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Flashcards in Test 1 Deck (229)
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1

Which gland can be enlarged during bilateral renal agenesis?

adrenal

2

Is adrenal hypoplasia more common as a unilateral or bilateral defect?

unilateral

3

What other two organs can cysts manifest during ADPKD? Interfere with function?

liver and spleen

no

4

Why can ADPKD cause hemorrhage? What type of bleed?

berry aneurysm

subarachnoid

5

What gene is affected during ARPKD?

PKHD1

6

Is ARPKD a smooth or rough appearing kidney?

smooth

7

What disease process is ARPKD associated with?

congenital hepatic fibrosis

8

What type of immunofluorescence pattern would Goodpastures have?

linear

9

Which immunoglobulins are stained for with immune fluorescence?

G/A/M

10

Which complement proteins are stained for with immune fluorescence?

C3 and C1q

11

Which TWO light chains are stained for using immunofluorescence?

kappa and lambda light chains

12

What type of casts are seen during nephrotic syndrome?

fatty

13

What type of casts are seen during nephritic syndrome?

RBC

14

What structure 'breaks' during nephritic syndrome?

capillary loops

15

Is FSGS nephritic or nephrotic?

nephrotic

16

What is another name for Lipoid Nephrosis?

MCD

17

What is the cardinal feature of FSGS?

glomerular scarring

18

What is the most common virus to cause FSGS?

HIV

19

What is the most common drug to cause FSGS?

heroin

20

Familial FSGS can be caused by defective genes for what structure?

Podocytes

21

What does FSGS show on light microscopy ?

segmental sclerosis

22

Which two proteins may be seen during IF regarding FSGS? Where?

IgM and C3

areas of sclerosis

23

What does membranous Glomerulopathy show on LM?

'spikes'

24

What does membranous Glomerulopathy show on IF?

granular IgG and C3

25

Where are the EM deposits seen during Membranous Glomerulopathy?

subepithelial

26

Is MPGN nephritic or nephrotic?

both

27

Does MPGN respond to seroids?

no

28

Where are the deposits seen during Type One MPGN?

subendothelial

29

Where are the deposits seen during Type Two MPGN?

intramembranous

30

What cell proliferates during MPGN?

mesangial