thyroid Flashcards
(29 cards)
hypothalamus to thyroid hormones
hypothalamus releases TRH, pituitary releases TSH, thyroid releases T3 and T4
Overactive thyroid symptoms:
Increased appetite and weight loss Palpitations, Tremor, Anxiety, Tachycardia Heat intolerance, Sweating Diarrhoea, Amenorrhoea, Oligomenorrhoe Palmar erythema, Myopathy Lid retraction, Exophthalmos
Exophthalmos
abnormal protrusion of the eyeball
things which increase the risk of thyroid eye disease
graves
smoking
symptoms of thyroid eye disease
swelling above and below, redness of lids and whites, bulging
blurred, double, aching
where do the eyes ache in thyroid eye disease
behind the eye
on movement
graves
production of IgG autoantibodies directed against the thyrotropin receptor on thyroid
management of graves
carbimazole and propylthiouracil
how does carbimazole work
suppresses production of thyroid hormone
when is PTU prefered
carbimazole
how does PTU work
it suppresses the production of thyroid hormone and blocks peripheral conversion of T4 to T3
carbomazole patient gets fever/sore throat what do you do
stop medication as they can get agranulocytosis
treatment after recurrence after carbomazole/agranulocytosis
radioiodine therapy or total thyroidectomy
complications of total thyroidectomy
voice alteration
parathyroid resection
most common cause of hypo
autoimmune
hype treatment
levothyroxine
Drugs that interfere is the absorption of thyroxine
Ferrous sulphate
Calcium carbonate
PPI
calcium carbonate
antacid
Drugs that increase the turnover of thyroxine
Rifampicin
Phenytoin
Carbamazepine
Rifampicin
antibiotic
Phenytoin
anticonvulsant
Carbamazepine
anticonvulsant
when to take levothyroxine
empty stomach
goitre
enlarged thyroid
