the central dogma of molecular bio Flashcards

(37 cards)

1
Q

what is the central Dogma of molecular bio used to describe what ?

A

describes the path that genetic info takes in the cell

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2
Q

what is a gene

A

the sequence of dna nucléotides required to tell the cell how to make one type of protein.

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3
Q

genome is:

A

collection of all the gens found in the dna of species

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4
Q

Dna nucléotides (atgc) name what the process is ,location and enzyme.

A

1- transcription
2-nucleus
3-RNA polymerase
*uses the law of complementary base pairs

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5
Q

Rna nucléotides (AUCG) name what the process is ,location and enzyme.

A

1-transcription
2-cytosol and rough endoplasmic reticulum
3- ribosom
*uses genetic code = combos of 3 RNA nucleotides called codons specify each amino acids

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6
Q

Proteins what are they made of :

A

combinations of 20 different amino acids

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7
Q

what are the differences between DNA and RNA :

A

1-nucléotide subunits utilize different sugars (DNA = deoxyribose)(RNA ribose)
2-molecules take on different shapes : (DNA double stranded )(RNA id single stranded)
3- one nucleotide base is different : (DNA= ATCG)(RNA=AUCG)

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8
Q

Genetic code : what is the start codon :

A

AUG
*specifies methionine but also tells the ribosome where to start

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9
Q

what are the stop codons

A

UAA, UAG, and UGA
* tells ribosome where to stop .

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10
Q

structure of gene

A

see page 2 of unit 3

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11
Q

DNA: AAATACTTGGCAACT
what is the start and stop codon

A

RNA : UUUAUGAACCGUUGA

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12
Q

Question: What is the Central Dogma of molecular biology?
*

A

Answer: The Central Dogma of molecular biology describes the path that genetic information takes in the cell

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13
Q

Question: What is a gene according to the Central Dogma description?
*

A

Answer: A gene is the sequence of DNA nucleotides required to tell the cell how to make one type of protein

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14
Q

Question: What is a genome?

A

Answer: A genome is a collection of all the genes found in the DNA of a species

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15
Q

Question: Describe the process of transcription (DNA to RNA), including location and enzyme.
*

A

Answer: Transcription is the process from DNA to RNA. It occurs in the Nucleus, uses the enzyme RNA polymerase, and follows the law of complementary base pairs

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16
Q

Question: Describe the process of translation (RNA to Protein), including location and enzyme.
*

A

Answer: Translation is the process from RNA to Protein. It occurs in the Cytosol and rough ER, and uses a ribosome

17
Q

Question: What is a mutation?
*

A

Answer: A mutation is a change to the nucleotide sequence of DNA or RNA.

18
Q

Question: Are mutations random?
*

A

Answer: Yes, mutations are random

19
Q

Question: How do mutations relate to adaptation and evolution?
*

A

Answer: Mutations allow adaptation to the environment (evolution)

20
Q

Question: Are mutations mostly harmful, neutral, or beneficial?
*

A

Answer: Mutations are mostly harmful, sometimes neutral, [and] rarely beneficial

21
Q

Question: What are the types of mutations based on the change to the nucleotide sequence?
*

A

Answer: Based on the change to the nucleotide sequence, types of mutations are substitution, deletion, and insertion

22
Q

Question: Describe a substitution mutation.
*

A

Answer: Substitution is changing one or more nucleotides for the same number of new nucleotides

23
Q

Question: Describe a deletion mutation.
*

A

Answer: Deletion is when one or more nucleotides is removed from the sequence.

24
Q

Question: Describe an insertion mutation.
*

A

Answer: Insertion is when one or more nucleotides are added to the sequence.

25
Question: What are the types of mutations based on the effect on the protein's amino acid sequence? *
Answer: Based on the effect on the protein's amino acid sequence, types of mutations are silent mutation, missense mutation, and nonsense mutation
26
Question: What is a silent mutation? *
Answer: A silent mutation is when the amino acid sequence is unchanged.
27
Question: What is a missense mutation? *
Answer: A missense mutation is when the amino acid sequence does change.
28
Question: What is a nonsense mutation? *
Answer: A nonsense mutation is when the mutation creates a premature stop codon
29
Question: What is phenotype? *
Answer: Phenotype is the Observable or measurable characteristic.
30
Question: What is genotype?
Answer: Genotype is the alleles inherited
31
Question: How is phenotype related to genotype and environment? *
Answer: phenotype = genotype + environment
32
Question: What does homozygous mean? *
Answer: Homozygous is when an organism has the same allele of a gene on both homologous chromosomes
33
Question: What does heterozygous mean? *
Answer: Heterozygous is when an organism has two different alleles of a gene.
34
Question: What is the relationship between dominant and recessive alleles? *
Answer: Some alleles are dominant, and they coverup the effects of recessive alleles.
35
Question: What phenotype ratio did Mendel observe in his F2 cross for a single gene? * .
Answer: Mendel's second experiment (F2 cross) showed a 3:1 ratio
36
Question: In the context of inheritance, what does "autosomally" mean?
Answer: "autosomally" means Genes found on autosomes (All chromosomes except sex chromosomes)
37
Question: In the context of inheritance, what does "unlinked" mean for genes?
Answer: "unlinked" means genes found on different types of chromosomes.