SNRIs Flashcards
1
Q
Desvenlafaxine (g)
A
Pristiq (b)
2
Q
Duloxetine (g)
A
Cymbalta (b)
3
Q
Venlafaxine (g)
A
Effexor (b)
4
Q
MOA
A
prevent the reuptake and maintaining levels of serotonin and NE in the neuronal synapse
5
Q
common adverse effects
A
similar to SSRIs (serotonin effect)
increased HR & BP
feeling excitable (much less sedation than SSRIs due to NE effect)
6
Q
rare adverse effects
A
hyponatremia
bleeding (additive risk with anticoags)
serotonin syndrome
7
Q
counseling pts
A
takes 1-2 weeks to feel a benefit, 6-8 weeks for full effect on mood.
take in AM
8
Q
clinical pearls
A
duloxetine can also be used for neurologic pain
