Signal Transducers, Transcription Factors, and Cyclins w/ Associated Cancers Flashcards

1
Q

RAS

A

Pancreatic adenocarcinoma, colon, endometrial, lung, and thyroid cancers

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2
Q

NF1

A

Familiar neurofibromatosis type 1

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3
Q

BRAF

A

Hairy cell leukemia, melanoma, non-Hodgkin lymphoma

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4
Q

PTEN

A

Prostate, breast, endometrial

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5
Q

BCR-ABL

A

Chronic myeloid leukemia, ALL

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6
Q

JAK2

A

Polycythemia vera, essential thrombocytosis

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7
Q

MYC

A

c: Burkitt lymphoma, breast carcinoma
n: Neuroblastoma
l: Lung carcinoma

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8
Q

CDKN2A (p16)

A

Many cancers

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9
Q

CDK4

A

Melanoma

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10
Q

CCND1/cyclin D1

A

Mantle cell lymphoma

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