Flashcards in Step 2 Deck (2263)
Cause of hemophilia A
Hemophilia B is Factor IX
What is considered precocious puberty?
Girls 8 or younger
Boys 9 or younger
What causes precocious puberty in obese children?
Isolated premature adrenarche
Oily hair/skin, pubic/axillary hair, acne. Generally will not have menarche/thelarche.
Mediated by DHEA-S
Where does the abdomen begin with regard to penetrating injury?
Anything below the nipple is considered to involve abdomen and thorax until proven otherwise.
Indications for ex-lap after penetrating injury
Injury to abdomen or chest below nipples with:
Symptoms of Wilson's Dz
Liver disease (children/adolescents)
Neuropsych disturbances (tremor, rigidity, depression, catatonia)
Diagnosis of Wilson's dz
What is seen on liver biopsy in A1AT deficiency?
Emphysema & early liver failure
PAS-positive and diastase-resistant granules
What drugs cause intersitial nephritis?
Symptoms of drug-induced interstitial nephritis
Acute renal failure
Eosinophilic casts in urine
How long for exclusive breastfeeding?
First 6mo of life
Maternal benefits of breastfeeding
Reduced risk of ovarian and breast cancer
Infant benefits of breastfeeding
Prevention of AOM, NEC, respiratory infx, UTI
Decreased risk of T1DM & childhood cancer
Contraindications to breastfeeding
Untreated maternal TB
Maternal HIV infection
Peripartum maternal varicella infx
Alcohol or drug abuse
Appearance of herpes lesions
Multiple, small, shallow, grouped ulcers
Appearance of H. ducreyi infection
Single or multiple, painful
DEEP ulcers with ragged border
Base may have exudate
Matted LN's can rupture
Which STI ulcers are painful vs. painless
Painful: Herpes, Chancroid (H. ducreyi)
Painless: Syphilis, Chlamydia, Klebsiella granulomatis
Presentation of acute syphilis infection
Single, well-circumscribed painless ulcer
Presentation of Chlamydial ulcers L1-L3 serovars
Small shallow painless ulcers
Immune complex-mediated nephritic syndromes
Diagnosis of post-infectious GN
Oliguria, edema, HTN, coca cola colored urine, recent pharyngitis
Low serum C3
Treatment of IgA nephropathy
ACEi's if proteinuria present
What are the types of nephritic syndrome?
Treatment of Wegener's GN
High dose corticosteroids & cytotoxic agents
Treatment of Goodpasture's syndrome
What is seen in Alport syndrome?
Presents in boys 5-20y
Symptoms of nephritic syndrome
Symptoms of nephrotic syndrome
Proteinuria (>3.5g per day)
What are the causes of nephrotic syndrome?
Minimal change disease