Study Group Qs Flashcards

1
Q

What is the r value for perfect negative correlation?

A. R = 1
B. R = 0
C. R = -1
D. R = -0.5

A

What is the r value for perfect negative correlation?

A. R = 1
B. R = 0
C. R = -1
D. R = -0.5

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2
Q

What happens to the confidence interval as sample size increases?

A. Doubles
B. Stays the same
C. Gets bigger
D. Gets narrower

A

What happens to the confidence interval as sample size increases?

A. Doubles
B. Stays the same
C. Gets bigger
D. Gets narrower

If the sample size increases, the 95% confidence range stays the same;
however the 95% confidence interval gets narrow since the standard error decreases if the sample size is larger

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3
Q

What study type should be used if you wanted to investigate if a rare exposure is associated with a disease?

A. Cohort study
B. Case control study
C. Clinical trial
D. Cross-sectional survey

A

What study type should be used if you wanted to investigate if a rare exposure is associated with a disease?

A. Cohort study
B. Case control study
C. Clinical trial
D. Cross-sectional survey

If an exposure is rare there may be too few people exposed in a case-control study to be able to draw conclusions

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4
Q

What study types is this graph often used in?

A. Cohort study
B. Case control study
C. Clinical trial
D. Cross-sectional survey

A

What study types is this graph often used in?

A. Cohort study

Kaplan-Meier curves
Plot proportion of people surviving over time
Compared using a log rank test
Used in cohort studies and randomized trials.

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5
Q

Where is aldosterone secreted from?

A. Zona reticularis
B. Zona fasciculata
C. Zona Glomerulosa
D. Cortex

A

Where is aldosterone secreted from?

A. Zona reticularis
B. Zona fasciculata
Zona Glomerulosa
D. Cortex

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6
Q

Which one of these would decrease satiety?
A. Insulin
B. Ghrelin
C. Leptin
D. Glucagon-like peptide

A

Which one of these would decrease satiety?
A. Insulin
B. Ghrelin
C. Leptin
D. Glucagon-like peptide

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7
Q

What acid-base disturbance is common in acute COPD?
A. Metabolic alkalosis
B. Metabolic acidosis
C. Respiratory alkalosis
D. Respiratory acidosis

A

D. Respiratory acidosis

Respiratory acidosis with no compensation.
Lost sensitivity to CO2, only thing keeping patient breathing is that they are hypoxic 🡪 lost respiratory drive

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8
Q

Which of these causes hyperkaleamia?
A. Beta blockers
B. Diarrhoea
C. Alcoholism
D. Diuretics

A

Which of these causes hyperkaleamia?
A. Beta blockers
B. Diarrhoea
C. Alcoholism
D. Diuretics

RAAS inhibition

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9
Q

What is the rate determining enzyme in glycolysis?
A. Fructose-1,6-biphosphate
B. Glycogen synthase
C. Glycogen phosphorylase
D. Phosphofructokinase-1

A

What is the rate determining enzyme in glycolysis?
A. Fructose-1,6-biphosphate
B. Glycogen synthase
C. Glycogen phosphorylase
D. Phosphofructokinase1

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10
Q

There are different types of analysis used within statistics. What is a t-test used to compare?

A – Medians of a continuous variable between 2 groups
B – Proportions of a binary variable between 2 groups
C – Proportions of binary variable within one group, measured at 2 time points
D – Standard deviations of a continuous variable between 2 groups
E – Means of a continuous variable between 2 groups

A

There are different types of analysis used within statistics. What is a t-test used to compare?

A – Medians of a continuous variable between 2 groups
B – Proportions of a binary variable between 2 groups
C – Proportions of binary variable within one group, measured at 2 time points
D – Standard deviations of a continuous variable between 2 groups
E – Means of a continuous variable between 2 groups

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11
Q

Regurgitation through the tricuspid valve would lead to volume overload of which heart chamber?

A – R.V.
B – R.A.
C – L.V.
D – L.A.

