Stroke Flashcards

1
Q

Stroke is….

A

Sudden onset

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2
Q

What are the most likely causes of cerebral ischemia due to perfusion failure?

A

Severe stenosis of carotid and basilar artery

Microstenosis of small deep arteries

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3
Q

Describe the presentation of a ‘watershed’ infarction

A

The effects of perfusion failure are felt first at the distal territories before proximal ones

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4
Q

What are the most likely causes of embolism of brain of cardiac or aortic origin?

A

AF

Recent acute MI

Subacute bacterial endocarditis

Valvular disorders

Cardiac tumors

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5
Q

What are the most likely causes of intracerebral haemorrhage?

A

HTN

Warfarin use

Head trauma

Ruptured cerebral aneurysm

Arteriovenous malformation

Cocaine or meth use

Bleeding tumors

Bleeding disorders (haemophilia)

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6
Q

A patient presents with sudden onset leg weakness. Which vessel is most likely compromised in this patient?

A

ACA

Homunculus

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7
Q

What are the 4 categories in the Oxford/Bamford stroke classification?

A

TACS

PACS

LACS

POCS

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8
Q

What does TACS stand for?

A

Total anterior circulation stroke

Larger MCA or ACA stroke

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9
Q

What does PACS stand for?

A

Partial anterior circulation stroke

Cortical MCA or ACA stroke

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10
Q

What does LACS stand for?

A

Lacunar syndrome

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11
Q

What does POCS stand for?

A

Posterior circulation stroke

Brainstem/cerebellar arteries

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12
Q

What 3 symptoms MUST a patient present with to consider a TACS?

A

Unilateral weakness
- +/- sensory changes

Homonymous hemianopia

Higher cortical dysfunction

  • speech
  • visuospatial problems
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13
Q

Name 3 symptoms a patient COULD present with in a PACS stroke

(Need 2 out of 3 to be PACS stroke)

A

Unilateral weakness
- +/- sensory changes

Homonymous hemianopia

Higher cortical dysfunction

  • speech
  • visuospatial problems
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14
Q

Name 3 symptoms a patient COULD present with in a LACS stroke

(Need 1 of the following)

A

Unilateral weakness
- +/- sensory changes

Pure sensory or pure motor

Ataxic hemiparesis

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15
Q

Name 4 symptoms a patient COULD present with in POCS stroke

Need 1 of the following

A

Bilateral motor or sensory deficit

Cerebellar/brainstem signs

Isolated homonymous hemianopia

Cranial nerve palsy and contralateral motor/sensory deficit

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16
Q

What are cerebellar signs?

A

Dysdiadokinesia & Dysmetria

Ataxia

Nystagmus

Intention tremor

Slurred speech

Hypotonia

17
Q

How would cerebellar symptoms present?

A

D - past pointing, inability to perform and sustain a series of rapidly alternating muscle movements (typically flipping one hand rapidly in the palm of the other

A- gross incoordination of muscle movements

N- nystagmus

I - low, coarse, low frequency tremor that gets worse towards the termination of the action

S - slurred speech

H- low muscle tone

18
Q

Describe a watershed infarct

A

Result from systemic hypotension causing infarcts in areas of overlap and supply

19
Q

Which arteries are most likely to have been affected in watershed infarcts?

A

ACA-MCA infarct caused by occlusion of carotid artery

20
Q

How will a patient present with a watershed infarct?

A

Man in a barrel

-loss of trunk sensation/motor function and aphasia

21
Q

How would a patient with an MCA-PCA present?

A

Affects visual processing

22
Q

Which nuclei/tracts are damaged in lateral medullary syndrome?

A

Vestibular nuclei

Inferior cerebellar peduncle

Central tegmental tract

Lateral spinothalamic tract

Spinal trigeminal nucleus and tract

Nucleus ambiguous

Descending sympathetic fibres

23
Q

What symptoms may a patient present with in lateral medullary syndrome?

A

Vestibular: vomiting vertigo, nystagmus

Ipsilateral cerebellar signs: ataxia, dysmetria, dysdiadochokinesia

Palatal myoclonus

Contralateral pain and temperature loss from body

Ipsilateral pain and temperature loss from face

Ipsilateral dysphagia, hoarseness, absent gag reflex (ambiguous)

Ipsilateral Horner’s syndrome

24
Q

Name some general symptoms of stroke

A

Weakness/Paralysis or numbness on contralateral side

Vertigo/dizziness

Headache

Visual loss/blurred vision

Faintness

Confusion

Speech problems

Difficulty swallowing

Cognitive problems

Memory problems

Consciousness alterations

25
What drug is given as a clot buster in A+E?
Alteplase
26
What tool is used to assess someone's likelihood of a stroke after a TIA?
ABCD2
27
Describe the acute management of stroke
Imaging Ischaemic/haemorrhagic Aspirin Pyrexia, glucose TEDS NBM/SALT Thrombolysis/other agents BP
28
How soon should alteplase be given?
Within 4.5 hours The quicker the better
29
What complications need to be considered after acute management of stroke?
Swallow DVT prophylaxis Pressure areas Continence Speech Infections (chest, UTI, skin) Contractures Pain Depression
30
What needs to be considered in secondary prevention of stroke?
IHD DM ?AF - anticoagulation Anterior circulation Smoking cessation Aspirin/clopidogrel, statin, BP control