The Nervous System Flashcards

1
Q

The nervous system is Divided into two parts

A
  • Central nervous system-Main unit and connected to the rest of the body
  • Peripheral nervous system-Carries information to and instructions from the brain
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2
Q
  • Nervous tissue is composed of
A
  • Nerve cells – neurons
  • Contain fibres which transmit nerve impulses
  • Neuroglia– connective tissue
    which supports neurons
  • Only found in the nervous system
  • Does not transmit nerve impulses
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3
Q

what are Neurons

A
  • Basic units of the nervous system
  • Long and narrow cells– up to 1m
  • Easily damaged by toxins and lack of oxygen
  • Not usually replaced when they die
  • Some may have the ability to regenerate
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4
Q

Neurons composed of

A
  • Cell body
  • Centre of the neuron. Contains the nucleus, cytoplasm and organelles e.g. mitochondria
  • Dendrites
  • Nerve fibres. Transmit nerve impulses TO the cell body
  • Most neurons have several dendrites
  • Axon
  • A long single nerve fibre
  • Transmits nerve impulses AWAY from the cell body
  • Neurons generally have one axon
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5
Q

what is * Myelin sheath

A
  • Made of a white, fatty substance which covers the axon
  • Protects it from pressure and helps speed up nerve conduction
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6
Q

what is * Neurilemma

A
  • A fine delicate membrane which surrounds the myelin sheath and helps regenerate nerve cells
  • Composed of the cytoplasm and the nuclei of the Schwann cells which lie outside the myelin sheath
  • Only found in the peripheral nervous system
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7
Q

what are Nodes of Ranvier

A
  • Gaps in the myelin sheath along the nerve
  • Speed up the passage of nerve impulses along the fibre
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8
Q

what are * Synapse

A
  • A point where one neuron meets another
  • Chemical messenger fills the gap and enables the impulse to be transmitted
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9
Q
  • End feet/axon terminals
A
  • Ends of the fibrils that make the axon more expanded
  • Pass on the impulse from the axon to the dendrites of the next neuron
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10
Q

Types of neurons – by function

A
  • Sensory neuron – afferent neurons
  • Transmit impulses to the CNS so it can be processed
  • Motor neuron – efferent neurons
  • Transmit impulses to muscles, organs and glands
  • Interneuron – found only in the CNS
  • Connect one neuron to another
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11
Q

Types of neurons – by structure

A
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12
Q

basic Function of Neurons

A
  • Receive signals (or information).
  • Integrate incoming signals (to determine whether or
    not the information should be passed along).
  • Communicate signals to target cells (other neurons or
    muscles or glands).
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13
Q

all Nerves and nervous tissue

A
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14
Q

The nerve impulse – action potential

A
  • Nerve cells transmit and receive nerve impulses throughout the body
  • Impulses are created in response to internal or external stimuli
  • Temperature, pressure, chemicals
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15
Q

Resting membrane potential

A
  • Positively charged sodium and potassium ions are present inside and outside the cell
  • In a resting axon
  • The concentration of sodium ions is lower inside the cell
  • The concentration of potassium ions is higher inside the cell
  • Due to
  • Sodium potassium pump
  • Many leakage channels for potassium
  • Few leakage channels for sodium
  • Result
  • Inside of cell is more negative than the outside
  • Chemical gradients for Na+ and K+ are created
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16
Q

Sensory receptors – AP generation

A
  • Stimuli are detected by sensory receptors
  • The axon becomes temporarily more permeable to sodium ions which rush in
  • The inside of the cell becomes more positive – depolarisation
  • This reaches a threshold and then it starts becoming more negative – repolarisation
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17
Q

Voltage gated channels

A
  • Along the axon, there are voltage gated channels for both sodium and potassium
  • These open when a threshold voltage is reached
  • As they open, ions passively flow along the chemical gradient until a threshold to close is reached
  • Voltage channels close and become inactivated
  • The will not open for some time – refractory period
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18
Q

