Thursday - Parathyroid Path - Krafts Flashcards Preview

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Flashcards in Thursday - Parathyroid Path - Krafts Deck (11):
1

Most common cause of symptomatic hypercalcemia?
asymptomatic?

malignancy

hyperparathyroid

2

4 types of hyperparathyroidism and their causes

primary
- ademona
secondary
- hypocalcemia from renal failure
tertiary
- autonomous parathyroids
pseudohyperparathyroidism
- PTH-related protein, from lung cancer

3

Signs of primary hyperparathyroidism

stones
- kidney
bones
- pain - overactive osteoclasts - brown tumor
groans
- GI probz
moans
- mental changes

4

Labs of of primary hyperparathyroidism

increased PTH and Calcium
decreased phosphate

5

Genetic changes that cause Parathyroid adenoma

increased PRAD 1
decreased MEN 1

6

Difference between normal tissue and parathyroid adenoma

adenoma as no fat

7

Cause of secondary hyperparathyroidism

chronic hypocalcemia
- renal failure, usually (because can't excrete phosphate)

8

tertiary hyperparathyroidism is from what

hyperfunctional autonomous parathyroid

9

Causes of hypoparathyroidism

iatrogenic
hereditary
atrophy

10

signs and symptoms of hypoparathyroid

numbness around mouth
weakness
arrythmias
no dental enamel

11

2 special signs of hypoparathyroid (hypercalcemia)

trousseau sign
- tap cheeck
chvostek sign
- bp cuff causes spasm