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Biomechanics Exam 1 > Tissue Compostition > Flashcards

Flashcards in Tissue Compostition Deck (22):
1

What are the four primary tissue components?

collage
Elastic
Ground substance
water

2

How many different types of collagen?

15

3

This tissue has continuous metabolic turnover through growth to maturity.

collagen

4

When do the collagen fibers become more stable?

At maturity

5

Collagen molecules are secreted and synthesized by what?

fibroblasts

6

Collagen molecules align in what fashion and where?

Parallel,
In the extracellular matrix

7

How far can collage stretch without breaking?

110% of original length

8

How does collagen change under tension?

Increase ligament strength and size.

9

How does collagen increase in ligament size during tension?

Increase in
# of collagen fibrils,
fibril diameter,
cross-linking,
fibril packing density.

10

What things decrease with degenerative ligament changes? (5 things)

Diameter
Density
Number
Mass
metabolism

11

During immobilization, what happens at the ligament-bone junction?

-Increase osteoclast activity
-bone restoration
-Disruption of pattern of diffusion of ligament fibers into the bone

12

Elastic can stretch _____% of original length without breaking.

150

13

What happens to elastic with age?

Lost resiliency
Fragmentation and fraying
Calcification
Increased # of cross-links

14

Ground substance aka

Cementing substance

15

What is amorphous gel like substance surrounding the cells?

Ground substance

16

Water is ______% of the total connective tissue content.

60-70%

17

What is the protein or peptide which the GAGs are covalently attached to?

proteoglycan

18

What are the four major GAGs?

Hyaluronic acid
Chondroitin-4-sulfate
chondroitin-6-sulfate
dermatan sulfate

19

What is it when water moves to areas of high salute concentration?

osmosis

20

What is a powerful lubricant?

Water + hyaluronic acid

21

Water maintains what between collagen fibers?

CRITICAL DISTANCE

22

What two things does water do?

Allows free gliding
Prevents excessive cross-linking