Steps of an action potential

A
  1. Start = RMP = -70mv
  2. Disturbance causes threshold voltage for Na+ voltage gated channels to open - -55mv
  3. Na+ voltage gated channels open
  4. Na+ rushes in – rapid depolarisation till +30mv
  5. Na+ channels close, K+ channels fully open
  6. K+ rushes out – repolarisation
  7. Overshoot – K+ continues to rush out beyond RMP since they close very slowly – hyperpolarisation –85mv
  8. K+ channels close
  9. Na+/K+ pump restores RMP and returns ions to their original positions
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19
Q

Refractory periods

A
  • Why does an action potential proceed only one way?
  • The answer lies in the refractory period
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20
Q

action potential In the case of myelinated axons

A
  • The action potential is generated only at the nodes of Ranvier
  • Saltatory conduction
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21
Q

Synapses

A
  • Nerve impulses travel in one direction
  • The impulse crosses the synapse from the axon terminal of the first neuron to the dendrites of the next neuron
  • In between neurons, a neurotransmitter carries the message across the synapse
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22
Q

Divisions of the
nervous system

A
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23
Q

The central nervous system

A
  • The brain
  • Fills the cranium
  • Stops developing in the 15th year of life
  • Main mass exercising control over the body
  • Three section
  • Cerebrum
  • Cerebellum
  • Brain stem
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24
Q

The cerebrum - structure

A
  • The largest part of the brain
  • Divided into two cerebral hemispheres – left & right
  • The outer layer is made of folds of grey matter
  • Folds increase surface area
  • There is white matter inside the grey matter
  • White matter is composed of fibres which connect different parts
    of the brain together
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25
Q

The cerebrum - functions

A
  • Controlling voluntary movement
  • Interpreting and perceiving
    conscious sensations like pain, heat and cold
  • Controlling mental activity eg memory, intelligence and reasoning
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26
Q

The cerebellum -structure

A
  • Also known as the small brain
  • Positioned in the posterior cranial fossa behind the pons Varolii, below the cerebrum and over the medulla oblongata
  • Consists of two hemispheres, grey matter on the surface, white matter underneath
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27
Q

The cerebellum - functions

A
  • Co-ordinating muscular activity
  • Subconsciously controlling and maintaining muscle tone and posture
  • Maintaining balance and equilibrium of the body
28
Q

Hypothalamus - structure

A
  • Situated deep within the cerebrum at the top of the brainstem with the pituitary attached to its base
29
Q

Hypothalamus - functions

A
  • Helps with the regulation of body temperature, water balance and metabolism
  • Centre for drives and emotions e.g. thirst, apetite, sex, pain and pleasure
  • Regulates the pituitary gland forming the main link between the nervous and endocrine systems
  • Secretes oxytocin and antidiuretic hormone/vasopressin (ADH) which are stored in the pituitary
30
Q

The brain stem Consists of three parts

A
  • Midbrain
  • Pons Varolii
  • Medulla oblongata
31
Q

Midbrain

A
  • Lies between the cerebrum and cerebellum and above the pons Varolii
  • About 2cm long
  • Consists of nerve cells and fibres
  • Acts as a relay station of the brain
  • Transmits messages to and from the spinal chord, cerebrum and cerebellum
32
Q

Pons Varolii

A
  • Situated in front of the cerebellum, below the
    midbrain and above the medulla oblongata
  • Consists of nerve fibres which bridge the gap between the two hemispheres of the cerebellum
  • Transmits messages to and from the spinal cord and cerebrum
33
Q

Medulla oblongata – structure

A
  • Lowest part of the brainstem
  • Located above the spinal chord and below the pons Varolii
  • Construction is different from the cerebrum and cerebellum
  • Has white matter on the surface and grey matter in the centre
  • Known as a vital centre
  • Controls the actions of the heart and lungs
34
Q

Medulla oblongata - functions

A
  • Cardiac centre
  • Controls the rate and strength of heart contraction
  • Respiratory centre
  • Controls the rate and depth of breathing
  • Vasomotor centre
  • Controls vasoconstriction and vasodilation
  • Reflex centre
  • Responds to irritants
  • Controls vomiting, coughing, sneezing and swallowing
35
Q

The spinal chord - structure

A
  • Extends from the medulla oblongata through the spinal vertebrae ending at the first lumbar vertebra
  • Consists of white matter on the surface and grey matter inside
  • Branches off into 31 pairs of spinal nerves ant part of 1 cranial nerve
36
Q

