Skin Flashcards

1
Q

what is panniculitis?

A

inflamm of subcutaneous tissue

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2
Q

what is adnexal?

A

sweat glands, hair, sebaceous glands

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3
Q

where are sweat glands in the skin?

A

dermis and hypodermis

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4
Q

where are hair follicle in the skin?

A

dermis and hypodermis

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5
Q

5 layers of epidermis?

A
Stratum: Basale
Spinosum
granulosum
lucidum
corneum
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6
Q

what does the stratum spinosum look like ihstologically?

A

intercelullar bridges with desmosomal junctions

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7
Q

why is dermo-epidermal junction tortuous?

A

increase surface area to minimize sloughing of epidermis during shear forces

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8
Q

what is dermal papilla

A

outcropping of dermis into epidermis

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9
Q

main cells in the epidermis?

A

keratinocytes

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10
Q

what is epidermal rete ridge?

A

outcropping of epidermis into dermis

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11
Q

what attaches from keratinocyte to basement membrane?

A

hemi-desmosome

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12
Q

how long for a basal cell epidermal life cycle?

A

60 days

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13
Q

ratio of melanocytes to keratinocytes

A

1:10

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14
Q

melanocyte structure? where is it?

A

between basal cells

large cytoplasmic processes extend up between keratinocytes

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15
Q

purpose of melanocytes?

A

make melanin to protect keratinocytes’ nuclei against UV

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16
Q

3 things determine skin colour

A

genetics
sun exposure
blood flow

17
Q

what are Langerhans cells of the epidermis?

A

antigen presenting cells active in contact dermatitis and other neoplastic lesions

18
Q

what kind of cells are Merkel Cells ?

A

neuro-endocrine cells

active in touch

19
Q

what are the 2 main layers of dermis? collagen?

A
  1. Papillary - fine collagen with elastic

2. reticular - coarse collagen

20
Q

what do papillary and reticular dermis both contain?

A

macrophages APCs

21
Q

what surrounds sweat glands?

A

myoepithelial cells to contract

22
Q

muscles around hair called?

A

erector pili

23
Q

sebaceous glands empty into?

A

hair follicles

24
Q

what kind of sweat glands in armpits?

A

apocrine sweat glands

25
Q

how to temp regulate in skin?

A

change the arteriovenous anatomosis levels

26
Q

where are the free nerve endings in skin?

A

epidermis

27
Q

what kid of skin in hands and feet?

A

thick skin glaberous

more keratin, no hair follicles, yes sweat glands

28
Q

wound a few weeks old has?

A

granulation tissue

29
Q

healing by primary intention?

A

less scar
less granulation tissue
ends closer together

30
Q

healing by secondary intention? time? susceptibility?

A

takes longer

susceptible to infection and dehydration

31
Q

3 phases of healing?

A

inflamm
proliferation
maturation

32
Q

superficial burns affects?

A

epidermis only

33
Q

partial thikness affects?

A

epidermis + dermis varying

34
Q

full thickness burn affects?

A

full epidermis, dermis and variable subutaneous

35
Q

surgical incisions should be made where?

A

along cleavage lines to minimize scarring

36
Q

keloid scar is?

A

excessive collagen formation