Steroids

Question 1

three categories of steroids

Answer 1

glucocorticosteroids (cortisol)
mineralocorticoids (aldosterone)
sex hormone precursors

Question 2

physiologic effects of steroids

Answer 2

carbohydrate, lipid, and protein metabolism
cardiovascular function
immune function and inflammation

Question 3

short acting glucocorticosteroids

Answer 3

hydrocortisone (cortisol)
cortisone
fludrocortisone (mineralcorticoid)

Question 4

intermediate acting glucocorticosteroids

Answer 4

methylprednisolone
prednisone
triamcinolone

Question 5

long acting glucocorticosteroids

Answer 5

betamethasone

dexamethasone

Question 6

uses for steroids

Answer 6

asthma, sarcoidosis, TB, pericarditis, inflammation, adrenal insuficiency, cushing’s syndrome, immunosupression, rheumatic and collagen disorders, preterm labor, cerebral edema, spinal cord injury, cancer

Question 7

how glucocorticosteroids work

Answer 7

decrease neutrophil migration, decrease prostaglandin and leukotriene synthesis; suppress T lymphocytes, prevent release of inflammatory mediators and histamines

Question 8

Adverse effects of glucocorticosteroids

Answer 8

osteoporosis, peptic ulceration, changes in mood and behavior, edema, HTN, growth suppression in children, cataracts, glaucoma, increase hair growth, weight gain, acne, negative feedback on hypothalamic axis,

Question 9

inhaled steroids

Answer 9

all are (C)
beclomethasone
flunisolide
*fluticasone
triamcinolone
need to rinse mouth after to prevent oral candida; 
used for asthma and COPD

Question 10

intranasal steroid uses

Answer 10

rhinitis, nasal polyps

Question 11

intranasal steroids examples

Answer 11

all are (C)
*beclomethasone
budesonide
flunisolide
*fluticasone
mometasone
triamcinolone

Question 12

ophthalmic steroids uses

Answer 12

post-op inflammation, conjunctivitis, corneal injuries

Question 13

ophthalmic steroid examples

Answer 13

all are (C)
*Dexamethasone
*Prednisolone
Fluoromethalone
Loteprednol
Medrysone
Rimexolone

Question 14

rectal steroids

Answer 14

mostly used for hemorrhoids and ulcerative colitis

hydrocortisone (C)

Question 15

shampoo steroids

Answer 15

primarily used for seborrheic dermatitis

Fluocinolone (C)

Question 16

systemic (PO or parenteral) steroids

Answer 16

betamethasone (C)
budesonide (C)
cortisone acetate (D)
dexamethasone (C)
hydrocortisone (C)
methylprednisolone (C)
prednisolone (B)
triamcinolone (C)

Question 17

topical steroid uses

Answer 17

skin diseases characterized by inflammation, hyper proliferation, and/or immunologic phenomenon, burns, pruritis
ex allergic contact dermatitis, eczema, psoriasis

Question 18

topical steroids ADRs

Answer 18

acne eruption, atrophy of dermis, delayed wound heeling, secondary infection, contact dermatitis

Question 19

low potency topical steroids

Answer 19

alclometasone dipropionate
desonide
fluocinolone acetonide
hydrocortisone
hydrocortisone acetate

Question 20

intermediate potency topical steroids

Answer 20

betamethasone dipropionate 0.05% lotion
betamethasone valerate 0.1% cream
clocortolone pivalate
desoximetasone cream
fluocinolone acetonide
flurandrenolide
fluticasone propionate
hydrocortisone butyrate
hydrocortisone valerate
mometasone furoate
prednicarbate
triamcinolone acetonide 0.025%, 0.1%

Question 21

hi potency topical steroids

Answer 21

amcinonide
betamethasone diprop 0.05% cream
betamethasone valerate
desoximetasone  0.05% gel, 0.25% cream, oint
fluocinonide
halcinonide
triamcinolone acetonide 0.5%

Question 22

very hi potency steroids

Answer 22

betamethasone diprop 0.05% oint
clobetasol propionnate
diflorasone diacetate
halobetasol propionate