Flashcards in Steroids and Adrenal Gland Deck (5)
What is the effects of cortisol?
antagonist to insulin -> causes gluconeogenesis, fat and protein breakdown (strongest antagonist when compared with glucagon and somatostatin)
lowers immune reactivity, raises BP, inhibits bone synthesis
What are adverse effects of therapeutic steroid use?
hypertension, type II diabetes, osteoporosis, increased infection risk
What are examples of therapeutic steroids?
hydrocortisone (cortisol equivalent = 1)
What are the effects of therapeutic steroids?
enhanced glucocorticoid effect
enhanced mineralocorticoid effect (salt and water retention, hypertension)
ALSO cause suppression of adrenal function