Therapeutic Antibodies (Target & Use) Flashcards
(8 cards)
1
Q
Muromonab-CD3 (OLT3)
A
T: CD3
U: Prevent acute transplant rejection
2
Q
Digoxin Immune Fab
A
T: Digoxin
U: Antidote for dig intoxication
3
Q
Infliximab
A
T: TNF-alpha
U: think “PAIR”: Psoriatic arthritis, ankylosing spondylitis, chron’s, rheumatoid arthritis
4
Q
Adalimumab
A
T: TNF-alpha
U: Psoriatic arthritis, chron’s, rheumatoid arthritis
5
Q
Abciximab
A
T: Glycoprotein IIb/IIIa
U: Prevent cardiac ischemia in unstable angina & patients treated with percutaneous coronary intervention
6
Q
Trastuzumab
A
(Herceptin)
T: HER2
U: HER2- overexpressing breast cancer
7
Q
Rituximab
A
T: CD20
U: B-cell non-Hodgkin’s lymphoma
8
Q
Omalizumab
A
T: IgE
U: Additional line of Tx for severe asthma
