the central dogma of molecular bio Flashcards
(37 cards)
what is the central Dogma of molecular bio used to describe what ?
describes the path that genetic info takes in the cell
what is a gene
the sequence of dna nucléotides required to tell the cell how to make one type of protein.
genome is:
collection of all the gens found in the dna of species
Dna nucléotides (atgc) name what the process is ,location and enzyme.
1- transcription
2-nucleus
3-RNA polymerase
*uses the law of complementary base pairs
Rna nucléotides (AUCG) name what the process is ,location and enzyme.
1-transcription
2-cytosol and rough endoplasmic reticulum
3- ribosom
*uses genetic code = combos of 3 RNA nucleotides called codons specify each amino acids
Proteins what are they made of :
combinations of 20 different amino acids
what are the differences between DNA and RNA :
1-nucléotide subunits utilize different sugars (DNA = deoxyribose)(RNA ribose)
2-molecules take on different shapes : (DNA double stranded )(RNA id single stranded)
3- one nucleotide base is different : (DNA= ATCG)(RNA=AUCG)
Genetic code : what is the start codon :
AUG
*specifies methionine but also tells the ribosome where to start
what are the stop codons
UAA, UAG, and UGA
* tells ribosome where to stop .
structure of gene
see page 2 of unit 3
DNA: AAATACTTGGCAACT
what is the start and stop codon
RNA : UUUAUGAACCGUUGA
Question: What is the Central Dogma of molecular biology?
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Answer: The Central Dogma of molecular biology describes the path that genetic information takes in the cell
Question: What is a gene according to the Central Dogma description?
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Answer: A gene is the sequence of DNA nucleotides required to tell the cell how to make one type of protein
Question: What is a genome?
Answer: A genome is a collection of all the genes found in the DNA of a species
Question: Describe the process of transcription (DNA to RNA), including location and enzyme.
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Answer: Transcription is the process from DNA to RNA. It occurs in the Nucleus, uses the enzyme RNA polymerase, and follows the law of complementary base pairs
Question: Describe the process of translation (RNA to Protein), including location and enzyme.
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Answer: Translation is the process from RNA to Protein. It occurs in the Cytosol and rough ER, and uses a ribosome
Question: What is a mutation?
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Answer: A mutation is a change to the nucleotide sequence of DNA or RNA.
Question: Are mutations random?
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Answer: Yes, mutations are random
Question: How do mutations relate to adaptation and evolution?
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Answer: Mutations allow adaptation to the environment (evolution)
Question: Are mutations mostly harmful, neutral, or beneficial?
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Answer: Mutations are mostly harmful, sometimes neutral, [and] rarely beneficial
Question: What are the types of mutations based on the change to the nucleotide sequence?
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Answer: Based on the change to the nucleotide sequence, types of mutations are substitution, deletion, and insertion
Question: Describe a substitution mutation.
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Answer: Substitution is changing one or more nucleotides for the same number of new nucleotides
Question: Describe a deletion mutation.
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Answer: Deletion is when one or more nucleotides is removed from the sequence.
Question: Describe an insertion mutation.
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Answer: Insertion is when one or more nucleotides are added to the sequence.