The steps of renal excretion of a medication

Question 1

What are the three steps of renal excretion of a drug?

Answer 1

Filtration, secretion, and reabsorption.

Question 2

True or False: Filtration occurs in the glomerulus of the nephron.

Answer 2

True.

Question 3

Fill in the blank: The process by which substances are moved from the blood into the tubular fluid is called __________.

Answer 3

secretion.

Question 4

What is the primary site for drug filtration in the kidney?

Answer 4

The glomerulus.

Question 5

Multiple Choice: Which step of renal excretion involves the return of substances from the tubular fluid back into the blood?

Answer 5

C) Reabsorption.

Question 6

Short Answer: Name one factor that can affect drug filtration in the kidneys.

Answer 6

Blood pressure.

Question 7

What is the role of the renal tubules in drug excretion?

Answer 7

They are involved in secretion and reabsorption.

Question 8

True or False: All drugs are completely reabsorbed in the renal tubules.

Answer 8

False.

Question 9

Fill in the blank: The __________ is responsible for the majority of drug reabsorption.

Answer 9

proximal convoluted tubule.

Question 10

What is meant by passive reabsorption of drugs?

Answer 10

Drugs move back into the bloodstream without energy expenditure.

Question 11

Multiple Choice: Which of the following drugs is more likely to be secreted in the kidneys?

Answer 11

B) A drug that is highly protein-bound.

Question 12

Short Answer: What is the consequence of renal impairment on drug excretion?

Answer 12

Decreased drug clearance and potential toxicity.

Question 13

True or False: Secretion occurs primarily in the proximal tubule.

Answer 13

True.

Question 14

Fill in the blank: The __________ process helps to eliminate waste products and excess substances from the bloodstream.

Answer 14

filtration.

Question 15

What are the two types of transport involved in secretion?

Answer 15

Active transport and facilitated diffusion.

Question 16

Multiple Choice: Which of the following factors can enhance drug reabsorption?

Answer 16

A) Increased lipid solubility.

Question 17

Short Answer: How does urine pH affect drug excretion?

Answer 17

It can alter the ionization of drugs, affecting their reabsorption and secretion.

Question 18

True or False: Renal excretion is the only route of drug elimination from the body.

Answer 18

False.

Question 19

Fill in the blank: The __________ is the final product of renal excretion.

Answer 19

urine.

Question 20

What is the impact of age on renal drug excretion?

Answer 20

Age can reduce renal function, affecting drug clearance.

Question 21

Multiple Choice: Which substance is typically not filtered at the glomerulus?

Answer 21

C) Large proteins.

Question 22

Short Answer: What is the significance of understanding renal excretion in nursing pharmacology?

Answer 22

It helps in predicting drug behavior and potential toxicity.

Question 23

True or False: All drugs undergo all three steps of renal excretion.

Answer 23

False.

Question 24

Fill in the blank: The __________ process helps to maintain homeostasis by regulating fluid and electrolyte balance.

Answer 24

reabsorption.

Question 25

What is the relationship between renal clearance and drug dosing?

Answer 25

Renal clearance affects the required dose and frequency of administration.

Question 26

Multiple Choice: Which condition can lead to impaired renal excretion?

Answer 26

A) Chronic kidney disease.

Question 27

Short Answer: Why is it important to monitor renal function in patients receiving medications?

Answer 27

To prevent adverse drug reactions and ensure therapeutic efficacy.