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Human Disease AKA Nickey > Skin Diseases > Flashcards

Skin Diseases Flashcards

1
Q

What type of cell is skin?

A

Keratinized stratified squamous epithelium

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2
Q
A

Langerhans cell in skin ( brown parts )Histiocytes
Job is to recognize antigen

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3
Q

What is is acute Eczema?

A

Acute dermatitis

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4
Q
A

Acute eczema toys dermatitis
Edema/fluids splays keratinocytes and has a spongy look

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5
Q

Chronic Inflammatory dermatitis?

A

Psoriasis

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6
Q

Greek for Psoraisis?

A

The itch

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7
Q

what is Psoriasis?

A

CD4 and CD8 and growth factors
Hyper proliferation of the keratin

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8
Q

What is Ancanthosis?

A

Hyperplasia of the ancanthotic layer

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9
Q

What is parakeratosis?

A

Nucli come to the top of the skin

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10
Q
A

Psoriasis
The spines = ancanthosis
The nucli on top = parakeratosis

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11
Q

Greek for eczematous?

A

Boiling over

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12
Q

Seborrheic is what in Latin?

A

Tallow

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13
Q

What is seborrheic?

A

Barnacles on old people
Caused by fibroblast growth factor receptor
Never malignant

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14
Q

Verruca is Latin for what?

A

Wart

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15
Q

how do you get Verruca?

A

HPV
Cant become malignant
Undulant epidermal hyperplasia and koilocytosis (hollow)

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16
Q

How do you get acntinic Keratosis?

A

Sun exposure
Can regress to cancer
Basal cell hyperplasia

17
Q

Dermal solar elastosis is what?

A

Makes you skin wrinkly

18
Q
A

Actinic

19
Q

What is basal cell carcinoma

A

Most common human cancer
Rarely metastasizes
PTCH pathway dysregulation

20
Q
A

Basal cell carcinoma
Don’t grow up to be keratoniocies

21
Q

What is a Squamous cell carcinoma?

A

Sun exposure but also burns and ulcers
Also from immunosuppression
Worse than basal cell but 5% can metastasize

22
Q
A

Squamous cell carcinoma have keratin pearls

23
Q

What is melanoma?

A

Mutation in proto-oncogenes and tumor suppressor genes

24
Q

Where is melanoma worse?

A

New Zealand and and Australia bc Irish people

25
Q

What goes bad in Melanoma?

A

Melanocytes gone bad

26
Q
A

Melanoma

27
Q

What is the ABCDE rule

A

A is asymmetrical
B is border
C is color variation
D - diameter bigger than a pencil erase 6cm
E - evolution does it change overtime

28
Q
A

Melanoma

Human Disease AKA Nickey (8 decks)

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