Test 3 Lecture Flashcards
(86 cards)
Germ-line cells
Sex cells, produce sexually
Somatic cells
All other cells produce asexually
Mitosis
Ordinary somatic cell division- makes 2 cells
Diploid
2n 46 chromosomes
Meiosis
germlins cell division results in 4 non-identical
Haploid cells
n chromosome- 23
The First Stage of the Cell Cycle
1) Cell growth
Increase in body size during growth
The Second Stage of the Cell Cycle
2) Cell repair
The replacement of dead or worn out cells
The Third Stage of the Cell Cycle
3) Cellular reproduction
Asexual reproduction
The First Stage of Interphase
G1 – Cell growth and duplication of organelles.
The Second Stage of Interphase
S – Synthesis of DNA and DNA repair
The Third Stage of Interphase
G2 – replication of centrioles and other proteins needed for division.
The nuclear envelop is still present
G0
Cells that have temporarily or reversibly stopped dividing are said to have entered a state of pause
Prophase
a) chromosomes condense
b) centrioles migrate
c) Spindle Fiber form
Prometaphase
a) The nuclear membrane and nucleolus disappear
b) Spindle fiber make contact
Metaphase
Chromosomes align
Anaphase
a) centromeres split
b) sister chromatids are pulled apart
Telephase
a) Mitotic spindles disassemble
b) chromosomes begin to unwind
c) Nuclear envelop and nucleolus
Cytokinesis
a) Division of the cytoplasm
b) cleavage furrow forms
BRCA1 and BRCA2
Breast Cancer- tumor suppressor genes
Act as a stop sign and helps repair damaged DNA
Having a BRCA mutation results in
Cancer rates much higher,
First breast cancer 56 to 85%
Second occurrence of breast cancer 50%
Ovarian cancer up to 45%
Men with a BRCA mutation also have an increased risk for breast and prostrate cancer
Proto-oncogenes
act like an accelerator in cells
Oncogene
a mutated proto-oncogene that results in cell growth being too quick.
HER genes
a oncogene that results in about 15-20 percent of breast cancer cases