Test 1 Flashcards
(229 cards)
Which gland can be enlarged during bilateral renal agenesis?
adrenal
Is adrenal hypoplasia more common as a unilateral or bilateral defect?
unilateral
What other two organs can cysts manifest during ADPKD? Interfere with function?
liver and spleen
no
Why can ADPKD cause hemorrhage? What type of bleed?
berry aneurysm
subarachnoid
What gene is affected during ARPKD?
PKHD1
Is ARPKD a smooth or rough appearing kidney?
smooth
What disease process is ARPKD associated with?
congenital hepatic fibrosis
What type of immunofluorescence pattern would Goodpastures have?
linear
Which immunoglobulins are stained for with immune fluorescence?
G/A/M
Which complement proteins are stained for with immune fluorescence?
C3 and C1q
Which TWO light chains are stained for using immunofluorescence?
kappa and lambda light chains
What type of casts are seen during nephrotic syndrome?
fatty
What type of casts are seen during nephritic syndrome?
RBC
What structure ‘breaks’ during nephritic syndrome?
capillary loops
Is FSGS nephritic or nephrotic?
nephrotic
What is another name for Lipoid Nephrosis?
MCD
What is the cardinal feature of FSGS?
glomerular scarring
What is the most common virus to cause FSGS?
HIV
What is the most common drug to cause FSGS?
heroin
Familial FSGS can be caused by defective genes for what structure?
Podocytes
What does FSGS show on light microscopy ?
segmental sclerosis
Which two proteins may be seen during IF regarding FSGS? Where?
IgM and C3
areas of sclerosis
What does membranous Glomerulopathy show on LM?
‘spikes’
What does membranous Glomerulopathy show on IF?
granular IgG and C3