Small Bowel Bacterial Overgrowth Syndrome Flashcards
What is small bowel bacterial overgrowth syndrome (SBBOS)?
It is defined as a condition in which there is increased amounts of bacterial in the small bowel
What are the six risk factors of small bowel bacterial overgrowth syndrome?
Congenital Gastrointestinal Abnormalities
Gastrointestinal Surgery
Crohn’s Disease
Diverticulosis
Diabetes Mellitus
Scleroderma
What are the six clincial features of small bowel bacterial overgrowth syndrome?
Nausea & Vomiting
Abdominal Pain
Abdominal Distension
Chronic Diarrhoea
Steatorrhoea
Weight Loss
What are the two investigations used to diagnose small bowel bacterial overgrowth syndrome?
Hydrogen Breath Test
Small Bowel Aspirate & Culture
What is the first line investigation used to diagnose small bowel bacterial overgrowth syndrome?
Hydrogen Breath Test
What is the hydrogen breath test?
It involves consumption of a high glucose containing liquid, which is broken down by anaerobic bacteria in the small intestine into hydrogen gas
After fifteen minutes, the volume of hydrogen exhaled is measured
What is a positive hydrogen breath test result?
Increased volumes of exhaled hydrogen
What is the gold standard investigation used to diagnose small bowel bacterial overgrowth syndrome?
Small Bowel Aspirate & Culture
What are the four features of small bowel bacterial overgrowth syndrome on small bowel aspirate and culture?
Bacterial Concentration > 103 CFUs/mL
Intestinal Villous Blunting
Thickened Lamina Propria
Epithelial Inflammation
What is the pharmacological management option of small bowel bacterial overgrowth syndrome?
Antibiotics
Name three antibiotics used to manage small bowel bacterial overgrowth syndrome
Rifaximin
Co-Amoxiclav
Metronidazole
What is the first line antibiotic used to manage small bowel bacterial overgrowth syndrome?
Rifaximin