A

Regurgitation through the tricuspid valve would lead to volume overload of which heart chamber?

A – R.V.
B – R.A.
C – L.V.
D – L.A.

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12
Q

Which type of brain herniation causes ipsilateral mydriasis (pupil dilation)?

A – Central (transtentorial)
B – Cingulate (Subfalcine)
C – Transcalvarial
D – Uncal
E – Upward cerebellar (transtentorial)

A

Which type of brain herniation causes ipsilateral mydriasis (pupil dilation)?

A – Central (transtentorial)
B – Cingulate (Subfalcine)
C – Transcalvarial
D – Uncal
E – Upward cerebellar (transtentorial)

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13
Q

A 61 year old woman presents to the emergency department with diarrhoea and vomiting. She has recently been started on furosemide by her GP for hypertension. What has happened?

A

Hypokalaemia
Inverted QRS (Possible block)
T-wave flattening
Possibly due to new loop diuretic (furosemide)

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14
Q

What type of bleed is diagnosed using lumbar puncture (as well as CT)? What colour is the CSF when it is examined?

A – Epidural haematoma (Colourless)
B – Extradural haematoma (Yellow)
C – Subarachnoid haematoma (Yellow)
D – Subdural haematoma (Colourless)
E – Arteriovenous malformations (Colourless)

A

What type of bleed is diagnosed using lumbar puncture (as well as CT)? What colour is the CSF when it is examined?

A – Epidural haematoma (Colourless)
B – Extradural haematoma (Yellow)
C – Subarachnoid haematoma (Yellow)
D – Subdural haematoma (Colourless)
E – Arteriovenous malformations (Colourless)

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15
Q

Which of the following signs might be seen in shaken baby syndrome?

A – Anencephalopathy
B – Subarachnoid haemorrhage
C – Subdural haemorrhage
D – Epidural haemorrhage
E – Arteriovenosus malformations

A

Which of the following signs might be seen in shaken baby syndrome?

A – Anencephalopathy
B – Subarachnoid haemorrhage
C – Subdural haemorrhage
D – Epidural haemorrhage
E – Arteriovenosus malformations

Encephalopathy, Subdural haemorrhage and Retinal haemorrhage

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16
Q

Which of the following can be given/performed to temporarily stop contractions during pregnancy?

A – Amniofusion
B – Dexamethasone
C – Oxytocin
D – Azithromycin
E - Tocolysis

A

Which of the following can be given/performed to temporarily stop contractions during pregnancy?

A – Amniofusion
B – Dexamethasone
C – Oxytocin
D – Azithromycin
E - Tocolysis

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17
Q

Where is the active form of Vitamin D synthesised?

A – Liver
B – Lungs
C – Kidneys
D– Skeletal muscle
E – Smooth muscle

A

Where is the active form of Vitamin D synthesised?

A – Liver
B – Lungs
C – Kidneys
D– Skeletal muscle
E – Smooth muscle

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18
Q

As it exits the axilla the radial nerve lies on which of the following muscles?
A – Teres Minor
B – Teres Major
C – Pectoralis Minor
D – Pectoralis Major
E – Biceps brachii

A

As it exits the axilla the radial nerve lies on which of the following muscles?
A – Teres Minor
B – Teres Major
C – Pectoralis Minor
D – Pectoralis Major
E – Biceps brachii

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19
Q

Which cardiac abnormality is most common in a baby with Patau’s syndrome?
A – Tetralogy of Fallot
B – Coarction of the aorta
C – ASD
D – VSD
E - PDA

A

Which cardiac abnormality is most common in a baby with Patau’s syndrome?
A – Tetralogy of Fallot
B – Coarction of the aorta
C – ASD
D – VSD
E - PDA

Patau’s syndrome – Chromosome 13
VSD most commonly associated
-> Can lead to Eisenmenger syndrome

