The lymphatic system Flashcards

1
Q

what is The lymphatic system?

A

it is a network of tissues and organs
* It plays a key role in the immune system, fluid balance, and absorption of fats and fat-soluble nutrients

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2
Q

what The lymphatic drainage

A
  • It is the second vascular system
  • Capillaries are very permeable so fluid leaks out
  • Whole blood never leaks the capillaries
  • Leukocytes, water and nutrients do
  • Fluid collects in the surrounding tissue
  • Interstitial fluid
  • Some fluid returns back to the capillaries
  • The rest is picked up by lymphatic capillaries
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3
Q

what is Lymphatic capillaries

A
  • Have larger pores in their walls than blood capillaries
  • Pressure inside is lower
  • Excess tissue fluid drains into them
  • Fluid known as lymph * Lymph is filtered by lymph nodes
  • Collected by lymphatic ducts
  • Enters the left and right subclavian veins
  • Returns to blood stream
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4
Q

Structure of The lymphatic system includes

A
  • Lymphatic capillaries
  • Lymphatic vessels
  • Lymphatic nodes
  • Lymphatic ducts
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5
Q

what is Lymph

A

-Lymph is derived from interstitial fluid
-Composition continually changes as the blood and surrounding cells continue exchanging substances
-Mixture of fats and lymph is called chyle
-Lymph contains less proteins than plasma
-96% water, 4% solids

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6
Q

where is the thoracic duct located

A

near the left subclavian vein

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7
Q

what is the thoracic duct

A

Largest lymphatic vessel.
40cm long.
Extends from the 2nd lumbar vertebra to the root of the neck. Empties into the subclavian vein .
Collects and drains lymph from the left side of the head, neck, both lower limbs, left side of the trunk and left arm.

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8
Q

where is the right lymphatic duct located

A

near the right subclavian vein

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9
Q

what is the right lymphatic duct

A

Only 1.5cm long. Located at the root
of the neck. Empties into the right
subclavian vein. Receives all the
drained lymph from the right side of
the ehad, chest, neck and right arm

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10
Q

what is Lymph circulation

A

Through the contraction of skeletal muscle which collapses the vessels
* Valves prevent backflow
* A slight oncoming pressure from the tissue fluids
* Movement of the lymph towards the thorax during inspiration
* Negative pressure helps pull the lymph upwards into the lymphatic ducts

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11
Q

what is Oedema

A
  • Obstruction of lymph flow
  • Swelling of tissues due to the collection of excess fluid
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12
Q

what is Lymphatic capillaries structure

A
  • Vessels which work with blood to collect excess tissue fluid
  • Unite to form lymphatic vessels
  • Fine, blind-ended permeable tubes
  • Composed of a single layer of endothelial cells
  • Less firmly attached to one another than capillaries
  • Occur in all spaces between tissues
  • More variable in diameter than blood capillaries
  • Not found in the neural tissue of the central nervous system, in cartilage or in the cortex of the thymus gland
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13
Q

structure of Lymphatic vessels

A
  • Have valves to keep moving in the direction toward the heart
  • Valves consist of a double layer of lining membrane and:
  • An outer later of fibrous tissue
  • A middle layer of muscular and elastic tissue
  • An inner layer of endothelial cells
  • Collect lymph from lymphatic capillaries and convey the lymph towards the heart
  • All lymph vessels pass through one or more lymph nodes
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14
Q

what are Lymph nodes

A
  • All small and medium sized lymph vessels open into lymph nodes
  • Located throughout the body
  • An afferent vessel transports lymph to the node
  • An efferent vessel transports the filtered lymph back to the system
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15
Q

Lymph nodes structure

A
  • Nodes are made of lymphatic tissue
  • Lymphatic tissue is surrounded by a wall of tough white fibrous tissue
  • Trabeculae are inward strands of fibrous tissue which offer support
  • Lymph nodes vary in size
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16
Q

Lymph nodes function

A
  • Lymph nodes filter the lymph
  • They remove and destroy harmful organisms, tumour cells, damaged or dead tissue cells, large molecules and toxic substances
  • Prevent toxic materials from reaching the bloodstream
  • If not it could cause septicaemia
  • Produce new lymphocytes
  • Lymphatic tissue cells, the B lymphocytes may become activated and produce antibodies
  • This produces memory B lymphocytes
17
Q

what is Septicaemia

A
  • Causes the lymph node to swell
  • In severe cases it may cause cell destruction and
    an abscess on the node
  • Abscesses are localized collections of pus caused
    by infections
  • An abscess may require drainage and antibiotic treatment.
18
Q

what lymphatic tissue consist from

A
  • Contains many types of cells
  • Phagocytes
  • Lymphocytes
  • Dividing cells which give rise to new lymphocytes
19
Q

what are Phagocytes

A

White blood cells that
engulf and destroy harmful
pathogens and bacteria

20
Q

what are Lymphocytes

A

White blood cells that
produce antibodies (B
lymphocytes)

21
Q

what is Spleen

A
  • Produces and destroys cells
  • Non essential organ
  • Varies in size and shape
  • Sometimes removed due to damage after accidents
  • Lies on the upper left hand side of the abdomen
22
Q

Spleen - functions

A
  • Forms new lymphocytes
  • Destroys thrombocytes and erythrocytes
  • Helps remove foreign particles from the circulation
  • Helps fight infection
  • Acts as a blood reservoir
  • Blood sinuses within the spleen normally hold a large amount of blood which is pushed into general circulation when the spleen contracts
  • Contractions normally 2-3 times/minute
  • During exercise or shock = faster and longer contraction
23
Q

Hodgkin’s lymphoma

A
  • A cancer of the lymphatic system
  • Cells grow abnormally and may spread
  • Marked by the presence of Reed-Sternberg cells
    – large abnormal lymphocytes that contain more than 1 nucleus
  • Typically begins in the upper body
24
Q

Non-hodgkin lymphoma

A
  • A cancer in the lymphatic system
  • Causes the cells to abnormally reproduce eventually causing tumours to grow
  • May arise in the lymph nodes