STEMI, NSTEMI, UA Flashcards

(28 cards)

1
Q

What portion of patients will die from acute MI before reaching hospital - and usually from what?

A

1/5

usually of ventricular fibrillation

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2
Q

What portion of acute MI’s are “silent” - minor pain, attributed to GI tract

A

1/3

Women, elderly, diabetes patients

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3
Q

Result of prolonged myocardial ischemia

- usually result of thrombus formation on atherosclerotic plaque

A

Myocardial Infarction

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4
Q

Most common presenting factor in ACS

A

Nontraumatic chest pain

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5
Q

Other typical chest pain feature of ACS

A

Crushing retrosternal pain / pressure

Heaviness or tightness

Unexplained indigestion / epigastric pain

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6
Q

Describe progression of pain in acute MI

A

Increasingly severe, prolonged (>30min) anterior chest pain at rest

Most often during early morning hours

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7
Q

Be sure to ask specifically about these 5 things in PMH history:

A
  1. Prior coronary bypass graft
  2. Percutaneous coronary intervention (catheterization)
  3. Angina on effort
  4. MI
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8
Q

Vital signs in MI?

A

Bradycardic or Tachycardic

Hypotensive or Hypertensive

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9
Q

Cardiovascular exam in MI?

A

MAY BE NORMAL

  1. Possible JVD
  2. Soft heart sounds
  3. transient murmur of MITRAL REGURGITATION
  4. S4 gllop
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10
Q

What kind of murmur might you hear in someone with acute MI?

A

Mitral Regurgitation

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11
Q

What extra heart sound might you hear in someone w acute MI?

A

S4 gallop

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12
Q

Syndrome which includes pericarditis, fever, leukocytosis, pericardial or pleural effusion that develops 1-2 weeks post-MI

A

Dressler’s syndrome

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13
Q

Fever in MI?

A

YES - low grade fever may develop after 12 hours and last a few days

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14
Q

EKG identification of STEMI

A

ST-segment elevations of >1mm in TWO contiguous leads

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15
Q

Describe the classic progressive changes found in EKG over hours to days in STEMI

A

Peaked T waves > ST-segment elevations > Q waves > T-wave inversion

not present in all cases of MI!!

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16
Q

How would you consider a patient presenting with chest pain and an EKG with ST-segment depression?

A

Unstable Angina or NSTEMI

17
Q

What would cause you to diagnose this patient with ST-segment depression with NSTEMI?

A

If cardiac biomarkers become elevated during evaluation

18
Q

How do EKGs of NSTEMI patients develop?

A

Usually will develop EKG evidence of non-Q-wave MI

25% will develop EKG evidence of Q-wave MI

19
Q

Timing of initial elevation of Troponin T/I?

20
Q

Peak elevation of Troponin T/I

21
Q

When should Troponin T/I be measured?

A

12 hours after onset of pain, then repeated every 8-12 hours

22
Q

Highly sensitive test to quantify extent of infarction?

A

MRI with gladonium contract

23
Q

What all patients with ACS and ongoing discomfort should receive

A

IV Fluids
O2
NTG (0.4mg sublingual every 5 mints x3)
Morphine

Oral Beta Blocker within first 24 hours, unless contraindicated (HF, brady, heart block)

24
Q

When is IV NTG indicated?

A

In first 48 hours for treatment of persistent ischemia, heart failure, or HTN

25
TIMI test for risk (of death) stratification MACES 65 3+
Thrombolysis In Myocardial Infarction 1 point for each of the following - score 3 or more considered high risk: 1. More than one episode rest angina in past 24 hrs 2. Aspirin within past 7 days 3. Known CAD with stenosis 50%+ 4. Elevated cardiac markers 5. ST-segment deviation 6. >65 years 7. 3+ risk factors for CAD
26
GRACE test prediction
6-month risk of death after discharge Global Registry of Acute Coronary Events Age, gender, vital signs, ST-segment changes, historical factors
27
Immediate treatment of STEMi
1. Aspirin and clopidogrel | 2. Coronary angiography and Primary PCI (balloon angioplasty / stent) within 90 mins
28
Immediate treatment of UA/NSTEMI
1. Conservative management appropriate for low-risk patients based on TIMI or GRACE scores - Aspirin and clopidogrel - Anticoagulation 2. Invasive treatment for high risk patients or patients with progressive symptoms / EKG findings - Cardiac catheterization (Angiography, PCI)