Session 2 - Embryology of H&N Flashcards

(35 cards)

1
Q

At what week do pharyngeal arches develop?

A

4

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2
Q

How many pharyngeal arches are there? What are they numbered?

A

1-6, 5 pharyngeal arches. Number 5 is obliterated.

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3
Q

What 3 structures does each pharyngeal arch have associated with it?

A

Artery, nerve, and cartilage bar

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4
Q

Describe the formation of the nerual tube

A
  • Notochord signals cause overlying ectoderm to thicken
  • Edges elevate out of plane of the disk and curl towards each other, creating the neural tube.
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5
Q

What part of the neural tube forms the brain?

A

anterior end

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6
Q

Name the 4 functional regions of the neural tube

A
  • Prosencephalon = forebrain
  • Mesencephalon = midbrain
  • Rhombencephalon = hindbrain
  • Spinal cord
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7
Q

How many cranial nerves are there? Which cranial nerves are derived in the forebrain?

A

12 cranial nerves

1 and 2 derived in forebrain

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8
Q

What is the facial skeleton derived from?

A

Frontonasal prominence and 1st PA

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9
Q

Where are the muscles of mastication derived from?

A

PA1

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10
Q

Where are the muscles of facial expression derived from?

A

PA2

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11
Q

What are the derivatives of PA1 and 2?

A

1 - Facial skeleton and muscles of mastication

2 - Muscles of facial expression

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12
Q

What are the derivatives of PA 3 and 6?

A

3 - stylopharyngeus

6 - Intrinsic muscles of the larynx

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13
Q

What are the derivates of PA4?

A

Cricothyroid, levator palatini, constrictors of the pharynx

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14
Q

What is the name of cranial nerve:

a) V
b) VII
c) IX
d) X - 4th PA
e) X - 6th PA

A

a) trigeminal
b) Facial
c) glossopharyngeal
d) superior laryngeal
e) recurrent laryngeal

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15
Q

What are the sensory and motor innervations of CN V?

A

Sensory - Skin of face, lining of nose and mouth

Motor - Muscles of mastication, muscles derived form mandibular process

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16
Q

What are the sensory and motor innervations of CN VII?

A

Sensory - Taste buds in Anterior 2/3 of tongue

Motor - Muscles of facial expression, muscles derived from PA2

17
Q

What are the sensory and motor innervations of CN IX?

A

Sensory - Posterior 1/3 of tongue

Motor - Stylopharyngeus muscle

18
Q

What are the sensory and motor innervations of CN X (PA4)?

A

Motor innervation - cricothyroid, constrictors of pharynx

19
Q

What are the sensory and motor innervations of CN X (PA6)?

A

Motor - Intrinsic muscles of the pharynx

20
Q

What are the cartilage bars derived from PA1, 2, 4, and 6?

A

PA 1 - Meckels

PA 2 - Reicherts

PA 4 and 6 - Cartilages of larynx

21
Q

What does the cartilage bar of PA1 develop into?

A
  • PhA1 divides into maxillary and mandibular prominences
  • Mandibular prominence develops the Meckel’s cartilage, composed of the Malleus and incus which provides a template for mandible formation via membranous ossification
22
Q

What does PA2 cartilage bar develop into?

A
  • Contributes to middle ear development via stapes
  • Forms the styloid process and hyoid bone
23
Q

What does the cartilage bar of the 4th and 6th PA devleop into?

A
  • Mesenchyme of 4th and 6th arch forms the epiglottis
  • Cartilage bars of 4th and 6th forms the thyroid, arytenoid, and cricoid cartilages
24
Q

What does the PA3 cartilage bar develop into?

A
  • Hyoid bone (great cornu and lower body)
25
What are the arterial derivatives of PA 1-6?
1-3 - common, internal and external carotid arteries and branches 4 - Aortic arch and part of right subclavian 6 - pulmonary arteries
26
Where does the aortic sac lie?
floor of the pharynx
27
What are the pharyngheal pouches? How many pairs do we have?
* Form on the endodermal side between the pharyngeal arches * These form the lateral ectodermal surface of the neck region * 4 pairs
28
What does the 1st pharyngeal pouch become?
Eustachian tube and middle ear cavity
29
What does the 2nd pharyngeal pouch become?
Crypts of palatine tonsil
30
What does the 3rd pharyngeal pouch become?
* Divides into dorsal and ventral * Dorsal part - inferior parathyroid * Ventral part - thymus
31
What does the 4th pharyngeal pouch become?
* Divides into dorsal and ventral part * Dorsal - Superior parathyroid * Ventral - Thyroid C cells
32
From where are the ossicels of the middle ear derived?
Meckels and reicherts
33
How many pharyngeal clefts are there and why?
Only 1st cleft remains as the 2nd arch grows down to cover the others.
34
What could happen if the cervical sinus is not obliterated?
cysts or fistulae can occur anywhere along anterior border of SCM
35