
Anidulafungin
Echinocandin
110
Flucytosine
Converted to 5-florouracil by fungi (not monotherapy)