Thursday - Pituitary Path - Krafts Flashcards Preview

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Flashcards in Thursday - Pituitary Path - Krafts Deck (15):
1

Most Pathology of pituitary is what lobe?

Anterior

2

mnemonic for basophils in anterior pituitary

B Flat
FSH
LH
ACTH
TSH

3

Most common cause of Hyperpituitarism
other causes:

Pituitary Adenoma

destruction of end organs
hypotalmus disorders
hyperplasia of anterior lobe
carcinoma of anterior lobe

4

Findings in pituitary adenoma

no endocrine things for a while
first, visual defects (bitemporal hemi-anopsia, later fields gone) - increased ICP
hypo pit!

5

Complications of pituitary adenoma

can bleed suddenly
can be "invasive"
usually an incidental finding

6

What does a pituitary adenoma look like

highly variable, not a single description.
pleomorphic or uniform

7

Most common secretion by pituitary adenoma?
lest common?

Prolactin

TSH

8

presentation of prolactinoma?
treatment?

amenorrhea, galactorrhea

dopamine agonist

9

Groth hormone adenoma before puberty called?
after puberty?

Gigantism
- long arms and legs
Acromegaly
- mostly face and hands

10

Other complications of growth hormone adenoma

diabetes
hypertension
artritis
gastric carcinoma

11

ACTH adenoma can cause

Cushing syndrome (also disease)

Nelson syndrome (if you remove the adrenals, which you won't)

12

Causes of Hypopituitarism

Pituitary destruction
- surgery, radiation or adenoma that's too big

ischemic necrosis
- Sheehan syndrome from hemorrhage in pregnancy

Empty Sella Syndrome

Pituitary apoplexy
- sudden infarct, can be deadly

13

Clinical presentation of of hypo pit

decreased everything
-GH --> weakness
-FSH/LH --> no libido
-PL no lactation
-TSH - hypothyroid
-ACTH - adreanal isufficiency

14

2 types of Diabetes insipidus
due to?
Blood is hypo or hypertonic?

Central, nephrogenic
decreased ADH (or don't respond to it)
- trauma, tumor, alcohol
Hyper

15

SIADH due to:
Blood is hypo or hypertonic?
what cancer causes it?

increased ADH
hypotonic
small cell lung cancer