The spinal cord - functions

A
  • Carries motor and sensory nerve fibres along its length
  • Sends messages to and from the body and brain
37
Q

The meninges

A
  • Membranes which protect the whole of the central nervous system.
  • Three layers
  • Dura mater
  • Arachnoid mater
  • Pia mater
38
Q

Dura mater (outer membrane)

A
  • A double layer of tough, fibrous membrane
  • It is thick and inextensible
  • Periosteal layer
  • Outer layer forms the periosteum of the skull
  • Meningeal layer
  • Inner layer (first protective covering of the brain) continues as the spinal dura mater as far down as the sacrum
39
Q

Arachnoid mater

A
  • A delicate membrane
  • Located under the dura mater and above
    the pia mater
  • Merges with the dura mater and covers the spinal chord as far as the sacrum
  • Connects to the sub-arachnoid space found between the arachnoid mater and the pia mater
  • Sub-arachnoid space
  • Cushions the brain
  • Filled with cerebrospinal fluid
40
Q

Pia mater

A
  • Thin vascular membrane
  • Tightly adhered to the surface of the brain and spinal chord
  • Follows the contours of the brain (gyri and fissures)
  • Continues along the length of the spinal chord
  • Highly vascularised. Supplies blood to the brain and spinal chord
41
Q

Ventricles

A
  • Four cavities inside the brain
  • Two lateral ventricles. One on each side of the cerebral cortex
  • The lateral ventricles are continuous with the 3rd ventricle
  • The 3rd ventricle is continuous with
    the 4th ventricle which runs along the brainstem
  • Contain cerebrospinal fluid
42
Q

Cerebrospinal fluid

A
  • Cerebrospinal fluid is produced by the lining of the ventricles
  • Within choroid plexuses
  • It is clear and colourless
  • Resembles blood plasma in composition
  • Contains protein, glucose salts and other substances
  • Secreted into the ventricles and circulates around the whole brain and spinal chord
  • Reabsorbed into the venous sinuses of the body through the arachnoid mater
43
Q

Cerebrospinal fluid - functions

A
  • Protects the brain and spinal chord
  • Forms a cushion between the bony cavities and nerves acting as a shock absorber
  • Keeps the pressure around the brain and spinal chord constant
  • Being immersed in CSF the net weight of the brain is reduced to 26g.
  • This prevents excessive pressure on the base of the brain
  • Chemical stability. CSF creates an environment to allow for proper functioning of the brain
  • Transports nutrients and removes wastes and toxic substances
44
Q

Peripheral nervous system

A
  • Concerns all the nervous system outside the central nervous system
  • Contains motor and sensory nerves which transmit to and from the body to the CNS
  • Consists of 12 pairs pf cranial nerves and 31 pairs of spinal nerves
45
Q

Cranial nerves

A
  • 12 paired nerves which arise directly from the brain
  • The first 2 (I-II) nerves (olfactory and optic) arise from the cerebrum
  • Rest emerge from the brain stem
  • Names relate to their function
  • Numerically identified in roman numerals (I-XII)
46
Q

Trigeminal (V)

A

Opthalmic
* Sensory nerves supplying the lachrymal glands, conjunctive of the eyes, eyelids, forehead, anterior part of the scalp and mucuous membranes of the nose
Maxillary
* Sensory nerves supplying the lower eyelids, upper gums, upper teeth and cheeks
Mandibular
* Sensory and motor nerves
* Supply the teeth and gums of the lower jaw, ear and tongue. Motor supplying the muscles of mastication

47
Q

Facial (VII)

A
  • Motor supply the muscles of the facial expression
  • Sensory supply nerves of taste from the anterior part of the tongue
48
Q

Accessory (XI)

A
  • Two parts
  • Cranial – branches joining the vagus nerve to supply the pharynx and larynx
  • Spinal – branches supplying the trapezius and sternocleido mastoidi
49
Q

