Serotonin Flashcards Preview

Pharmacology > Serotonin > Flashcards

Flashcards in Serotonin Deck (13):
1

CYPROHEPTADINE

Targets 5-HT2A
Also a muscarinic H1 antagonist
Treat Carcinoid Syndrome and cold-induced urticaria

2

Targets 5-HT2A and Alpha Adrenergics
Block sm contraction and platelet aggregation
Not approved for US use

KETANSERIN

3

TRIPTANS

Agonist - Targets 5-HT1B/D
Prevent vasodilation and stretching of pain fibers, Inhibit pro-inflammatory molecules

4

Targets 5-HT3
(Zofran) Post-surgical/chemo anti-emetic

ONDANSETRON, GRANISETRON

5

BUSPIRONE

Agonist - Targets 5-HT1A
Anxiolytic

6

CLOZAPINE

Targets 5-HT7
(And Dopamine receptors)
Atypical antipsychotic

7

KETANSERIN

Targets 5-HT2A and Alpha Adrenergics
Block sm contraction and platelet aggregation
Not approved for US use

8

Targets 5-HT7
(And Dopamine receptors)
Atypical antipsychotic

CLOZAPINE

9

Agonist - Targets 5-HT1A
Anxiolytic

BUSPIRONE

10

ONDANSETRON, GRANISETRON

Targets 5-HT3
(Zofran) Post-surgical/chemo anti-emetic

11

Agonist - Targets 5-HT1B/D
Prevent vasodilation and stretching of pain fibers, Inhibit pro-inflammatory molecules

TRIPTANS

12

Targets 5-HT2A
Also a muscarinic H1 antagonist
Treat Carcinoid Syndrome, Cold-induced urticaria, Serotonin Syndrom

CYPROHEPTADINE

13

Triphasic Response of Serotonin

Decrease BP/CO/HR, Increase BP, Decrease BP