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20
Q

Name the least abundant isotype in blood serum
IgA
IgM
IgG
IgE
IgD

A

Name the least abundant isotype in blood serum
IgA
IgM
IgG
IgE
IgD

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21
Q

Which cell type in the nervous system provides the inner lining of the ventricles?
Oligodendrocytes
Astrocytes
Microglia
Ependymal cells
Schwann cells

A

Which cell type in the nervous system provides the inner lining of the ventricles?
Oligodendrocytes
Astrocytes
Microglia
Ependymal cells
Schwann cells

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22
Q

Which valvular disorder is most commonly seen in acute rheumatic fever?
Mitral stenosis
Aortic stenosis
Pulmonary stenosis
Mitral regurgitation
Aortic regurgitation

A

Which valvular disorder is most commonly seen in acute rheumatic fever?
Mitral stenosis
Aortic stenosis
Pulmonary stenosis
Mitral regurgitation
Aortic regurgitation

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23
Q

What is inspiratory capacity?

Max. volume of air that can be inspired at the end of a normal tidal inspiration
Equals residual volume + vital capacity
Equals tidal volume + inspiratory reserve volume
350ml in females, 500ml in males
3500ml in females, 4500ml in males

A

What is inspiratory capacity?
Max. volume of air that can be inspired at the end of a normal tidal inspiration
Equals residual volume + vital capacity
Equals tidal volume + inspiratory reserve volume
350ml in females, 500ml in males
3500ml in females, 4500ml in males

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24
Q

What are the cells affects in multiple sclerosis?
A. Schwann cells
B. Oligodendrocytes
C. Microglia
D. Astrocytes

A

What are the cells affects in multiple sclerosis?
A. Schwann cells
B. Oligodendrocytes
C. Microglia
D. Astrocytes

