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Flashcards in Toxicology and Psychology Deck (70)
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1

Acetaminophen

Pain and fever
Non-narcotic analgesic, not anti-inflammatory
Toxic to liver - antidote is activated charcoal and n-acetylcysteine

2

Acyclovir

Herpes infections
Antiviral

3

Aspirin

Pain and fever
NSAID antidote is IV fluids and sodium bicarb
Overdose - Tinnitus and respiratory acidosis

4

Benadryl

Allergic reaction
Antihistamine - anticholinergic

5

Cocaine

Pain and recreation
Non-opioid narcotic - local anesthetic effect, dilated pupils

6

Codeine

Pain and recreation
Narcotic

7

Chlorpromazine

Schizophrenia
Anti-psychotic

8

Colchicine

Gout
Anti-inflammatory

9

Heroin

Pain and recreation
Opioid narcotic (poisoning looks like pinpoint pupils, coma and respiratory depression)
Antidote nalaxone

10

Ibuprofen

Pain and fever
NSAID

11

Iron sulfate

Anemia
Mineral supplement - OD vomiting, diarrhea, ab pain, liver failure
Antidote desferoxamine

12

Imipramine

Depression, fibromyalgia, CFS
Tricyclic antidepressant - anticholinergic

13

Haldol

Insomnia
Sedative hypnotic

14

Naprosyn

Pain
NSAID

15

Valium

Anxiety and insomnia
Benzodiazipine sedative

16

Response to exposure that is less than expected

Antagonistic

17

Cancer risk values are over how many years?

70

18

Lethal dose 0/50

Lowest dose of a substance (dose of) introduced by any route other than inhalation which has been reported to have caused death in humans or animals (cause death 50% of defined experimental animal population)

19

LOAEL

Lowest observed adverse effect level to cause harm effects in people or animals

20

MRL

Minimal risk level
Dose of substance below which it is unlikely to cause harm

21

NOAEL

Highest tested dose that has been reported to have NO adverse effects level on people/animals

22

Any substance that injures or kills living things

Toxicant

23

VOC

Volatile organic compound - readily evaporate into air
Benzene, toluene, methylene chloride

24

If pt has HTN, elevated temperature, dilated pupils, rapid pulse what is the overdose on?

Antidepressants

25

Aflatotoxin
Poisoning

Poison produced by fungi (Aspergillus flavus)
Liver damage --> hepatocellular carcinoma

26

Arsenic
Poisoning

Chemical interferes w/pyruvate dehydrogenase, smells like garlic antidote is chelating agent like dimercaprol
Headaches, confusion, diarrhea, hematuria, drowsiness

27

Barbituate

Sedative hypnotic drug; respiratory depression, dilated pupils

28

Beta blockers

Tx HTN
Cause hypotension and bradycardia

29

Cholinergic

Mimic ACh
Carbamates, organophosphate (inhibit cholinesterase lead to pinpoint pupils, sweating, vomiting, bradycardia, and wheezing) insecticides (antidote atropine), mushrooms

30

Domoic acid

Neurotoxin produced by harmful algae found in red tide