Spinal nerves

A
  • Begin in the spinal chord
  • Supply all parts of the body not covered by the cranial nerves
  • All are mixed nerves
  • Divided into 31 pairs
  • Cervical – 8 pairs
  • Thoracic – 12 pairs
  • Lumbar – 5 pairs
  • Sacral – 5 pairs
  • Coccygeal – 1 pair
50
Q

Spinal nerves2

A
  • Cervical and thoracic nerves are named after the vertebrae at the level they exit the spinal chord
  • Lumbar, sacral and coccygeal nerves leave the spinal chord at the level of the first lumbar vertebra and extend downwards inside the vertebral canal
  • Exit the canal at different levels depending on their destination
  • All spinal nerves except T2 to T12 branch out and regroup to form plexuses which supply different parts of the body
51
Q

Other structures

A

Cervical plexus
* Contains the 1st four cervical nerves
* Supplies the muscles of the neck, shoulder and skin
* Includes the phrenic nerve
Brachial plexus
* Includes the lower four cervical nerves and the 1st thoracic nerve
* Branches out to supply the muscles from the base of the neck to the fingertips and skin Thoracic (intercostal nerves)
* Supply the chest muscles and the main part of the abdominal wall Lumbar plexus
* Includes the 1st three lumbar nerves and part of the fourth
* Supplies the skin and muscles of the lower abdomen, thighs and groin Sacral plexus
* Includes the 4th and 5th lumbar nerves and 1st 4 sacral nerves
* Supplies muscles and skin of the pelvic area
* Main nerve is the sciatic nerve

52
Q

Function organisation of the PNS

A
53
Q

Somatic nervous system

A
  • Conducts impulses from the CNS to skeletal muscle fibres
  • The voluntary branch of the PNS
  • Allows conscious control over the contraction of skeletal muscles
54
Q

Autonomic nervous system

A
  • Conducts impulses from the CNS to cardiac and smooth muscles and glands
  • An involuntary system controlled by the hypothalamus
  • Nerves arise from the medulla oblongata
  • Divided into the sympathetic and parasympathetic
55
Q

Sympathetic

A
  • Nerves that arise from the spinal chord at the thoracic and lumbar region – thoracolumbar
  • Forms ganglia just outside the CNS
  • Nerves then extend to the organ or tissue they supply
56
Q

Sympathetic - functions

A
57
Q

Parasympathetic

A
  • Consist of nerves that arise from the brain and sacral region of the spinal chord - craniosacral
  • Form ganglia near to or inside the organ or tissue they supply
58
Q

Parasympathetic - functions

A
59
Q

Sympathetic/Parasympathetic graph

A
60
Q

what is Reflexes

A
  • A reflex is an automatic movement produced by a sensory stimulus
  • It is instant and involuntary
  • Components
    ↓A sense organ – detects the stimulus
    ↓A sensory nerve travelling from the sensory organ
    ↓The spinal chord
    ↓A motor nerve starting from the spinal chord to the motor organ
61
Q

Reflexes

A
  • Mostly protective
  • Designed to stimulate the quickest motor responses possible
  • Automatic reflexes
62
Q

sciatica

A
  • Pressure on the roots of the sciatic nerve which becomes inflamed
  • Causes pain down the back and outside of the thigh, leg and foot
  • Treatment includes. mostly non surgical options and physical therapy
63
Q

Meningitis

A
  • An infectious disease characterised by inflammation of the meninges
  • Usually caused by a bacterial infection
  • Symptoms include headache, stiff neck, fever & nausea
64
Q

Stroke

A
  • A sudden loss of consciousness
  • Due to rupture or occlusion of a blood vessel leads to a lack of oxygen in the brain
65
Q

Spina bifida

A
  • A developmental birth defect involving the neural tubes
  • A vertebra is malformed and the backbone does not form properly
66
Q

Concussion

A
  • A mild traumatic brain injury after an impact
  • Violently shaking the head and upper body can also cause concussions
  • Results in an altered mental state that may include becoming unconscious
  • Effects are usually temporary but can include headaches, problems with concentration, memory balance and coordination
67
Q

Shaken baby syndrome

A
  • Occurs when the baby is shaken violently
  • Babies have very weak neck muscles that cannot fully support their head
  • Severe shaking causes the baby’s head to move violently back and forth
  • May result in serious and sometimes fatal brain injury