Skeletal Muscle And Nerve Tissue Histo Flashcards

(43 cards)

1
Q

Skeletal muscle

A
Striated 
Multinucleated
Fatigable 
Voluntary
Quick
Strong
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2
Q

Myofiber

A

A group of myofibrils surrounded by endomysium
Muscle Cell
Myocyte

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3
Q

Myofibrils

A

Groups of sarcomeres

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4
Q

Sarcomeres

A

Contractile group made of actin and myosin myofilaments

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5
Q

Actin

A

Thin filaments
Made of f-actin monomers
Monomers come together to form actin filaments (in double stranded rings)
Uses nebulin to determine length of filament
Tropomyosin is intertwined in actin filament
Troponin is bound to tropomyosin blocking the myosin binding site

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6
Q

Myosin

A

Thick filaments
Has 2 heavy chains and 2 light chains
Heavy chains contain ATPase domain, actin binding sites, and myosin heads
Connected to Z disk via titin

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7
Q

Fascicle

A

Group of myofibers

Surrounded by perimysium

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8
Q

Muscle

A

Group of fascicles

Surrounded by epimysium

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9
Q

Sequence of what makes a muscle

A
Myosin and actin myofilaments
Sarcomere
Myofibril
Myofiber
Fascicle
Muscle cell
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10
Q

Z disk

A

Sarcomere is Z disk to Z disk

Contains actin and myosin

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11
Q

M line

A

Where myosin attaches

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12
Q

H zone

A

Contains no thin filaments

Changes size during contraction

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13
Q

I band

A

Contains no myosin

Changes size during contraction

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14
Q

A band

A

From the end of one myosin head to the end of an adjacent myosin head
Does not change size during contraction

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15
Q

Muscle Contracttion

A

Ca2+ is released by the sarcolemma and binds to troponin
Causes conformational change
Troponin lets go of tropomyosin
Myosin binds to actin and crawls across actin
Myosin and actin do NOT change size
H zone and I band shorten
Z disk to Z disk becomes closer
all myofibrils in a muscle contract at the same time making the entire muscle shorten

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16
Q

Skeletal muscle fiber types

A

Type I
Type IIa
Type IIb

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17
Q

Type I muscle fiber

A
Slow, not very powerful
Many mitochondria
Great deal of myoglobin
Aerobic respiration
Slow fatiguability
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18
Q

Type IIA muscle fiber

A
Intermediate speed and power
Many mitochondria
Many myoglobin
Intermediate fatiguability
Aerobic respiration (less O2 necessary than type I)
19
Q

Type IIb muscle fiber

A
Quick, very powerful
Few mitochondria
Few myoglobin
Quick fatiguability 
Anaerobic respiration
20
Q

Sarcolemma

A

Membrane surrounding muscle cell

21
Q

Transverse (T) tubule

A

Perforated muscle cells so electrical transmission can go from sarcolemma to muscle cell

22
Q

Sarcoplasmic Reticulum (SR)

A

Acts as a smooth ER for muscle cells
Has terminal cisternae
Holds Ca2+

23
Q

Terminal cisternae

A

Flattened sac of SR on either side of a T tubule

24
Q

Triad

A

T tubule and 2 terminal cisternae (one on each side)

25
End feet
Connect T tubules with SR to allow Ca2+ release
26
Neuromuscular junction
Skeletal muscle innervated by alpha motor neurons from anterior horn of spinal cord 1 nerve per muscle cell 1 nerve can supply many muscle cells
27
Extrafusal fibers
Part of neuromuscular spindle apparatus | Contract muscles
28
Neuromuscular spindle appparatus
Reflexive response preventing overstretching of muscle
29
Intrafusal fibers
Sense length change in muscle fibers | Inside extrafusal fibers
30
Type Ia sensory muscle fibers
Afferent innervation in intrafusal fibers | Send signals to extrafusal and intrafusal muscle fibers
31
Alpha motor neurons
Efferent fibers from anterior horn of spinal cord causing contraction of extrafusal muscle fibers
32
Gamma motor neurons
Efferent neurons from anterior horn causing contraction of intrafusal muscle fibers
33
Soma/body of neuron
Contains all neuron organelles
34
Nissle substance
Abundant ribosomal ER in cytoplasm of soma/body of neurons
35
Dendrites
Receive signals from other neurons
36
Axon hillock
Connect soma/body with axon | Accumulates all electrical signals from dendrites to send them down the axon
37
Axon
Sends electrical signals from neuron to synapse
38
Synapse
Transfers electrical impulse from the neuron to the target tissue
39
Neuron types
Multipolar Bipolar Psueodunipolar
40
Multipolar
Multiple dendrites and one axon
41
Bipolar
1 dendrite (multiple extensions) and 1 axon
42
Pseudounipolar
1 dendrite and 1 axon, but cell body is separated from both
43
Myelination
Schwann cells-PNS Oligodendrocytes-CNS Transmits electrical signal faster