the pregnant woman Flashcards
(110 cards)
what does estrogen do? (3)
- Endometrial growth supports early pregnancy
- Stimulates prolactin from anterior pituitary: readies breast tissue for lactation
- Contributes to a hypercoagulable state that increases risk of thromboembolic events
which hormone dominates the beginning of the menstrual cycle?
estrogen
what does progesterone do? (3)
- Increase tidal volume and alveolar minute ventilation; leads to resp. alkalosis and SOB sensation
- Esophageal sphincter tone decreases: gastroesophageal reflux— ( works with estradiol)
- Relaxes tone in ureters and bladder: hydronephrosis and risk of bacteruria
what does HCG do?
Produced by the placenta supports progesterone synthesis in corpus luteum preventing the early embryo being lost to menstruation
- (AKA supports pregnancy until the pregnancy can support itself- keeps placental supported by progesterone)
***what hormone is implicated in the insulin resistance and hyperglycemia associated with gestational diabetes?
human placental lactogen
***___ of all women with GDM will go on to have _____ ______ _____ in their lifetime
half
type 2 DM
if a woman has GDM in first pregnancy? will she likely have it in her second? what are the babies like?
yes!
babies are big
how do thyroid hormones (T3, T4, TSH) levels change in pregnancy?
fluctuate, usually normal ranges, due to HCG’s stimulation of TSH receptor
what secretes relaxin? what does it do?
Secreted by corpus luteum and placenta
- Promotes ligamentous laxity in the SI joints and pubic symphysis in preparation for passage of the fetus
when does erythropoeitin levels increase? what does this do?
Increases during pregnancy raising erythrocyte mass
- Plasma volume increases causing relative hemodilution and physiologic anemia
- CO increases but systemic vascular resistance decreases: net decrease in BP
what anatomic changes happen to the breast in pregnancy? (4)
- Moderate enlargement due to hormonal stimulation increased vascularity and glandular hyperplasia
- Nipples larger and more erectile, darker areola and pronounced Montgomery glands
- Increased venous pattern
- 2nd and 3rd trimester colostrum secretion; a nutrient rich precursor to milk
what anatomic changes happen to the uterus in pregnancy? (3)
- increases in size: Muscle cell hypertrophy
- Increase in fibrous and elastic tissue
- Development of blood vessels and lymphatic
in the ___ trimester, Uterus confined to pelvis
and Retains prior position
first
what happens to the uterus/ b/c of the uterus in the second trimester ? (4)
- 12-14 weeks uterus becomes externally palpable above pelvic brim
- Starts to invade space for bladder
- Intestines are displaced laterally
- Stretching of round ligaments- mostly on the right side
___ wks the uterus is at the umbilicus level (to of the fundus palpable here)
20
___ wks the uterus is just above the pelvic brim (tops of fundus palpable here)
12 - 14
what are the breakdown of wks between first, second, and third trimester?
first: 0-12 wks
second: 13-28 wks
third: 29-40 wks
what anatomic changes happen to the vagina in pregnancy? (3)
- Chadwick’s sign
- Vaginal walls become more deeply rugated due to thickening of mucosa and loosening of connective tissue and hypertrophy of muscle cells
- Increase in glycogen stores in epithelium = proliferation of Lactobacillus acidophilus –> decrease vaginal pH
***what is chadwick’s sign ?
- increased vascularity leads to a bluish color of vaginal walls and cervix
what happens to the cervix in pregnancy?
- Chadwick’s sign- appears cyanotic
- Hegar’s sign
- Mucus plug fills the cervical canal to protect from
outside influence (protect from bacteria)
***what is hegar’s sign?
palpable softening of the cervical isthmus
what is the first thing “to go” in delivery?
mucus plug of the cervical canal
might be able to feel ______ ______ as a small nodule that then disappears by _________
Might be able to feel corpus luteum as a small nodule then disappears by mid-pregnancy
(changes in the adnexae in pregnancy)
what happens to the external abdomen in pregnancy?
- Stria gravidarum (stretch marks)
- Linea nigra- a brownish black line along the midline
- Diastasis recti- rectus abdominis muscles may separate