TCAs Flashcards

1
Q

Amitriptyline (g)

A

Elavil (b d/c)

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2
Q

Nortriptyline (g)

A

Pamelor (b)

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3
Q

MOA

A

inhibit reuptake of serotonin and NE (also block ACh and histamine receptors –> side effects)

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4
Q

common adverse effects

A

orthostasis, tachycardia
weight gain
dry mouth, blurred vision, urinary retention, constipation
major sedation

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5
Q

rare adverse effects

A

overdose can cause fatal arrhythmias (QT prolongation)
monitor for suicidal ideation

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6
Q

counseling pts

A

takes 1-2 weeks to feel benefit; 6-8 weeks for full effect on mood
take in PM

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