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Flashcards in Sulfonomides Deck (2)
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Trimethoprim-sulfamethoxazole (Bactrium, Septra)

Therapeutic classification- antibacterial

Pharmacologic class-folic acid inhibitor, sulfonamide

Pregnancy category C

Contraindications-
Hypersensitivity to sulfites, sulfonamides, or chemically related agents
Folate deficiency anemia
Severe renal impairment
Hyperkalemia

Adverse effects-
Nausea and vomiting
Skin rash
Pruritis
Fever
Photosensitivity

Patient family teaching-
Immediately report a rash, fever, purpura, sore throat, or jaundice
Drink 2 to 3 L (1 L is approximately equal to 1 quart) of fluids daily
Immediately reports severe or persistent diarrhea with fever; no OTC remedies
Report no improvement after a few days of therapy
Do not breast-feed

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Nitrofurantoin (Furdantin) and
Nitrofurantoin Macrocrystals (Macrobid, Macrodantin)

Therapeutic class- antibacterial

Pharmacologic class – urinary tract antiseptic

Pregnancy category B

Contraindications –
Renal impairment
Pregnancy or neonate <1 month old
Diffuse interstitial pneumonitis or pulmonary fibrosis

Adverse effects –
Hypersensitivity reactions
Anorexia
Headache
Rash
Nausea
Vomiting

Patient family teaching –
*Report difficulty breathing, changes in urination (other than brown discoloration), nausea, vomiting, diarrhea, rash, chest pain, cough, fever, vision changes, unusual bleeding, yellowing of skin, or light colored stools
*Urine may have harmless brown color
*Consult provider on fluid intake
*immediately report severe or persistent diarrhea with fever; no OTC treatments
*Report if no improvement after a few days
*Do not breast-feed