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25
Which one of these is the cell type of acoustic neuromas? A. Schwann cells B. Oligodendrocytes C. Microglia D. Astrocytes
Which one of these is the cell type of acoustic neuromas? **A. Schwann cells** B. Oligodendrocytes C. Microglia D. Astrocytes
26
A 55-year-old men presents with fever, shortness of breath and pleuritic chest pain. What is shown in his CXR? Right sided Pleural effusion Right middle lobe consolidation Right lower lobe consolidation Asbestosis R.sided collapsed lung
A 55-year-old men presents with fever, shortness of breath and pleuritic chest pain. What is shown in his CXR? Right sided Pleural effusion **Right middle lobe consolidation** Right lower lobe consolidation Asbestosis R.sided collapsed lung
27
A 62-year-old man is investigated for increasing shortness-of-breath. Pulmonary fibrosis COPD Cancer Heart failure
A 62-year-old man is investigated for increasing shortness-of-breath. Pulmonary fibrosis **COPD** Cancer Heart failure
28
A 22 year old boy present to A&E, after been stabbed in the chest, with acute shortness of breath and hypotension. L.sided tension pneumothorax R.sided consolidation R.sided tension pneumothorax Normal lung
A 22 year old boy present to A&E, after been stabbed in the chest, with acute shortness of breath and hypotension. **L.sided tension pneumothorax** R.sided consolidation R.sided tension pneumothorax Normal lung
29
What is the life threatening abnormality? A - Tension pneumothorax B - Pneumoperitoneum C - Pneumobilia D - Pulmonary oedema
What is the life threatening abnormality? A - Tension pneumothorax B - **Pneumoperitoneum** C - Pneumobilia D - Pulmonary oedema
30
A 55 year old male presents to his GP with a progressive exertional dyspnoea and a persistent dry cough. X-ray was taken. Pleural effusion Consolidation Pulmonary fibrosis Cardiomegaly
A 55 year old male presents to his GP with a progressive exertional dyspnoea and a persistent dry cough. X-ray was taken. Pleural effusion Consolidation **Pulmonary fibrosis** Cardiomegaly
31
A patient has a 10-29% risk of CAD: What investigation is most appropriate? Angiography Full blood count c. Functional imaging d. CT calcium scoring e. Rule out non-cardiac causes of chest pain
A patient has a 10-29% risk of CAD: What investigation is most appropriate? Angiography If 61-90% Full blood count c. Functional imaging **d. CT calcium scoring** measurement of calcium present in coronary arteries: assess degree of coronary artery disease e. Rule out non-cardiac causes of chest pain
32
What type of shock are burns? A. obstructive B. Hypovolaemic C. cardiogenic D. neurogenic
What type of shock are burns? A. obstructive **B. Hypovolaemic** C. cardiogenic D. neurogenic
33
Patient presents with diurnal wheeze, and cough on exercise. His FEV1:FVC is 50% of predicted based on his age. What do you interpret from this? Normal Mild Moderate Severe
Patient presents with diurnal wheeze, and cough on exercise. His FEV1:FVC is 50% of predicted based on his age. What do you interpret from this? Normal Mild **Moderate** Severe
34
What is the MOA of rifampicin a. Cytochrome P450 inhibitor b. Bacteriostatic c. DNA synthesis inhibitor d. RNA polymerase inhibitor
What is the MOA of rifampicin a. Cytochrome P450 inhibitor b. Bacteriostatic c. DNA synthesis inhibitor **d. RNA polymerase inhibitor**
35
Which cranial nerve is most likely to be affected first by a cavernous ICA aneurysm? a) Ophthalmic nerve V1 b) Abducens nerve c) Occulomotor nerve d) Trochlear nerve e) Maxillary nerve V2
Which cranial nerve is most likely to be affected first by a cavernous ICA aneurysm? a) Ophthalmic nerve V1 **b) Abducens nerve** c) Occulomotor nerve d) Trochlear nerve e) Maxillary nerve V2
36
Where does the Mandibular nerve exit the skull? a) Foramen rotundum b) SOB c) Optic canal d) Foramen ovale
Where does the Mandibular nerve exit the skull? a) Foramen rotundum b) SOB c) Optic canal **d) Foramen ovale**
37
Where does the Ophthalmic nerve exit the skull? a) Foramen rotundum b) SOB c) Optic canal d) Foramen ovale
Where does the Ophthalmic nerve exit the skull? a) Foramen rotundum **b) SOB** c) Optic canal d) Foramen ovale
38
Where does the trochlear nerve exit the skull? a) Foramen rotundum b) SOB c) Optic canal d) Foramen ovale
Where does the trochlear nerve exit the skull? a) Foramen rotundum **b) SOB** c) Optic canal d) Foramen ovale
39
Where would a gall stone be lodged that causes pancreatitis? A) Common bile duct B) Cystic duct C) Common hepatic duct D) Ampulla of Vater
Where would a gall stone be lodged that causes pancreatitis? A) Common bile duct B) Cystic duct C) Common hepatic duct **D) Ampulla of Vater**
40
What structure is the arrow pointing to? A) Adenocarcinoma B) Central vein C) Bile duct D) Hepatic artery
