Skin and Soft Tissues Flashcards Preview

Surgery PLE > Skin and Soft Tissues > Flashcards

Flashcards in Skin and Soft Tissues Deck (59):
1

What is the keratinocyte transit time

40 - 56 days

2

Factors that increase melanin production

1. uv radiation
2. estrogen
3. adrenocorticotropic hormone
4. melanocyte stimulating hormone

3

Also known as skin macrophages

langerhan's cell - produce MHC II

4

These are sweat producing glands located over the entire body but are concentrated in the palms, soles, axillae and forehead

eccrine glands

5

pheromone producing glands found in the axillae and anogenital region

appocrine glands

6

IVF extravasation is considered what type of burn

chemical burn

7

most common cause of extravasation in adults

chemotherapeutic drugs

8

most common site of extravasation in adults

dorsum of the hand

9

most common cause of extravasation in infants causing necrosis

high concentration dextrose

10

What causes pressure injury

1 hour of 60 mmHg pressure

11

Normal pressure values

arteriole - 32 mmHg
capillary - 20 mmHg
venule - 12 mmHg
Sitting - 300 mmHg
Hospital Bed - 150 mHg

12

Most important protective factor from UV related damage

melanin

13

most common form of radiation exposure

solar or uv radiation

14

treatment of cellulitis

oral antibiotics

15

treatment of folliculitis

adequate hygiene

16

treatment of furuncle

1.warm water to hasten liquefaction and rupture
2. incision and drainage

17

treatment of carbuncle

1. incision and drainage

18

It is a defect of the terminal follicular epithelium which leads to blockage of appocrine glands

hidradenitis suppurative

19

treatment of hidradenitis suppurative

acute - warm compress, antibiotics, open drainage
chronic - wide excision with closure using skin graft or local flap

20

It is a granulomatous suppurative bacterial disease and deep cutaneous infection that present as nodules and spread to form draining tracts. Pathognomonic is positive SULFUR granules within purulent specimen

actinomycosis

21

treatment of actinomycosis

penicillin or sulfonamide

22

It is a rapidly enlarginc, destructive, cutaneous necrotic lesion with undermined border and surrounding erythema; associated with a systemic disease 50% of the time

pyoderma gangrenosum

23

Histopathology reveals cleavage plane in the GRANULAR layer of the epidermis

SSS

24

Histopathology reveals structural defect at DERMOEPIDERMAL JUNCTION similar to a 2nd degree burn

SJS/TEN

25

Most common location of dermoid cyst

eyebrow
-results from trapping of epithelium during fetal midline closure

26

most common location of trichilemmal (pilar) cyst

scalp
-this cyst has NO granular layer

27

Another name for achrochordon

skin tags

28

usual location of dermatofibroma

legs and flanks

tx: excision

29

most common cutaneous lesion in infancy

hemangioma

30

Flat dull red lesion often located on the trigeminal distribution on the face trunk or extremities

capillary malformation/ port wine stain

assoc: sturge webber syndrome

31

this is associated w ith von recklinghausen 's disease

neurofibroma

32

These are solitary tumors arising from cells of the peripheral nerve sheath

neurileoma

33

These are neural tumors that are solitary lesions of the skin or more commonly of the tongue

granular cell tumor

34

most common type of skin cancer

basal cell carcinoma

35

most common type of basal cell carcinom

nodulocystic/noduloulcerative

36

characteristic lesion of the nodulocystic type of BCC

rodent ulcer - rolled, pearly borders surrounding a central ulcer

37

Treatment of basal cell carcinoma

1. <2 mm - curettage, electrodeiccation, laser vaporization
2. large tumors - surgical excision with 0.5 cm to 1 cm margin

38

Treatment of basal/squamous cell carcinoma located in the cheek, nose or lips

MOH's surgery

39

Where does basal cell carcinoma arise from

pluripotent basal epithelial cells of EPIDERMIS

40

Where does squamous cell carcinoma arise from

epidermal keratinocytes

41

name of in situ lesion of squamous cell carcinoma

1. bowens disease
2. erythroplasia of queyrat - penis

42

What are the ulcers called in burn scars

Marjolin's ulcer

43

treatment of squamous cell carcinoma

1. excision with 1 cm margin
2. regional LN excision if with palpable nodes or chronic wounds

44

Malignant melanoma arise from

melanocytes

45

what is the premalignant lesion of malignant melanoma

dysplastic nevi

46

most common location of malignant melanoma

skin

47

Subtypes of malignant melanoma

1. superficial spreading
2. nodular
3. lentigo maligna
4. acral lentiginous

48

Most common subtype of malignant melanoma

superficial spreading

49

Subtype of malignant melanoma with worse prognosis

acaral lentiginous

50

subtype of malignant melanoma with best prognosis

lentigo maligna

51

Treatment of malignant melanoma

1. melanoma in situ/lentigo maligna in face: 0.5 cm margin
2. 1 mm or less: 1 cm margin
3. 1 to 4 mm: 2 cm margin
4. more than 4 or (+) satellosis: 3 - 5 cm margin

52

It is a primary neuroendocrine carcinoma of the skin

Merkel Cell carcinom

53

Treatment of merkel cell carcinom

wide local resection with 3 cm margin + prophylactic LN dissection + adjuvant radiation

54

These are rubbery bluish nodules that occupy primarily on the extremities, skin and viscera

kaposi sarcoma

55

modulate cold sensation

krause' end bulb

56

modulate sensitivity to warmth

ruffini's endings

57

modulate sensation of pressure

pacinian corpuscle

58

modulate tactile sensation

meissner's corpuscles

59

modulate thermoregulation nerve

autonomic endings