The Brain III Flashcards

(31 cards)

1
Q

In the brain, starting with the periosteum, what are the layers, including spaces

A
Periosteum
Dura mater
Subdural space
Arachnoid membrane
Subarachnoid space
Pia Mater
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2
Q

The subdural space is filled with _____ while the subarachnoid space has ______.

A

Interstitial fluid

CSF

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3
Q

In the spinal cord, starting with the periosteum, what are the layers, including spaces

A
Periosteum
Epidural space
Dura mater
Subdural space
Arachnoid membrane
Subarachnoid space
Pia Mater
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4
Q

What fills the epidural space?q

A

Fat and Loose CT

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5
Q

CSF circulates _________ and ________ the CNS.

A

Inside

Outside

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6
Q

Name the three ways CSF protects the brain

A

Mechanical
Chemical
Circulation

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7
Q

How the CSF protect the brain mechanically?

A

CSF is a shock absorbing fluid

Protects delicate tissue from jolts

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8
Q

How does CSF protect the brain chemically?

A

Provides the optimal chemical environment for brain tissue

The brain needs a specific tonic balance

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9
Q

What does the circulation of CSF do for the brain?

A

Its a medium for the exchange of nutrients and waste between blood and nervous tissue

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10
Q

To maintain homeostasis, CSF must be _________ at the ______ _______.

A

Reabsorbed

Arachnoid villi

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11
Q

The arachnoid villi are _______-like projections into the ______ ______ _______.

A

Finger

Superior sagittal sinus

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12
Q

CSF reabsorption only happens at the:

A

Arachnoid villi of the superior sagittal sinus/

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13
Q

What flows in the sinus of the dura mater?

A

Venous blood to the neck veins

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14
Q

What are the 5 dural sinuses beachy wants us to know?

A
Superior sagittal sinus
Inferior sagittal sinus
Straight sagittal sinus
Transverse sagittal sinus
Sigmoid sagittal sinus
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15
Q

In some places, the meningeal dura mater extends inwards to form flat _____ that anchor the brain to the skull.

A

Septa

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16
Q

The brain and spinal cord ______ in the bony cranium

17
Q

Using a car as an analogy, dura mater is like a ________, and the CSF is like an ______.

A

Seat belt

Air bag

18
Q

Name the sinus in the falx ceribri

A

Superior sagittal sinus

Inferior sagittal sinus

19
Q

What is hydrocephaly?

A

An abnormal accumulation of CSF in the brain that puts pressure on the brain

20
Q

In an infant, hydrocephaly can be treated how?

A

The installation of a shunt

21
Q

Meningitis is prevalent in this population and is caused by:

A

3-mo to 2 years

A variety of bacteria or viruses

22
Q

Meningitis invades the _____ following an infection of the ______ or _____.

A

CNS

Nose or throat

23
Q

Sx of meningitis include:

Diagnosis comes from:

A

Sx: high fever, stiff neck, intense headache

CSF examined for bacteria or WBC

24
Q

The blood brain barrier consists of what 3 layers?

A
  1. Endothelium with tight junctions
  2. Basement membrane
  3. Perivascular feet of astrocytes
25
In the BBB what are responsible for chemical secretion?
Astrocytes
26
The BBB is highly permeable to:
Water, glucose, lipid-soluble substances: O2, CO2, Alcohol, caffeine, nicotine, anesthetics, heroin
27
The BBB is not permeable to:
proteins, antibiotics
28
How do clinicians get drugs past the BBB to the brain area?
Precursors or nasal sprays through the nasal area
29
How do clinicians treat Parkinson's in regards to getting meds through the BBB?
Patients need dopamine, which cannot pass through the BBB. L-dopa, precursor to dopamine, is prescribed as it can cross the BBB.
30
At rest, the brain consumes _____% of the O2 breathed in.
20%
31
In most cases, a 1-2 min interruption in O2 puts the patient in a state of ____________, after 4 min the patient is __________ __________.
Unconscious | Brain dead