Specialty Flashcards
(105 cards)
1
Q
Benlysta
A
Belimumab
2
Q
Benlysta MOA
A
Inhibits B cell activation
3
Q
Benlysta indication
A
Lupus
4
Q
Benlysta typical dosing
Oral:
Self injection:
A
Twice daily
Once weekly SQ
5
Q
How long for results with Benlysta?
A
7 months
6
Q
Benlysta 5 common side effects
A
GI: Nausea, diarrhea, fever,
Upper resp: cough, sore throat, runny nose,
CNS: insomnia, pain, depression, headache, itching.
7
Q
Cetrotide
A
Cetrorelix
8
Q
Cetrotide MOA
A
GNRH antagonist that delays ovulation for egg retrieval procedure
9
Q
Cetrorelix route and frequency
A
SQ daily
10
Q
Cetrorelix 2 common side effects
A
Headache, nausea
11
Q
Avonex
A
Rebif
12
Q
Avonex MOA
A
Interferon
13
Q
Avonex indication
A
multiple sclerosis
14
Q
Avonex admin route
A
IM
15
Q
Rebif admin route
A
Sub Q every 48 hours
16
Q
Tocilizumab
A
Actemra
17
Q
Actemra
A
Tocilizumab
18
Q
Actemra MOA
A
IL-6 antagonist
19
Q
Actemra indication
A
Rheumatoid arthritis
20
Q
Actemra SQ admin
A
Allow to reach room temp 30 min syringe, 45 min autoinjector
21
Q
What should Actemra solution look like?
A
Clear to pale yellow
22
Q
Cosentyx
A
Secukinumab
23
Q
Cosentyx MOA and indication
A
IL-17 antagonist in psoriasis and psoriatic arthritis
24
Q
Cosentyx admin
A
Sub Q Allow to reach room temp 15 minutes sensoready pen or 30 minutes unoready pen.
25
Where to inject Cosentyx?
Front thigh, Lower abdomen, outer upper arms
26
Cosentyx 2 common side effects
Infection and sinus infection
27
Fasenra
Benralizumab
28
Benralizumab
Fasenra
29
Benralizumab MOA and indication
IL-5 antagonist, reduces survival of eosinophils and basophils, asthma
30
Fasenra admin
Allow to come to room temp for 30 minutes
31
Fasenra route
Sub Q, upper arm, thigh, or abdomen.
32
Leukeran
Chlorambucil
33
Chlorambucil
Leukeran
34
Leukeran MOA and indication
DNA alkylator, cancer
35
Leukeran 3 common side effects
Rash, blood dyscrasia’s, hepatotoxicity, pneumonitis
36
Kevzara
Sarilumab
37
Sarilumab
Kevzara
38
Kevzara MOA and indication
IL-6 antagonist, rheumatoid arthritis and psoriatic arthritis
39
Kevzara route
Sub Q thigh, abdomen, upper arm. Pre filled syringe warm for 30 minutes, pre filled pen warm for 60 minutes.
40
Kevzara appearance
Clear to pale yellow
41
Common side effects kevzara
Elevated AST /ALT, respiratory infection, UTI
42
Enbrel
Etanercept
43
Etanercept
Enbrel
44
Enbrel MOA and indication
TNF blocker for rheumatoid and psoriatic arthritis
45
Enbrel common side effects
Infection, rash, headache
46
Enbrel admin
Let autoinjector come to room temp for 30 min, sub Q in thigh, upper arm, or abdomen
47
Mekinist
Trametinib
48
Trametinib
Mekinist
49
Mekinist MOA and indication
Kinase inhibitor (targeted at cancer specific kinases that slows or stops growth of cancer cells)
50
Mekinist common side effects
Rash, diarrhea, nausea, fatigue, lymphedema
51
Trametinib admin
With small meal
52
Pregnyl
Chorionic gonadotropin
53
Pregnyl MOA
Induce ovulation and increase sperm count in men
54
Chorionic gonadotropin
Pregnyl
55
Pregnyl common side effects
Bloating, stomach pain
56
Pregnyl admin
Reconstitute, give IM in buttocks upper right quadrant.
57
Crinone
Progesterone
58
Crinone route
IM
59
Crinone indication
Abnormal uterine bleeding, infertility
60
Crinone common side effects
Bloating, abd pain, cramps, sleepy, mood swings, breast pain
61
Tasigna
Nilotinib
62
Nilotinib
Tasigna
63
Nilotinib indication
Leukemia
64
Common Tasigna side effects
Derm: balding, night sweats, itching, rash,
Kidneys: electrolyte discrepancy and swelling, high cholesterol and triglycerides, abd pain, all GI, myalgia, resp: cough, URTI, fatigue
65
Erleada
Apalutamide
66
Apalutamide
Erleada
67
Erleada MOA and indication
Androgen receptor antagonist, Prostate cancer
68
Erleada common side effects
HTN, swelling, rash, flushing, weight loss, nausea, diarrhea, joint pain, fatigue
69
Gleostine
Lomustine
70
Lomustin
Gleostine
71
Gleostine indication and MOA
Cancer, alkylating agent
72
Xeloda
Capecitabine
73
capecitabine
Xeloda
74
Cytoxan
Cyclophosphamide
75
Cyclophosphamide
Cytoxan
76
Cytoxan indication
Cancer
77
Casodex
Bicalutamide
78
Bicalutamide
Casodex
79
Casodex indication
Prostate cancer
80
Casodex MOA
Anti androgen for cancer
81
Evenity
Romosozumab
82
Romosozumab
Evenity
83
Evenity MOA
Sclerostin inhibitor, increases bone formation and slightly decreases bone resorption
84
Evenity common side effects
Joint pain, headache
85
Evenity admin
2 shots sub Q every month
86
Romosozumab boxed warnings
Increased risk of MI, stroke, and cardiovascular death
87
Evenity storage and handling
Refrigerate, may be at room temp for 30 days
88
What supplements needed while on Evenity?
Calcium and vitamin D
89
Myfembree
Relugolix-estradiol-norethindrone
90
Relugolix-estradiol-norethindrone
Myfembree
91
Myfembree MOA and indication
Relugolix: reduces FSH and LH to decrease bleeding from uterine fibroids and pain from endometriosis
Estradiol: reduces bone loss from relugolix
Norethindrone: protects from endometrial cancer from estradiol
Indication: heavy menstrual bleeding in premenopausal women from uterine fibroids and pain with endometriosis
92
Myfembree boxed warning
Clot risk, especially women over 35 who smoke or have uncontrolled HTN
93
Myfembree common side effects
Hot flashes, sweating, abnormal vaginal bleeding, alopecia, decreased sexual interest
94
Anagrelide
Agrylin
95
Agrylin
Anagrelide
96
Anagrelide moa
Reduces platelet count by reduced survival of megakaryocytes
97
Anagrelide indication
Thrombocytopenia secondary to neoplasms to reduce clot risk.
98
Anagrelide common side effects
Heart: chest pain, palpitations, edema
GI: abd pain, NVD
CNS: dizzy, headache, pain, weakness
Respiratory: dyspnea
99
Anagrelide max daily dose
10 mg or 2.5 mg qid
100
Inflectra
Infliximab
101
Why is zymfentra not interchangable with remicade or inflectra?
It is given sub q rather than IV
102
Kesimpta indications and moa
Cd 20 binder and down regulator, leukemia and multiple sclerosis
103
Kesimpta
Ofatumumab
104
Ofatumumab
Kesimpta
105