What structure is the arrow pointing to? A) Adenocarcinoma B) Central vein C) Bile duct **D) Hepatic artery**
41
Which of the following is a symptom of late Congenital syphilis? A – Rash B – Rhinorrhoea C – Saber shins D – Osteochondritis E - Lymphadenopathy
Which of the following is a symptom of late Congenital syphilis? A – Rash B – Rhinorrhoea **C – Saber shins** D – Osteochondritis E - Lymphadenopathy
42
A foetal ultrasound identifies the following, what is the likely diagnosis? A – Gastroschisis B – Myelomengocele C – Omphalocele D – Placental abruption E - Spina bifida occulta
A foetal ultrasound identifies the following, what is the likely diagnosis? A – Gastroschisis B – Myelomengocele **C – Omphalocele** D – Placental abruption E - Spina bifida occulta Gastroschisis would be everywhere
43
Identify A: A – Membranous urethra B – Ischiocavernosus C – Transverse perineal muscles D – Bulbospongiosum E - Puborectalis
A – Membranous urethra B – Ischiocavernosus C – Transverse perineal muscles **D – Bulbospongiosum** E - Puborectalis
44
In which part of the reproductive system do sperm become motile? A – Seminiferous tubules B – Membranous urethra C – Spongy urethra D – Epididymis E - Prostate
In which part of the reproductive system do sperm become motile? A – Seminiferous tubules B – Membranous urethra C – Spongy urethra **D – Epididymis** E - Prostate
45
Which of the following drugs should not be consumed with foods like mature cheese, pickles and wine? A – Escitalopram B – Imipramine C – Phenelzine D – Reboxetine E – Trazodone
Which of the following drugs should not be consumed with foods like mature cheese, pickles and wine? A – Escitalopram B – Imipramine **C – Phenelzine** D – Reboxetine E – Trazodone Phenelzine = MAOI (irreversible) and interacts with tyramine containing foods. Restrictions continue at least 2 weeks after discontinuing it.
46
Which of these lesions is most commonly associated with Barrett’s oesophagus? A – Squamous cell carcinoma B – Gastro intestinal stromal tumour C – Carcinoid tumours D – Leiomyosarcoma E - Adenocarcinoma
Which of these lesions is most commonly associated with Barrett’s oesophagus? A – Squamous cell carcinoma B – Gastro intestinal stromal tumour C – Carcinoid tumours D – Leiomyosarcoma **E - Adenocarcinoma**
47
Which of the following is responsible for vasoconstriction? A – Parasympathetic nervous input B – Endothelin C – Nitric oxide D – Prostacyclin E - Erythropoetin
Which of the following is responsible for vasoconstriction? A – Parasympathetic nervous input **B – Endothelin** C – Nitric oxide D – Prostacyclin E - Erythropoetin
48
A researcher is interested in investigating a recent outbreak of Listeria monocytogenes. Which of the following best describes the design of this study? A – Case-control study B – Randomised control trial C – Cohort D – Cross-sectional study E – Meta-analysis
A researcher is interested in investigating a recent outbreak of Listeria monocytogenes. Which of the following best describes the design of this study? **A – Case-control study** B – Randomised control trial C – Cohort D – Cross-sectional study E – Meta-analysis
49
A – Hepatic artery proper B – Gastroduodenal artery C – Splenic artery D – Left gastric artery E – Right gastric artery
A – Hepatic artery proper
50
The presence of what in the CSF might indicate Multiple Sclerosis? A – Venous blood B – Arterial blood C – Oligoclonal bands D – Grey matter E – White matter
The presence of what in the CSF might indicate Multiple Sclerosis? A – Venous blood B – Arterial blood **C – Oligoclonal bands** D – Grey matter E – White matter
51
Where is GnRH released from? A – Anterior pituitary B – Posterior pituitary C – Zona fasciculata D – Hypothalamus E – Zona glomerulosa
Where is GnRH released from? A – Anterior pituitary B – Posterior pituitary C – Zona fasciculata D – **Hypothalamus** E – Zona glomerulosa
52
Which of the following is another cause of Hypothyroidism? A – Excess iodine B – Aminodarone C – Cabbage D – Hamburger thyroxicosis E - Thyroditis
Which of the following is another cause of Hypothyroidism? A – Excess iodine B – Aminodarone C – **Cabbage** D – Hamburger thyroxicosis E - Thyroditis
53
Subfalcine
54
Insula
55
Truncal ataxia
56
Obturator
57
What are the boundaries of the femoral triangle? [3]
58
B - thalamus
59
C
60
What nerve is most at risk from an anterior shoulder dislocation? a) Radial b) Median c) Axillary d) Long thoracic e) Musculocutaneous
What nerve is most at risk from an anterior shoulder dislocation? a) Radial b) Median **c) Axillary** d) Long thoracic e) Musculocutaneous
61
What type of collagen is found in the bone? [1]
Type 1
62
Omphalocele
63
IMA
64
Hydrocephalus
65
Nav 1.7
66
Graphesthesia – recognising movements on skin