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Flashcards in Spleen Deck (28):
1

location of the spleen

Located in the left upper quadrant between the fundus of the stomach, the diaphragm, the splenic flexure of the left colon and the left kidney

2

blood supply for spleen

splenic artery
short gastrics

3

the tail of the pancreas is right near what?

spleen

4

main 2 functions of the spleen

erythrocyte maintenance
immune function

5

causes of hypersplenism

Neoplastic disorders
Hematopoietic disorders
Metabolic or storage disorders
antibodies to platelets or RBCS causing spleen to destroy them

6

diseases associated w/ secondary hypersplenism

Portal HTN
Splenic vein thrombosis
Leukemias/lymphoma
SLE
Gaucher disease
Mononucleosis
Felty syndrome

7

with primary hypersplenism what is indicated

splenectomy

8

bleeding of gastric varcies w/ chronic pancreatitis

splenic vein thrombosis (blood can't get out of the spleen through splenic vein)

9

what is tx for splenic vein thrombosis

splenectomy

10

what autoimmune disease requires a splenecomty (if they have warm antibodies)

acquired hemolytic anemia

11

what meds is acquired hemolytic anemia associated w/

PCN and quinidine

12

what is first line tx for acquire hemolytic anemia?

glucocorticoids

13

Antibodies to platelet antigens
No splenomegaly
Petechiae, ecchymosis, epistaxis and easy bruising

ITP Immune/Idiopathic thrombocytopenia Purpura

14

when do you tx ITP

moderate or severe purpura

15

Tx for ITP

glucocorticoids high dose until platelets go to normal

16

when is splenectomy needed for ITP

people with ITP who fail steroids

17

do you ever get anyone with ITP platelets?

No

18

when do you give platelets in a splenectomy for ITP

clamp across splenic artery

19

common congenital hemolytic anemia
Related to abnormalities in the erythrocyte structure
Affected RBCs have a deficiency in spectrin, an essential component of the cell membrane

hereditary spherocytosis

20

how can someone w/ hereditary spherocytosis present

w/i first 3 decades
splenomegaly common
can present w/ abdominal discomfort and jaundice

21

when should a splenectomy be done with ehreditary spherocytosis

at least age 6
also take the gallbladder out

22

aD trait that results in elliptical erythrocytes increasing rate of destruction of RBC> don't always need a splenectoy

Hereditory Elliptocytosis

23

when do you do a splenectomy with a splenic cyst

if persitss or becomes symptomatic
(can be from hydatid dz)

24

Relatively rare condition that may follow a splenectomy. Infection is with encapsulated organisms (S pneumonia, H influenza, N meningitidis)

Overwhelming postsplenectomy sepsis (OPSS)

25

when shoudl the pneumococcal vaccine be given before an elective splenectomy

2 weeks prior

26

what are other recommended vaccines for someone w/ a splenectomy

pneumococcus
haempholis and meningococcus

27

when do people w/ a splenectomy need abx prophylaxis

invasive medical procedures and dental work

28

what must you look for when doing a splenectomy?

accessory spleen