Tissue Self Assess Flashcards

(54 cards)

1
Q

Define tissue.

A

A group of structurally and functionally similar cells from the same origin that work together to perform a specific function.

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2
Q

What is histology?

A

The branch of biology and medicine that studies the microscopic structure of tissues.

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3
Q

What is histopathology?

A

The microscopic examination of tissues to study the manifestations of disease.

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4
Q

Discuss the importance of histology in healthcare.

A
  • Disease Diagnosis
  • Guiding Treatment
  • Monitoring Therapy
  • Understanding Physiology
  • Research and Drug Development
  • Forensic Investigations
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5
Q

What do you understand by the term ‘germ layers’?

A

The 3 primary layers of cells formed during the early stages of embryonic development that give rise to all the tissues and organs of the body.

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6
Q

What are the three germ layers?

A
  • Ectoderm – outermost layer
  • Mesoderm – middle layer
  • Endoderm – innermost layer
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7
Q

What are the four primary adult tissue types?

A
  • Epithelial tissue
  • Connective tissue
  • Muscle tissue
  • Nervous tissue
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8
Q

From which germ layer is epithelial tissue derived?

A

Ectoderm, Mesoderm, Endoderm

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9
Q

From which germ layer is connective tissue derived?

A

Mesoderm

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10
Q

From which germ layer is muscle tissue derived?

A

Mesoderm

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11
Q

From which germ layer is nervous tissue derived?

A

Ectoderm

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12
Q

What do tight junctions do?

A

Form a seal for barrier and polarity control.

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13
Q

What is the function of adherens junctions and desmosomes?

A

Provide mechanical stability, ideal for tissues under mechanical stress.

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14
Q

What do hemidesmosomes do?

A

Anchor cells to the extracellular matrix (ECM), important for tissue integrity.

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15
Q

What is the function of gap junctions?

A

Enable cell communication, essential in synchronized activity.

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16
Q

What junctions are found in the urinary bladder epithelium?

A

Tight junctions, desmosomes, and adherens junctions.

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17
Q

Which type of cellular junction is prominent in cardiac muscle cells?

A

Gap junction.

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18
Q

What type of cell junction is most prominent in the gastrointestinal (GI) tract?

A

Tight junctions.

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19
Q

Epithelial cell junctions that restrict extracellular movement of molecules are:

A

Tight junctions.

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20
Q

Epithelial cell junctions that maintain tissue integrity and strength are:

A

Desmosomes.

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21
Q

Epithelial cell junctions that allow the passage of small molecules between adjacent cells are:

A

Gap junctions.

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22
Q

How is epithelium classified based on the number of cell layers?

A
  • Simple epithelium: Single layer
  • Stratified epithelium: Multiple layers
  • Pseudostratified epithelium: Appears multi-layered
23
Q

What are the cell shapes in epithelial tissue?

A
  • Squamous
  • Cuboidal
  • Columnar
  • Transitional
24
Q

Do epithelial tissues have polarity?

A

Yes, they exhibit polarity essential for directional secretion, absorption, and selective transport.

25
Are epithelial cells loosely or closely packed?
Closely packed.
26
What is the layer that epithelial cells sit on?
Basement membrane.
27
Are epithelial tissues vascular?
No, they are avascular.
28
How do epithelial tissues get nutrients?
Via diffusion from capillaries in the underlying connective tissue.
29
Do epithelial tissues have a nerve supply?
Yes, they contain sensory nerve endings.
30
List multiple functions of epithelial tissues.
* Protection * Absorption * Secretion * Excretion * Filtration * Sensation
31
Do epithelial tissues have excellent regeneration capacity?
Yes, due to rapid cell division and replacement.
32
Describe the structural features of keratinized stratified squamous epithelium.
* Surface cells: Dead, anucleate, filled with keratin * Keratin layer: Present * Function: Protection from dehydration and abrasion
33
Describe the structural features of non-keratinized stratified squamous epithelium.
* Surface cells: Alive, flat, with nuclei * Keratin layer: Absent * Function: Protection in moist areas
34
How does a mucus-thinning drug help in respiratory infections?
Restores normal mucus function, helping clear debris and heal lungs.
35
What are the three modes of secretion in exocrine glands?
* Merocrine * Apocrine * Holocrine
36
What is the mechanism of merocrine secretion?
Secrete by exocytosis without loss of cellular material.
37
What is the mechanism of apocrine secretion?
Secrete by pinching off part of the cytoplasm.
38
What is the mechanism of holocrine secretion?
Release product by rupture and death of entire cell.
39
What is a matrix in connective tissue?
The non-living extracellular material between cells that determines tissue characteristics.
40
What is the composition of the matrix?
* Ground Substance * Fibers
41
Does the matrix vary in different types of connective tissue?
Yes, it varies significantly.
42
What are the main cells for loose connective tissue?
* Fibroblasts * Adipocytes * Mast cells
43
What is the main cell type for cartilage?
Chondrocytes.
44
What type of cartilage is the strongest?
Fibrocartilage.
45
What makes fibrocartilage the hardest?
Its dense collagen fiber content.
46
What are the distinctive characteristics of epithelial tissues compared to connective tissues?
* Epithelial: Polarity, little ECM, avascular * Connective: No polarity, abundant ECM, usually vascular
47
What happens to fat cells during weight loss?
Fat cells shrink in size as stored lipids are used for energy, but the number of fat cells remains the same.
48
Why do fat cells tend to refill after weight loss?
Shunken fat cells remain in place and are primed to refill when calorie intake increases again.
49
What factors influence where the body stores fat?
Genetics and hormones influence fat storage in specific areas such as abdomen, thighs, and hips.
50
What physiological changes may occur after weight loss that contribute to weight regain?
The body may lower its metabolic rate and increase hunger signals to restore lost fat.
51
Why is surgery often needed for meniscal tears in the knee joint?
Most of the cartilage lacks blood supply, making natural healing unlikely, and torn tissue can impair joint function.
52
True or False: The number of fat cells decreases during weight loss.
False
53
Fill in the blank: The knee joint is susceptible to injury involving the tearing of _______.
[cartilage pads]
54
What can happen if torn tissue in the knee joint is not treated?
It can impair joint function or cause further damage.