Flashcards in Test 1 Deck (229)
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1
Which gland can be enlarged during bilateral renal agenesis?
adrenal
2
Is adrenal hypoplasia more common as a unilateral or bilateral defect?
unilateral
3
What other two organs can cysts manifest during ADPKD? Interfere with function?
liver and spleen
no
4
Why can ADPKD cause hemorrhage? What type of bleed?
berry aneurysm
subarachnoid
5
What gene is affected during ARPKD?
PKHD1
6
Is ARPKD a smooth or rough appearing kidney?
smooth
7
What disease process is ARPKD associated with?
congenital hepatic fibrosis
8
What type of immunofluorescence pattern would Goodpastures have?
linear
9
Which immunoglobulins are stained for with immune fluorescence?
G/A/M
10
Which complement proteins are stained for with immune fluorescence?
C3 and C1q
11
Which TWO light chains are stained for using immunofluorescence?
kappa and lambda light chains
12
What type of casts are seen during nephrotic syndrome?
fatty
13
What type of casts are seen during nephritic syndrome?
RBC
14
What structure 'breaks' during nephritic syndrome?
capillary loops
15
Is FSGS nephritic or nephrotic?
nephrotic
16
What is another name for Lipoid Nephrosis?
MCD
17
What is the cardinal feature of FSGS?
glomerular scarring
18
What is the most common virus to cause FSGS?
HIV
19
What is the most common drug to cause FSGS?
heroin
20
Familial FSGS can be caused by defective genes for what structure?
Podocytes
21
What does FSGS show on light microscopy ?
segmental sclerosis
22
Which two proteins may be seen during IF regarding FSGS? Where?
IgM and C3
areas of sclerosis
23
What does membranous Glomerulopathy show on LM?
'spikes'
24
What does membranous Glomerulopathy show on IF?
granular IgG and C3
25
Where are the EM deposits seen during Membranous Glomerulopathy?
subepithelial
26
Is MPGN nephritic or nephrotic?
both
27
Does MPGN respond to seroids?
no
28
Where are the deposits seen during Type One MPGN?
subendothelial
29
Where are the deposits seen during Type Two MPGN?
intramembranous
30
