Steroids and Adrenal Gland Flashcards Preview

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Flashcards in Steroids and Adrenal Gland Deck (5)
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1

What is the effects of cortisol?

antagonist to insulin -> causes gluconeogenesis, fat and protein breakdown (strongest antagonist when compared with glucagon and somatostatin)
lowers immune reactivity, raises BP, inhibits bone synthesis

2

What are adverse effects of therapeutic steroid use?

hypertension, type II diabetes, osteoporosis, increased infection risk

3

What are examples of therapeutic steroids?

hydrocortisone (cortisol equivalent = 1)
prednisalone (4)
triamcinolone (5)
dexamethasone (25)
betamethasone (30)

4

What are the effects of therapeutic steroids?

enhanced glucocorticoid effect
enhanced mineralocorticoid effect (salt and water retention, hypertension)
ALSO cause suppression of adrenal function

5

What hormones are produced by the adrenal glands? Where are these produced in the adrenal glands?

aldosterone -> zona glomerulosa
cortisol -> zona fasicularis
adrenal androgens -> zona reticularis
adrenaline -> medulla