The Menstrual Cycle Introduction Flashcards
(14 cards)
The development of a mature oocyte requires
the endocrine interactions of the menstrual cycle.
The length of the menstrual cycle (Latin = mensis = ‘month’) is the
number of days between the first day of menstrual bleeding of one cycle to the onset of menses of the next cycle and has an average duration of ~29.5 days or approximately one month (Figure 13).
However, on an individual basis, the actual duration of the menstrual cycle varies with only __________ of all cycling women having a 29.5 day cycle.
10%-15%
Most women who menstruate regularly have cycles that last from
25-30 days in length with older women having shorter cycles than younger women.
The key to fertility is not having a cycle length of exactly 29.5 days but consistently having cycles of the same duration. Erratic menstrual cycle lengths in the same woman are associated
with infertility.
The menstrual cycle is divided into the following two major phases:
a. The follicular phase
b. The luteal phase
The follicular phase lasts approximately 14 days during which time there is
a daily increase in follicular growth and estrogen production.
The length of the follicular phase appears to depend on the rate at which the
principal preantral follicle matures since it is the main source of estrogen and therefore a major regulator of cycle length.
Menstruation occurs at the beginning of the
follicular phase and the day on which menses first appears is considered Day 1 of the menstrual cycle.
On the 14 day of a 28-day menstrual cycle, ovulation occurs and the
follicle is transformed into the corpus luteum.
Ovulation marks the end of the
follicular phase and the beginning of the luteal phase.
The onset of the LH surge precedes
ovulation by 36 hours and LH levels peak 10 to 12 hours prior to ovulation.
The luteal phase is associated with increasing production of
progesterone and some estrogen that prepares the uterus for implantation.
The luteal phase is relatively constant in all women and will end in approximately
14 days with the appearance of menses if implantation does not occur. The cycle will repeat with the resumption of a new follicular phase.