Test 1 Immunoglobulins Flashcards
(41 cards)
1
Q
Gamma heavy chain
A
IgG
2
Q
Mu heavy chain
A
IgM
3
Q
Alpha heavy chain
A
IgA
4
Q
Epsilon heavy chain
A
IgE
5
Q
Delta heavy chain
A
IgD
6
Q
180,000 D molecular weight
A
IgG
7
Q
900 kD molecular weight
A
IgM
8
Q
400 kD molecular weight
A
IgA
9
Q
180 molecular weight
A
IgE and IgD
10
Q
IgG shape
A
monomer
11
Q
IgM shape
A
pentamer
12
Q
IgA shape
A
dimeric; monomer/polymer (2IgA molecules joined by J chain)
13
Q
IgE shape
A
monomer (in serum)
14
Q
IgD shape
A
monomer
15
Q
Most clinically significant
A
IgG
16
Q
Destroys antigen coated transfused red cells
A
IgG
17
Q
Macrophage Fc receptors
A
IgG
18
Q
Reaction temp at 37 degrees
A
IgG
19
Q
Activates complement
A
IgG and IgM
20
Q
Crosses the placenta
A
IgG
21
Q
Hemlytic disease of the newborn
A
IgG
22
Q
Naturally occuring
A
IgM
23
Q
Interfers with detection of IgG anitbodies
A
IgM
24
Q
Primary immune response
A
IgM
25
Subclasses IgM1, IgM2
IgM
26
First immunoglobulin produced in fetus
IgM
27
Antibodies in ABO blood system
IgM
28
Confined to blood stream
IgM
29
Antibody-antigen agglutination
IgM
30
May enhance autoimmune RBC hemolysis
IgA
31
Sound in secretions
IgA
32
No bacteriocidal effects
IgA
33
Localizes infectious agents
IgA
34
Subclasses IgA1, IgA2
IgA
35
Triggers cellular release of histamine
IgE
36
Use antihistamines during transfusion to prevent allergic react/ anaphylaxis
IgE
37
Shortests half life, highest catabolic rate, lowest synthesis rate
IgE
38
Bound by Fc portion to basophils and mast cells
IgE
39
Increased vascular permeability
IgE
40
May relate to maturation/ differentiation of B cells
IgD
41
No blood group antibodies
IgD
