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Flashcards in Serotonin Deck (15)
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1

Serotonin agonists (4 drugs/groups)

Bispirone
Triptans
Ergot drugs
Tegaserod

2

Triptans (1 drug)

Sumatriptan

3

Serotonin agonists used for migraine headache

Triptans (e.g. sumatriptan)
Ergot drugs

4

Bispirone - indications, which serotonin receptor is activated?

Anxiety, depression
5-HT1A-receptors

5

Activation of which serotonin receptors is useful in migraine treatment?

5-HT1D/1B

6

Serotonin antagonists (7 drugs)

Clozapine, cyproheptadine, ondasetron, ganisetron, alosetron, palonosetron, dolasetron

7

Clozapine - indications

Schizophrenia

8

Which serotonin antagonist has antihistamine activity?

Cyproheptadine

9

Cyproheptadine - indications

Allergic reactions
Carcinoid tumor

10

Which serotonin antagonists are 5-HT2 antagonists? (2 drugs)

Clozapine
Cyproheptadine

11

Which serotonin antagonists are selective 5-HT3 receptor antagonists? (5 drugs)

Ondasetron
Ganisetron
Alosetron
Palosetron
Dolasetron

12

The 5-HT3 antagonists have which effect in CNS?

Blocks serotonin in chemoreceptor trigger zone

13

Alosetron - indications

Women with IBS with diarrhea

14

Serotonin antagonists used as antiemetics (3 drugs)

Ondasetron
Ganisetron
Palosetron

15

Serotonin reuptake inhibitors are used in?

Depression + CNS disorders