Sjogren Syndrome Flashcards
(13 cards)
What is Sjogren Syndrome?
idiopathic autoimmune disorder secondary to Ab against lacrimal and salivary glands
What conditions is Sjogren’s strongly associated with?
RA
SLE
Primary Biliary Cirrhosis (PBC)
Polymyositis
Hashimoto Thyroiditis
What are common symptoms of Sjogren Syndrome?
Joint pain
Dry eyes and mouth
Feeling of sand in the eyes and itching: Keratoconjunctivitis Sicca
Loss of vaginal secretions: Dyspareunia
What are some of the less common symptoms seen in Sjogren Syndrome?
Vasculitis
Lung Disease
Pancreatitis
Renal Tubular Acidosis
What is the best initial test for Sjogren?
Schirmer test
What is the most accurate test for Sjogren?
Lip or parotid gland biopsy: showing lymphoid infiltration in the salivary glands
What is the best initial blood test for Sjogren?
SS-A and SS-B
What is seen on Rose Bengal Stain in Sjogren?
Abnormal Corneal Epithelium
What Ab are most specific for Sjogren?
SS-A and SS-B
What is the best initial treatment for Sjogren?
Hydrate the mouth
What can be used to avoid corneal ulcers in Sjogren?
Artificial tears
What can be used to reduce ocular inflammation in Sjogren?
Topical LIfitegrast or Cyclosporine
What can be used to increase saliva production in Sjogren?
Pilocarpine and Cevimeline: they increase Ach to stimulate production
